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PubMed Publications| Keyword search (4,163 papers available) |  |
Newest Concordia Publications (of 75):
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Nicotine Suppresses Human Memory Th Cell Subsets With Preferential Effects on Central Memory Th Cells in an α7 Nicotinic Acetylcholine Receptor-Dependent Manner | Gholizadeh F; Hajiaghayi M; Rahbari N; Choi JS; Heidt S; Como A; Kazerouni M; Kargar M; Pinard-LaRoche A; Shih SCC; Darlington PJ; | 41928597 SOH |
| 2 | Nebivolol prevents exhausted T cells and enhances cytotoxicity against MCF-7 breast cancer cells in a β2-adrenergic receptor-dependent manner | Hajiaghayi M; Gholizadeh F; Rahbari N; Emamnia N; Shih SCC; Darlington PJ; | 41906691 SOH |
| 3 | Strengthening and Targeted Rehabilitation for Optimal Neuromuscular Gains for chronic BACK pain (STRONG-BACK): protocol for a randomised controlled trial in participants with primary nociceptive pain drivers | Fortin M; Rosenstein B; Bertrand C; Vaillancourt N; Wright A; Montpetit C; Macedo L; Elliott J; Cook CE; Tousignant-Laflamme Y; Ma J; Pagé MG; Dover G; Dang-Vu TT; Weber MH; | 41876162 SOH |
| 4 | A Fully Virtual Graded Exertion Test Is Safe and Feasible in Symptomatic and Asymptomatic Children With Concussion | Coupal J; Shabanova D; Gagnon I; Grilli L; Beaulieu C; Teel E; | 41816309 SOH |
| 5 | Achilles tendon ultrasound-derived properties of the dominant and non-dominant jumping leg of university basketball athletes: relation with performance, range of motion, and injury | Soontjens O; Busner J; Fortin M; | 41783785 SOH |
| 6 | Exploring correlates of weight bias among university students in diverse programs | Jeanningros A; Côté M; Forouhar V; Aimé A; Lavallière M; Blackburn P; Maïano C; Alberga AS; Baillot A; | 41718586 SOH |
| 7 | Beyond the wound: A scoping review of the psychosocial impact of diabetes-related foot ulcers | Hanlon M; McGuire BE; MacGilchrist C; Kirwan E; Neachtain DN; Dhatariya K; Blanchette V; Durand H; Dragomir A; McIntosh C; | 41721498 SOH |
| 8 | The effect of postoperative rehabilitation on outcomes in patients with degenerative cervical myelopathy (DCM): A systematic review | Montpetit C; Kobaisi A; Lantz JM; Chauhan RV; Anderson DB; Fortin M; | 41693706 SOH |
| 9 | The effect of hearing ability on dual-task performance following multi-domain training in older adults with mild cognitive impairment: findings from the SYNERGIC trial | Downey RI; Petersen BJ; Mohanathas N; Campos JL; Montero-Odasso M; Bherer L; Pichora-Fuller MK; Bray NW; Burhan AM; Camicioli R; Fraser S; Liu-Ambrose T; Lussier M; Middleton LE; Pieruccini-Faria F; Phillips NA; Li KZH; | 41694460 SOH |
| 10 | How vigilance states influence source imaging of physiological brain oscillations: evidence from intracranial EEG | Wei X; Afnan J; Avigdor T; von Ellenrieder N; Delaire É; Royer J; Ho A; Minato E; Schiller K; Jaber K; Wang YL; Moye M; Bernhardt BC; Lina JM; Grova C; Frauscher B; | 41687693 SOH |
| 11 | The effectiveness of Cognitive behavioral therapy for insomnia on sleep EEG hyperarousal: a multicentric polysomnographic study | Sforza M; Morin CM; Dang-Vu TT; Pomares FB; Perrault AA; Gouin JP; Bušková J; Janku K; Vgontzas A; Fernandez-Mendoza J; Bastien CH; Riemann D; Baglioni C; Carollo G; Casoni F; Zucconi M; Castronovo V; Galbiati A; Ferini-Strambi L; | 41688421 SOH |
| 12 | Cardiorespiratory fitness in relation to cerebral vascular and metabolic health in older adults with coronary artery disease | Sanami S; Tremblay SA; Potvin-Jutras Z; Rezaei A; Sabra D; Gagnon C; Intzandt B; Mainville-Berthiaume A; Wright L; Gayda M; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ; | 41680492 SOH |
| 13 | Greater cardiorespiratory fitness is associated with higher cerebral blood flow and lower oxygen extraction fraction in healthy older adults | Sanami S; Rezaei A; Tremblay SA; Potvin-Jutras Z; Sabra D; Intzandt B; Gagnon C; Mainville-Berthiaume A; Wright L; Gayda M; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ; | 41543005 SOH |
| 14 | Aquatic therapy compared to standard care for chronic low back pain: a randomized controlled trial | Vaillancourt N; Montpetit C; Rosenstein B; Fortin M; | 41527881 SOH |
| 15 | The ELEVATE-LBP consortium: exercise &, evidence to lead effective vital action in translating excellence for low back pain prevention | Sheeran L; McIlroy S; Wong AYL; Anderson DB; Samartzis D; Bogaert L; Domokos B; Spang C; Fortin M; Hodges PW; Bizzini M; Dvorák J; | 41507623 SOH |
| Title: | The effect of hearing ability on dual-task performance following multi-domain training in older adults with mild cognitive impairment: findings from the SYNERGIC trial | ||||
