PERFORM Publications

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Title		Authors	PubMed ID
1	From tissue to sound: A new paradigm for medical sonic interaction design	Matinfar S; Dehghani S; Salehi M; Sommersperger M; Navab N; Faridpooya K; Fairhurst M; Navab N;	40222195 CONCORDIA
2	Hyperbranched Polyethylene Ionomers Containing Quaternary Ammonium Ions and Their Functionalization of Nanomaterials	Ye Z; Rahmatinejad J; Raisi B; Dai P;	40214570 ENCS
3	Searching and reporting in Campbell Collaboration systematic reviews: A systematic assessment of current methods	Young S; MacDonald H; Louden D; Ellis UM; Premji Z; Rogers M; Bethel A; Pickup D;	39176233 CONCORDIA
4	Pitavastatin Calcium Confers Fungicidal Properties to Fluconazole by Inhibiting Ubiquinone Biosynthesis and Generating Reactive Oxygen Species	Li W; Feng Y; Feng Z; Wang L; Whiteway M; Lu H; Jiang Y;	38929106 BIOLOGY
5	Advancements in Hybrid Cellulose-Based Films: Innovations and Applications in 2D Nano-Delivery Systems	Ramezani G; Stiharu I; van de Ven TGM; Nerguizian V;	38667550 ENCS
6	What is Learned Determines How Pavlovian Conditioned Fear is Consolidated in the Brain	Leake J; Leidl DM; Lay BPP; Fam JP; Giles MC; Qureshi OA; Westbrook RF; Holmes NM;	37963767 CSBN
7	Engineering the Surface Chemistry and Morphology of Polymeric Carbon Nitrides Towards Greener Heterogeneous Catalysts for Biodiesel Synthesis	de Medeiros TV; Macina A; Bicalho HA; Naccache R;	37058095 CHEMBIOCHEM
8	Oligonucleotides Containing C5-Propynyl Modified Arabinonucleic Acids: Synthesis, Biophysical and Antisense Properties	Pontarelli A; Wilds CJ;	36857293 CHEMBIOCHEM
9	A "biphasic glycosyltransferase high-throughput screen" identifies novel anthraquinone glycosides in the diversification of phenolic natural products	Mohideen FI; Kwan DH;	36682498 CHEMBIOCHEM
10	Photoactivation and conformational gating for manganese binding and oxidation in bacterial reaction centers	Samaei A; Deshmukh SS; Protheroe C; Nyéki S; Tremblay-Ethier RA; Kálmán L;	36216075 PHYSICS
11	Simple, Economical Methods for the Culture of Green Algae for Energy Harvesting from Photosynthesis in a Microfluidic Environment	Kuruvinashetti K; Rahimi S; Pakkiriswami S; Packirisamy M;	34898042 ENCS
12	Binary Cu2-xS Templates Direct the Formation of Quaternary Cu2ZnSnS4 (Kesterite, Wurtzite) Nanocrystals	Yarur Villanueva F; Green PB; Qiu C; Ullah SR; Buenviaje K; Howe JY; Majewski MB; Wilson MWB;	34705409 CNSR
13	Sustainable chemical processing of flowing wastewater through microwave energy	Siddique F; Mirzaei A; Gonzalez-Cortes S; Slocombe D; Al-Megren HA; Xiao T; Rafiq MA; Edwards PP;	34474383 PHYSICS
14	Tuning the redox potential of the primary electron donor in bacterial reaction centers by manganese binding and light-induced structural changes.	Deshmukh SS, Kálmán L	32777306 PHYSICS
15	Biosynthesis of Alkylcitric Acids in Aspergillus niger Involves Both Co-localized and Unlinked Genes.	Palys S, Pham TTM, Tsang A	32695080 CSFG
16	Bound detergent molecules in bacterial reaction centers facilitate detection of tetryl explosive.	Modafferi D, Zazubovich V, Kálmán L	32632533 PHYSICS
17	Transcriptomic analysis suggests the inhibition of DNA damage repair in green alga Raphidocelis subcapitata exposed to roxithromycin.	Guo J, Bai Y, Chen Z, Mo J, Li Q, Sun H, Zhang Q	32505758 CHEMISTRY
18	Surface Response Based Modeling of Liposome Characteristics in a Periodic Disturbance Mixer.	López RR, Ocampo I, Sánchez LM, Alazzam A, Bergeron KF, Camacho-León S, Mounier C, Stiharu I, Nerguizian V	32106424 ENCS
19	Effects of a recombinant fibrolytic enzyme on fiber digestion, ruminal fermentation, nitrogen balance and total tract digestibility of heifers fed a high forage diet.	Ran T, Saleem AM, Shen Y, Ribeiro GO, Beauchemin KA, Tsang A, Yang W, McAllister TA	31251799 CSFG
20	Microbial Factories for the Production of Benzylisoquinoline Alkaloids.	Narcross L, Fossati E, Bourgeois L, Dueber JE, Martin VJJ	26775900 BIOLOGY
21	Characterization of two novel antimicrobial peptides from the cuticular extracts of the ant Trichomyrmex criniceps (Mayr), (Hymenoptera: Formicidae).	Bhagavathula N, Meedidoddi V, Bourque S, Vimaladevi R, Kesavakurup S, Selvadurai D, Shrivastava S, Krishnappa C	28346717 PERFORM
22	Structure-Guided Directed Evolution of Glycosidases: A Case Study in Engineering a Blood Group Antigen-Cleaving Enzyme.	Kwan DH	28935105 CSFG
23	A Combinatorial Approach To Study Cytochrome P450 Enzymes for De Novo Production of Steviol Glucosides in Baker's Yeast.	Gold ND, Fossati E, Hansen CC, DiFalco M, Douchin V, Martin VJJ	30474973 CSFG

