Keyword search (4,163 papers available)

"Collins DL" Authored Publications:

Title Authors PubMed ID
1 The PREVENT-AD cohort: Accelerating Alzheimer s disease research and treatment in Canada and beyond Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Fajardo Valdez A; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Strikwerda-Brown C; Tardif CL; Gauthier CJ; Descoteaux M; Dadar M; Vachon-Presseau É; Baril AA; Ducharme S; Montembeault M; Geddes MR; Soucy JP; Rajah N; Laforce R; Bocti C; Davatzikos C; Bellec L; Rosa-Neto P; Baillet S; Evans AC; Collins DL; Chakravarty MM; Blennow K; Zetterbe 41020412
SOH
2 The PREVENT-AD cohort: accelerating Alzheimer s disease research and treatment in Canada and beyond Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Valdez AF; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Strikwerda-Brown C; Tardif CL; Gauthier CJ; Descoteaux M; Dadar M; Vachon-Presseau É; Baril AA; Ducharme S; Montembeault M; Geddes MR; Soucy JP; Rajah N; Laforce R; Bocti C; Davatzikos C; Bellec L; Rosa-Neto P; Baillet S; Evans AC; Collins DL; Chakravarty MM; Blennow K; Zetterberg H; S 40778177
PSYCHOLOGY
3 Assessment of cognitive load in the context of neurosurgery Di Giovanni DA; Kersten-Oertel M; Drouin S; Collins DL; 40650801
PERFORM
4 A database of magnetic resonance imaging-transcranial ultrasound co-registration Alizadeh M; Collins DL; Kersten-Oertel M; Xiao Y; 39920905
SOH
5 Use of lecanemab and donanemab in the Canadian healthcare system: Evidence, challenges, and areas for future research Smith EE; Phillips NA; Feldman HH; Borrie M; Ganesh A; Henri-Bhargava A; Desmarais P; Frank A; Badhwar A; Barlow L; Bartha R; Best S; Bethell J; Bhangu J; Black SE; Bocti C; Bronskill SE; Burhan AM; Calon F; Camicioli R; Campbell B; Collins DL; Dadar M; DeMarco ML; Ducharme S; Duchesne S; Einstein G; Fisk JD; Gawryluk JR; Grossman L; Ismail Z; Itzhak I; Joshi M; Harrison A; Kroger E; Kumar S; Laforce R; Lanctot KL; Lau M; Lee L; Masellis M; Massoud F; Mitchell SB; Montero-Odasso M; Myers Barnett K; Nygaard HB; Pasternak SH; Peters J; Rajah MN; Robillard JM; Rockwood K; Rosa-Neto P; Seitz DP; Soucy JP; Trenaman SC; Wellington CL; Zadem A; Chertkow H; 39893139
CONCORDIA
6 Design, manufacturing, and multi-modal imaging of stereolithography 3D printed flexible intracranial aneurysm phantoms Yalman A; Jafari A; Léger É; Mastroianni MA; Teimouri K; Savoji H; Collins DL; Kadem L; Xiao Y; 39546636
BIOLOGY
7 A dataset of multi-contrast unbiased average MRI templates of a Parkinson's disease population Madge V; Fonov VS; Xiao Y; Zou L; Jackson C; Postuma RB; Dagher A; Fon EA; Collins DL; 37213552