| Authors: | Downey RI, Petersen BJ, Mohanathas N, Campos JL, Montero-Odasso M, Bherer L, Pichora-Fuller MK, Bray NW, Burhan AM, Camicioli R, Fraser S, Liu-Ambrose T, Lussier M, Middleton LE, Pieruccini-Faria F, Phillips NA, Li KZH | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/41694460/ | ||||
| DOI: | 10.3389/fnagi.2025.1716733 | ||||
| Publication: | Frontiers in aging neuroscience | ||||
| Keywords: | cognitive training; dual-task; exercise; gait; hearing loss; mild cognitive impairment; multi-domain training; | ||||
| PMID: | 41694460 | Category: | Date Added: | 2026-02-16 | |
| Dept Affiliation: |
SOH
1 Department of Psychology/Centre for Research in Human Development, Concordia University, Montréal, QC, Canada. 2 School of Health, Concordia University, Montréal, QC, Canada. 3 Department of Psychology, University of Toronto, Toronto, ON, Canada. 4 KITE-Toronto Rehabilitation Institute, University Health Network, Toronto, ON, Canada. 5 Department of Medicine, Division of Geriatric Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada. 6 Gait and Brain Lab, Parkwood Institute, Lawson Health Research Institute, London, ON, Canada. 7 Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada. 8 Département de Médecine, Université de Montréal, Montréal, QC, Canada. 9 Centre de Recherche de l'Institut de Cardiologie de Montréal, Montréal, QC, Canada. 10 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, QC, Canada. 11 Recovery and Performance Lab, Division of Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada. 12 Ontario Shores Centre for Mental Health Sciences, Whitby, ON, Canada. 13 Division of Geriatric Psychiatry, Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. 14 Department of Medicine (Neurology), University of Alberta, Edmonton, AB, Canada. 15 Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB, Canada. 16 Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada. 17 The Centre for Aging SMART, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada. 18 Djavad Mowafaghian Centre for Brain Health, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada. 19 Department of Kinesiology and Health Sciences, University of Waterloo, ON, Canada. 20 Schlegel-UW Research Institute for Aging, Waterloo, ON, Canada. |
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Description: |
Background: Hearing loss is one of the largest potentially modifiable risk factors for dementia and is linked with poor cognitive-motor dual-task performance (e.g., walking while performing a cognitive task). Hearing loss is more prevalent and severe in males, whereas dementia is more prevalent in females. Physical exercise and cognitive interventions appear promising in improving dual-tasking in older adults; however, it is currently unclear whether hearing ability affects training efficacy on dual-task outcomes in older adults with mild cognitive impairment (MCI), and whether sex influences this effect. Objective: The primary aim of this study was to examine whether hearing ability affects dual-task performance at baseline and after training in individuals with MCI, and whether sex further influences these relationships, irrespective of intervention arm. Methods: Secondary data was analysed from 75 participants with MCI (Mage = 73.66 ± 6.67) enrolled in the SYNERGIC trial. Hearing ability was assessed using self-report and behavioral measures. Participants completed a 20-week intervention: (1) Exercise (aerobic-resistance exercise + sham cognitive training; n = 31), (2) Multi-Domain Training (aerobic-resistance exercise + cognitive training; n = 32), or (3) Placebo Training (balance and toning exercises + sham cognitive training; n = 12). Primary outcomes included dual-task gait and cognitive performance. Results: At baseline, poorer hearing predicted worse dual-task performance, particularly in males. Dual-task gait variability significantly improved following Multi-Domain Training in participants with a greater degree of self-reported hearing complaints. Sex-stratified analyses revealed that females with more hearing complaints improved more across all interventions, while in the Multi-Domain group, males with poorer objective hearing and females with better hearing showed the greatest gains. Additionally, in those with poorer hearing, lower cognitive scores (MoCA) predicted greater improvements after Multi-Domain Training, but a decline after Placebo Training. Conclusion: Hearing ability, sex, and cognitive status appear to interact to influence the effects of exercise and cognitive training on dual-task performance in older adults with MCI. Multi-Domain Training appears particularly beneficial for those with hearing loss (who are male and/or have lower cognitive status), highlighting the need for personalized interventions to preserve function and slow decline in this at-risk population. Clinical trial registration: https://www.clinicaltrials.gov/ct2/show/NCT02808676, NCT02808676. |