Title:	Microbial Factories for the Production of Benzylisoquinoline Alkaloids.
Authors:	Narcross L, Fossati E, Bourgeois L, Dueber JE, Martin VJJ
Link:	https://www.ncbi.nlm.nih.gov/pubmed/26775900?dopt=Abstract
DOI:	10.1016/j.tibtech.2015.12.005
Publication:	Trends in biotechnology
Keywords:	aromatic amino acids; benzylisoquinoline alkaloids; biosecurity; dopamine; microbial synthesis; morphinans;
PMID:	26775900	Category:	Trends Biotechnol	Date Added:	2019-06-07
Dept Affiliation:	BIOLOGY 1 Department of Biology, Concordia University, Montréal, Québec H4B 1R6, Canada; Centre for Structural and Functional Genomics, Concordia University, Montréal, Québec H4B 1R6, Canada. 2 Department of Bioengineering, University of California, Berkeley, Berkeley, CA 94704, USA. 3 Department of Biology, Concordia University, Montréal, Québec H4B 1R6, Canada; Centre for Structural and Functional Genomics, Concordia University, Montréal, Québec H4B 1R6, Canada. Electronic address: vincent.martin@concordia.ca.

Description:

Microbial Factories for the Production of Benzylisoquinoline Alkaloids.

Trends Biotechnol. 2016 Mar;34(3):228-241

Authors: Narcross L, Fossati E, Bourgeois L, Dueber JE, Martin VJJ

Abstract

Benzylisoquinoline alkaloids (BIAs) are a family of ~2500 alkaloids with both potential and realized pharmaceutical value, including most notably the opiates such as codeine and morphine. Only a few BIAs accumulate readily in plants, which limits the pharmaceutical potential of the family. Shifting BIA production to microbial sources could provide a scalable and flexible source of these compounds in the future. This review details the current status of microbial BIA synthesis and derivatization, including rapid developments in the past 6 months culminating in the synthesis of opioids from glucose in a microbial host.

PMID: 26775900 [PubMed - indexed for MEDLINE]

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