IMAGING
8 The BigBrainWarp toolbox for integration of BigBrain 3D histology with multimodal neuroimaging Paquola C; Royer J; Lewis LB; Lepage C; Glatard T; Wagstyl K; DeKraker J; Toussaint PJ; Valk SL; Collins DL; Khan A; Amunts K; Evans AC; Dickscheid T; Bernhardt BC; 34431476
IMAGING
9 MARIN: an open-source mobile augmented reality interactive neuronavigation system. Léger É; Reyes J; Drouin S; Popa T; Hall JA; Collins DL; Kersten-Oertel M; 32323206
PERFORM
10 Cyberinfrastructure for Open Science at the Montreal Neurological Institute. Das S, Glatard T, Rogers C, Saigle J, Paiva S, MacIntyre L, Safi-Harab M, Rousseau ME, Stirling J, Khalili-Mahani N, MacFarlane D, Kostopoulos P, Rioux P, Madjar C, Lecours-Boucher X, Vanamala S, Adalat R, Mohaddes Z, Fonov VS, Milot S, Leppert I, Degroot C, Durcan TM, Campbell T, Moreau J, Dagher A, Collins DL, Karamchandani J, Bar-Or A, Fon EA, Hoge R, Baillet S, Rouleau G, Evans AC 28111547
IMAGING
11 Dehydroepiandrosterone impacts working memory by shaping cortico-hippocampal structural covariance during development. Nguyen TV, Wu M, Lew J, Albaugh MD, Botteron KN, Hudziak JJ, Fonov VS, Collins DL, Campbell BC, Booij L, Herba C, Monnier P, Ducharme S, McCracken JT 28946055
PSYCHOLOGY
12 Cognitive load associations when utilizing auditory display within image-guided neurosurgery. Plazak J, DiGiovanni DA, Collins DL, Kersten-Oertel M 30997635
ENCS
13 Quantifying attention shifts in augmented reality image-guided neurosurgery. Léger É, Drouin S, Collins DL, Popa T, Kersten-Oertel M 29184663
PERFORM
14 Structural Brain Alterations Associated with Rapid Eye Movement Sleep Behavior Disorder in Parkinson's Disease. Boucetta S, Salimi A, Dadar M, Jones BE, Collins DL, Dang-Vu TT 27245317
PERFORM
15 Deformable registration of preoperative MR, pre-resection ultrasound, and post-resection ultrasound images of neurosurgery. Rivaz H, Collins DL 25373447
PERFORM
16 A dataset of multi-contrast population-averaged brain MRI atlases of a Parkinson׳s disease cohort. Xiao Y, Fonov V, Chakravarty MM, Beriault S, Al Subaie F, Sadikot A, Pike GB, Bertrand G, Collins DL 28491942
PERFORM
17 Combining intraoperative ultrasound brain shift correction and augmented reality visualizations: a pilot study of eight cases. Gerard IJ, Kersten-Oertel M, Drouin S, Hall JA, Petrecca K, De Nigris D, Di Giovanni DA, Arbel T, Collins DL 29392162
PERFORM
18 Gesture-based registration correction using a mobile augmented reality image-guided neurosurgery system. Léger É, Reyes J, Drouin S, Collins DL, Popa T, Kersten-Oertel M 30800320
PERFORM

