Author(s): Leake J; Leidl DM; Lay BPP; Fam JP; Giles MC; Qureshi OA; Westbrook RF; Holmes NM;
Activity in the basolateral amygdala complex (BLA) is needed to encode fears acquired through contact with both innate sources of danger (i.e., things that are painful) and learned sources of danger (e.g., being threatened with a gun). However, within the B ...
Article GUID: 37963767
Author(s): Tuval Keidar
It is widely accepted that Pavlovian fear conditioning requires activation of NMDA receptors (NMDARs) in the basolateral amygdala complex (BLA). However, it was recently shown that activation of NMDAR in the BLA is only required for fear conditioning when d ...
Article GUID: 37607821
Author(s): Omar A Qureshi
This study examined the effect of danger on consolidation of neutral information in two regions of the rat (male and female) medial temporal lobe: the perirhinal cortex (PRh) and basolateral amygdala complex (BLA). The neutral information was the associatio ...
Article GUID: 36927572
Author(s): Lay BPP; Koya E; Hope BT; Esber GR; Iordanova MD;
Background: Adaptive behavior depends on the delicate and dynamic balance between acquisition and extinction memories. Disruption of this balance, particularly when the extinction of memory loses control over behavior, is the root of treatment failure of ma ...
Article GUID: 36336498
Author(s): Williams-Spooner MJ; Delaney AJ; Westbrook RF; Holmes NM;
It is widely accepted that activation of N-methyl-D-aspartate receptors (NMDAR) is necessary for the formation of fear memories in the basolateral amygdala complex (BLA). This acceptance is based on findings that blockade of NMDAR in the BLA disrupts Pavlov ...
Article GUID: 35410880
Author(s): Fernandes MF; Lau D; Sharma S; Fulton S;
The central signaling actions of cytokines are mediated by signal transducer and activator of transcription (STAT3). STAT3 activation plays a pivotal role in the behavioral responses to the adiposity hormone leptin, including in midbrain dopamine (DA) neuro ...
Article GUID: 33872705
Author(s): Iordanova MD, Yau JO, McDannald MA, Corbit LH
Prediction error, defined by the discrepancy between real and expected outcomes, lies at the core of associative learning. Behavioural investigations have provided evidence that prediction error up- and down-regulates associative relationships, and allocate ...
Article GUID: 33453307
Author(s): Manning EE, Bradfield LA, Iordanova MD
In complex environments, organisms must respond adaptively to situations despite conflicting information. Under natural (i.e. non-laboratory) circumstances, it is rare that cues or responses are consistently paired with a single outcome. Inconsistent pairin ...
Article GUID: 33035525
Author(s): Lafferty CK, Yang AK, Mendoza JA, Britt JP
Cell Rep. 2020 Mar 17;30(11):3729-3742.e3 Authors: Lafferty CK, Yang AK, Mendoza JA, Britt JP
Article GUID: 32187545
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