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PubMed Publications| Keyword search (4,163 papers available) |  |
"Li KZH" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | The effect of hearing ability on dual-task performance following multi-domain training in older adults with mild cognitive impairment: findings from the SYNERGIC trial | Downey RI; Petersen BJ; Mohanathas N; Campos JL; Montero-Odasso M; Bherer L; Pichora-Fuller MK; Bray NW; Burhan AM; Camicioli R; Fraser S; Liu-Ambrose T; Lussier M; Middleton LE; Pieruccini-Faria F; Phillips NA; Li KZH; | 41694460 SOH |
| 2 | Tuned to walk: cue type, beat perception, and gait dynamics during rhythmic stimulation in aging | Parker A; Dalla Bella S; Penhune VB; Young L; Grenet D; Li KZH; | 41661338 PSYCHOLOGY |
| 3 | Auditory Training for Everyday Functioning in Later Life | Li KZH; Campos J; Pichora-Fuller MK; | 41036263 PSYCHOLOGY |
| 4 | Synergistic effects of exercise, cognitive training and vitamin D on gait performance and falls in mild cognitive impairment-secondary outcomes from the SYNERGIC trial | Pieruccini-Faria F; Son S; Zou G; Almeida QJ; Middleton LE; Bray NW; Lussier M; Shoemaker JK; Speechley M; Liu-Ambrose T; Burhan AM; Camicioli R; Li KZH; Fraser S; Berryman N; Bherer L; Montero-Odasso M; | 40966614 SOH |
| 5 | Realistic dual-task listening-while-balancing in older adults with normal hearing and hearing loss with and without hearing aids | Mohanathas N; Montanari L; Gabriel GA; Downey R; Li KZH; Campos JL; | 39567644 PERFORM |
| 6 | Exploring the challenges of avoiding collisions with virtual pedestrians using a dual-task paradigm in individuals with chronic moderate to severe traumatic brain injury | de Aquino Costa Sousa T; Gagnon IJ; Li KZH; McFadyen BJ; Lamontagne A; | 38755606 PERFORM |
| 7 | Effects of Exercise Alone or Combined With Cognitive Training and Vitamin D Supplementation to Improve Cognition in Adults With Mild Cognitive Impairment: A Randomized Clinical Trial | Montero-Odasso M; Zou G; Speechley M; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Bray NW; Li KZH; Fraser S; Pieruccini-Faria F; Berryman N; Lussier M; Shoemaker JK; Son S; Bherer L; | 37471089 PERFORM |
| 8 | The association between information and communication technologies, loneliness and social connectedness: A scoping review | Petersen B; Khalili-Mahani N; Murphy C; Sawchuk K; Phillips N; Li KZH; Hebblethwaite S; | 37034933 PSYCHOLOGY |
| 9 | Multiple routes to help you roam: A comparison of training interventions to improve cognitive-motor dual-tasking in healthy older adults | Downey R; Bherer L; Pothier K; Vrinceanu T; Intzandt B; Berryman N; Lussier M; Vincent T; Karelis AD; Nigam A; Vu TTM; Bosquet L; Li KZH; | 36408116 PERFORM |
| 10 | Sex-Related Differences in the Associations Between Montreal Cognitive Assessment Scores and Pure-Tone Measures of Hearing | Al-Yawer F; Bruce H; Li KZH; Pichora-Fuller MK; Phillips NA; | 35226818 PERFORM |
| 11 | A comparison of the effect of physical activity and cognitive training on dual-task performance in older adults | Vrinceanu T; Blanchette CA; Intzandt B; Lussier M; Pothier K; Vu TTM; Nigam A; Bosquet L; Karelis AD; Li KZH; Berryman N; Bherer L; | 34865009 PERFORM |
| 12 | A comparison of physical exercise and cognitive training interventions to improve determinants of functional mobility in healthy older adults | Pothier K; Vrinceanu T; Intzandt B; Bosquet L; Karelis AD; Lussier M; Vu TTM; Nigam A; Li KZH; Berryman N; Bherer L; | 33774144 PERFORM |
| 13 | Gait variability across neurodegenerative and cognitive disorders: Results from the Canadian Consortium of Neurodegeneration in Aging (CCNA) and the Gait and Brain Study. | Pieruccini-Faria F, Black SE, Masellis M, Smith EE, Almeida QJ, Li KZH, Bherer L, Camicioli R, Montero-Odasso M | 33590967 PSYCHOLOGY |
| 14 | Synergistic effects of cognitive training and physical exercise on dual-task performance in older adults | Bherer L; Gagnon C; Langeard A; Lussier M; Desjardins-Crépeau L; Berryman N; Bosquet L; Vu TTM; Fraser S; Li KZH; Kramer AF; | 32803232 PERFORM |
| 15 | Consensus on Shared Measures of Mobility and Cognition: From the Canadian Consortium on Neurodegeneration in Aging (CCNA). | Montero-Odasso M, Almeida QJ, Bherer L, Burhan AM, Camicioli R, Doyon J, Fraser S, Muir-Hunter S, Li KZH, Liu-Ambrose T, McIlroy W, Middleton L, Morais JA, Sakurai R, Speechley M, Vasudev A, Beauchet O, Hausdorff JM, Rosano C, Studenski S, Verghese J, Canadian Gait and Cognition Network | 30101279 PERFORM |
| 16 | The Effects of Age and Hearing Loss on Dual-Task Balance and Listening. | Bruce H, Aponte D, St-Onge N, Phillips N, Gagné JP, Li KZH | 28486677 PERFORM |
| 17 | A comparison of the impact of physical exercise, cognitive training and combined intervention on spontaneous walking speed in older adults. | Pothier K, Gagnon C, Fraser SA, Lussier M, Desjardins-Crépeau L, Berryman N, Kergoat MJ, Vu TTM, Li KZH, Bosquet L, Bherer L | 29235076 PERFORM |
| 18 | Cognitive Involvement in Balance, Gait and Dual-Tasking in Aging: A Focused Review From a Neuroscience of Aging Perspective | Li KZH; Bherer L; Mirelman A; Maidan I; Hausdorff JM; | 30425679 PERFORM |