 

Title:The PREVENT-AD cohort: Accelerating Alzheimer s disease research and treatment in Canada and beyond
Authors:Villeneuve SPoirier JBreitner JCSTremblay-Mercier JRemz JRaoult JMYakoub YGallego-Rudolf JQiu TFajardo Valdez AMohammediyan BJavanray MMetz ASanami SOurry VWearn APastor-Bernier AEdde MGonneaud JStrikwerda-Brown CTardif CLGauthier CJDescoteaux MDadar MVachon-Presseau ÉBaril AADucharme SMontembeault MGeddes MRSoucy JPRajah NLaforce RBocti CDavatzikos CBellec LRosa-Neto PBaillet SEvans ACCollins DLChakravarty MMBlennow KZetterbe
Link:https://pubmed.ncbi.nlm.nih.gov/41020412/
DOI:10.1002/alz.70653
Publication:Alzheimer s & dementia : the journal of the Alzheimer s Association
Keywords:biomarkersclinical progressioncognitiondata repositoryneuroimagingpreclinical
PMID:41020412 Category: Date Added:2025-09-29
Dept Affiliation: SOH
1 StoP-AD Centre, Douglas Mental Health University Institute, McGill University, Montréal, Quebec, Canada.
2 Department of Psychiatry, McGill University, Montréal, Quebec, Canada.
3 McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Montréal, Quebec, Canada.
4 Cerebral Imaging Centre, Douglas Mental Health University Institute, McGill University, Montréal, Quebec, Canada.
5 Integrated Program in Neuroscience, McGill University, Montréal, Quebec, Canada.
6 Research Center of the CIUSSS-NIM, Hôpital du Sacré-Coeur de Montréal, Montreal, Quebec, Canada.
7 Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, Quebec, Canada.
8 Department of Physics, Concordia University, Montréal, Quebec, Canada.
9 Department of Neurology and Neurosurgery, McGill University, Montréal, Quebec, Canada.
10 Faculté des sciences, Département d'informatique, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
11 Normandie Univ, UNICAEN, INSERM, U1237, PhIND "Physiopathology and Imaging of Neurological Disorders", NeuroPresage Team, GIP Cyceron, Caen, France.
12 School of Psychological Science, The University of Western Australia, Perth, Western Australia, Australia.
13 Department Biomedical Engineering, McGill University, Montréal, Quebec, Canada.
14 Centre ÉPIC, Montreal Heart Institute, Montréal, Quebec, Canada.
15 School of Health, Concordia University, Montréal, Quebec, Canada.
16 Faculty of Dental Medicine and Oral Health Sciences, McGill University, Montreal, Quebec, Canada.
17 Department of Anesthesia, Faculty of Medicine and Health Sciences, McGill University, Montreal, Quebec, Canada.
18 Alan Edwards Center for Research on Pain, McGill University, Montreal, Quebec, Canada.
19 Department of Psychology, Toronto Metropolitan University, Toronto, Ontario, Canada.
20 Clinique interdisciplinaire de mémoire, CHU de Québec affilié à l'Université Laval, Québec, Quebec, Canada.
21 Division of Neurology, Department of Medicine, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
22 AI2D Center for AI and Data Science for Integrated Diagnostics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
23 Psychology Department, Université de Montréal, Montréal, Quebec, Canada.
24 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, Quebec, Canada.
25 Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
26 Clinical Neurochemistry Lab, Sahlgrenska University Hospital, Mölndal, Sweden.
27 Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France.
28 Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, Anhui, P.R. China.
29 Department of Neurodegenerative Disease, University College London Institute of Neurology, London, UK.
30 UK Dementia Research Institute at UCL, London, UK.
31 Hong Kong Center for Neurodegenerative Diseases, InnoHK, Hong Kong, China.
32 Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
33 Department of Physiology and Pharmacology, Université de Montréal, Montréal, Quebec, Canada.
34 Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.

Description:

The PResymptomatic EValuation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) is an investigator-driven study that was created in 2011 and enrolled cognitively normal older adults with a family history of sporadic AD. Participants are deeply phenotyped and have now been followed annually for more than 12 years (median follow-up 8.0 years, SD 3.1). Multimodal magnetic resonance imaging (MRI), genetic, neurosensory, clinical, cerebrospinal fluid, and cognitive data collected until 2017 on 348 participants who agreed to open sharing with the neuroscience community were already available. We now share a new release including 6 years of additional follow-up cognitive data, and additional MRI follow-ups, clinical progression, new longitudinal behavioral and lifestyle measures (questionnaires, actigraphy), longitudinal AD plasma biomarkers, amyloid-beta and tau positron emission tomography (PET), magnetoencephalography, as well as neuroimaging analytic measures from all MRI modalities. We describe the PREVENT-AD study, the data shared with the global research community, as well as the model we created to sustain longitudinal follow-ups while also allowing new innovative data collection. HIGHLIGHTS: The PResymptomatic EValuation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) is a single-site longitudinal study that started in 2011 with annual follow-up data collection on individuals at risk of Alzheimer's disease who were all cognitively normal at enrolment. All 387 participants were enrolled between 2011 and 2017 and 306 (79%) of these participants were still in the study as of December 2023. While the PREVENT-AD dataset was not originally planned to be shared with the global research community, 348 participants retrospectively consented for their data to be shared with researchers worldwide. The first release of data was in 2019. We now share a second release that includes 6 years of additional follow-up visits, information on clinical progression and novel cognitive, behavioral, genetic, plasma and neuroimaging (amyloid and tau positron emission tomography [PET], magnetoencephalography [MEG], and new magnetic resonance imaging [MRI] sequences) data. It also includes analytic outputs for neuroimaging modalities.





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