1 Department of Psychiatry, University of Pittsburgh, Suite 223, 450 Technology Drive, Pittsburgh, PA, 15224, USA; School of Biomedical Sciences and Pharmacy, University of Newcastle, MS306, University Drive, Callaghan, NSW, 2308, Australia. Electronic address: lizzie.manning@newcastle.edu.au.
2 Centre for Neuroscience and Regenerative Medicine, University of Technology Sydney (St. Vincent's Campus), 405 Liverpool St, Darlinghurst, NSW, 2010, Australia; St. Vincent's Centre for Applied Medical Research, St. Vincent's Hospital Sydney Limited, 405 Liverpool St, Darlinghurst, NSW, 2010, Australia. Electronic address: Laura.Bradfield@uts.edu.au.
3 Department of Psychology/Centre for Studies in Behavioural Neurobiology, Concordia University, Montreal, Canada. Electronic address: mihaela.iordanova@concordia.ca.

Adaptive behaviour under conflict: deconstructing extinction, reversal, and active avoidance learning.

Neurosci Biobehav Rev. 2020 Oct 06; :

Authors: Manning EE, Bradfield LA, Iordanova MD

Abstract

In complex environments, organisms must respond adaptively to situations despite conflicting information. Under natural (i.e. non-laboratory) circumstances, it is rare that cues or responses are consistently paired with a single outcome. Inconsistent pairings are more common, as are situations where cues and responses are associated with multiple outcomes. Such inconsistency creates conflict, and a response that is adaptive in one scenario may not be adaptive in another. Learning to adjust responses accordingly is important for species to survive and prosper. Here we review the behavioural and brain mechanisms of responding under conflict by focusing on three popular behavioural procedures: extinction, reversal learning, and active avoidance. Extinction involves adapting from reinforcement to non-reinforcement, reversal learning involves swapping the reinforcement of cues or responses, and active avoidance involves performing a response to avoid an aversive outcome, which may conflict with other defensive strategies. We note that each of these phenomena relies on somewhat overlapping neural circuits, suggesting that such circuits may be critical for the general ability to respond appropriately under conflict.

PMID: 33035525 [PubMed - as supplied by publisher]