| Title: | The effect of hearing ability on dual-task performance following multi-domain training in older adults with mild cognitive impairment: findings from the SYNERGIC trial | ||||
| Authors: | Downey RI, Petersen BJ, Mohanathas N, Campos JL, Montero-Odasso M, Bherer L, Pichora-Fuller MK, Bray NW, Burhan AM, Camicioli R, Fraser S, Liu-Ambrose T, Lussier M, Middleton LE, Pieruccini-Faria F, Phillips NA, Li KZH | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/41694460/ | ||||
| DOI: | 10.3389/fnagi.2025.1716733 | ||||
| Publication: | Frontiers in aging neuroscience | ||||
| Keywords: | cognitive training; dual-task; exercise; gait; hearing loss; mild cognitive impairment; multi-domain training; | ||||
| PMID: | 41694460 | Category: | Date Added: | 2026-02-16 | |
| Dept Affiliation: |
SOH
1 Department of Psychology/Centre for Research in Human Development, Concordia University, Montréal, QC, Canada. 2 School of Health, Concordia University, Montréal, QC, Canada. 3 Department of Psychology, University of Toronto, Toronto, ON, Canada. 4 KITE-Toronto Rehabilitation Institute, University Health Network, Toronto, ON, Canada. 5 Department of Medicine, Division of Geriatric Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada. 6 Gait and Brain Lab, Parkwood Institute, Lawson Health Research Institute, London, ON, Canada. 7 Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada. 8 Département de Médecine, Université de Montréal, Montréal, QC, Canada. 9 Centre de Recherche de l'Institut de Cardiologie de Montréal, Montréal, QC, Canada. 10 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, QC, Canada. 11 Recovery and Performance Lab, Division of Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada. 12 Ontario Shores Centre for Mental Health Sciences, Whitby, ON, Canada. 13 Division of Geriatric Psychiatry, Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. 14 Department of Medicine (Neurology), University of Alberta, Edmonton, AB, Canada. 15 Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB, Canada. 16 Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada. 17 The Centre for Aging SMART, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada. 18 Djavad Mowafaghian Centre for Brain Health, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada. 19 Department of Kinesiology and Health Sciences, University of Waterloo, ON, Canada. 20 Schlegel-UW Research Institute for Aging, Waterloo, ON, Canada. |
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Description: |
Background: Hearing loss is one of the largest potentially modifiable risk factors for dementia and is linked with poor cognitive-motor dual-task performance (e.g., walking while performing a cognitive task). Hearing loss is more prevalent and severe in males, whereas dementia is more prevalent in females. Physical exercise and cognitive interventions appear promising in improving dual-tasking in older adults; however, it is currently unclear whether hearing ability affects training efficacy on dual-task outcomes in older adults with mild cognitive impairment (MCI), and whether sex influences this effect. Objective: The primary aim of this study was to examine whether hearing ability affects dual-task performance at baseline and after training in individuals with MCI, and whether sex further influences these relationships, irrespective of intervention arm. Methods: Secondary data was analysed from 75 participants with MCI (Mage = 73.66 ± 6.67) enrolled in the SYNERGIC trial. Hearing ability was assessed using self-report and behavioral measures. Participants completed a 20-week intervention: (1) Exercise (aerobic-resistance exercise + sham cognitive training; n = 31), (2) Multi-Domain Training (aerobic-resistance exercise + cognitive training; n = 32), or (3) Placebo Training (balance and toning exercises + sham cognitive training; n = 12). Primary outcomes included dual-task gait and cognitive performance. Results: At baseline, poorer hearing predicted worse dual-task performance, particularly in males. Dual-task gait variability significantly improved following Multi-Domain Training in participants with a greater degree of self-reported hearing complaints. Sex-stratified analyses revealed that females with more hearing complaints improved more across all interventions, while in the Multi-Domain group, males with poorer objective hearing and females with better hearing showed the greatest gains. Additionally, in those with poorer hearing, lower cognitive scores (MoCA) predicted greater improvements after Multi-Domain Training, but a decline after Placebo Training. Conclusion: Hearing ability, sex, and cognitive status appear to interact to influence the effects of exercise and cognitive training on dual-task performance in older adults with MCI. Multi-Domain Training appears particularly beneficial for those with hearing loss (who are male and/or have lower cognitive status), highlighting the need for personalized interventions to preserve function and slow decline in this at-risk population. Clinical trial registration: https://www.clinicaltrials.gov/ct2/show/NCT02808676, NCT02808676. |
