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A Systematic Review and Meta-Analysis of Actigraphy-Assessed Sleep Effects of Exercise in Adults

Author(s): Emmanuel Frimpong, Melodee Mograss, Manlu Xu, Huu Thien Tran, Zoey Ferron, Nicole Milbrath, Tatiana Ifrah, Thien Thanh Dang-Vu

Adequate physical exercise leads to a good quality of sleep. Concernigly, over a third of adults aged 18-64 years do not meet the recommended sleep duration (i.e., 7-9 hours/night), while about a third of adults fail to meet the physical activity guidelines of achieving at least 150 minutes of mo ...

Article GUID: CRD420251104708


Open-source platforms to investigate analytical flexibility in neuroimaging

Author(s): Sanz-Robinson J; Wang M; McPherson B; Chatelain Y; Kennedy D; Glatard T; Poline JB;

Researchers in brain imaging have access to a multitude of analysis tools, many of which carry out the same or similar tasks but yield different results when applied to the same data. This analytical flexibility often undermines reproducibility and raises concerns about the robustness of neuroimaging studies. However, the array of software packages to inv ...

Article GUID: 40800896


Feasibility analysis of recycling and repurposing end-of-life vehicle batteries in isolated island areas: A case study in British Columbia, Canada

Author(s): Wang Z; Lyu L; Huang G; An C;

The increasing adoption of electric vehicles (EVs) is widely recognized as a pivotal strategy for mitigating climate change. However, the surge in EV usage brings significant challenges regarding the end-of-life management of lithium-ion batteries, particularly in geographically isolated islands, such as Vancouver Island, Canada. This study addresses the ...

Article GUID: 40795495


An analytical framework to decode socioeconomic interplays in pesticides and fertilizer container collection patterns using land dynamics metrics

Author(s): Chowdhury R; Karimi N; Xu X; An C; Gitifar A; Ng KTW;

This study analyzes pesticide and fertilizer container collection trends across Canadian agricultural regions over a seven-year period from 2016 to 2022 through an analytical framework and proposed two land metrics. A 28.3 % decrease in the collection of small empty pesticide and fertilizer containers (EPFCs) coincides with a 41.4 % increase in the collec ...

Article GUID: 40795518


Miniaturized scalable arrayed CRISPR screening in primary cells enables discovery at the single donor resolution

Author(s): Patel MA; Boribong BP; Sinha H; Xiao B; Xie K; Vo PQN; Chin AB; Ellouzi A; Little SR; Shih S; Wu H; Muller WJ; Hirukawa A;

High-efficiency gene editing in primary human cells is critical for advancing therapeutic development and functional genomics, yet conventional electroporation platforms often require high cell input and are poorly suited to parallelized experiments. Here we introduce a next-generation digital mi ...

Article GUID: 40790054


Artificial intelligence-assisted identification of condensing osteitis and idiopathic osteosclerosis on panoramic radiographs

Author(s): Yuksel IB; Boudesh A; Ghanbarzadehchaleshtori M; Ozsoy SC; Bahrilli S; Mohammadi R; Altindag A;

Idiopathic osteosclerosis (IOS) and condensing osteitis (CO) represent radiopaque lesions often detected incidentally within the jaws, posing substantial diagnostic challenges due to their overlapping radiographic characteristics. The objective of this study was to assess the diagnostic efficacy ...

Article GUID: 40790082


MedCLIP-SAMv2: Towards universal text-driven medical image segmentation

Author(s): Koleilat T; Asgariandehkordi H; Rivaz H; Xiao Y;

Segmentation of anatomical structures and pathologies in medical images is essential for modern disease diagnosis, clinical research, and treatment planning. While significant advancements have been made in deep learning-based segmentation techniques, many of these methods still suffer from limitations in data efficiency, generalizability, and interactivi ...

Article GUID: 40779830


A portrait of online gambling: a look at a transformation amid a pandemic

Author(s): Kairouz S; Savard AC; Murch WS; Dixon MR; Martin NB; Brodeur M; Dauphinais S; Ferland F; Hamel D; Dufour M; French M; Monson E; Van Mourik V; Morvannou A;

Background: The COVID-19 pandemic brought about an extraordinary societal context in which the gambling offer was modified to meet public health measures intended to curb viral transmission. With many land-based gambling venues being forced to close, gambling opportunities were left almost exclus ...

Article GUID: 40770758


Polyphenolic Gallotannins 1,3,6-Tri-O-galloyl-β-d-glucose and Corilagin Attenuate IAPP Amyloid Formation and Cytotoxicity by Primarily Targeting Secondary Nucleation

Author(s): Khalifa J; Sulaimon R; Côté-Cyr M; Nguyen PT; Peslherbe G; Bourgault S; Gaudreault R;

Protein misfolding and subsequent aggregation into insoluble amyloid deposits are associated with various diseases, including Alzheimer's disease, systemic amyloidosis, and type 2 diabetes mellitus (T2DM). In T2DM, the peptide hormone islet amyloid polypeptide (IAPP), which regulates glucose homeostasis, aggregates in the pancreas, forming soluble cyt ...

Article GUID: 40768411


Land-use history causes differences in park nighttime cooling capacity and forest structure

Author(s): Richmond IC; Paulauskas MA; Padvaiskas E; Gonzàlez Sinisterra LC; Hutt-Taylor K; Robitaille AL; Ziter CD;

Cities are temporally dynamic ecosystems that experience continuous redevelopment over time. Urban parks, which provide critical benefits to resident wellbeing, are developed on different land-use types and contain natural elements that are susceptible to the effects of historical decision-making ...

Article GUID: 40761092


Prevalent vertebral fracture is associated with incident cardiovascular disease events in older individuals referred for bone densitometry

Author(s): Schousboe JT; Monchka BA; Davidson JM; Kimelman D; Gilani SZ; Ilyas Z; Reid S; Lewis JR; Leslie WD;

Background: It is unknown if prevalent vertebral fracture (PVFx) captured on bone density vertebral fracture assessment (VFA) images predicts incident CVD events. Methods: 11,760 individuals (mean [SD] age 75.7 [6.8] years, 94 % female) had VFA contemporaneously with bone densitometry in Manitob ...

Article GUID: 40759230


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