Keyword search (4,163 papers available)

"carbohydrate" Keyword-tagged Publications:

Title Authors PubMed ID
1 Expansion of Auxiliary Activity Family 5 sequence space via biochemical characterization of six new copper radical oxidases Fong JK; Mathieu Y; Vo MT; Bellemare A; Tsang A; Brumer H; 38953370
CSFG
2 Identification of Genes Involved in the Degradation of Lignocellulose Using Comparative Transcriptomics Gruninger RJ; Tsang A; McAllister TA; 37149538
CSFG
3 Xylan glucuronic acid side chains fix suberin-like aliphatic compounds to wood cell walls Derba-Maceluch M; Mitra M; Hedenström M; Liu X; Gandla ML; Barbut FR; Abreu IN; Donev EN; Urbancsok J; Moritz T; Jönsson LJ; Tsang A; Powlowski J; Master ER; Mellerowicz EJ; 36600379
CSFG
4 On the Origin of Sugar Handedness: Facts, Hypotheses and Missing Links-A Review Martínez RF; Cuccia LA; Viedma C; Cintas P; 35796896
CHEMBIOCHEM
5 Editorial: The Effect of Carbohydrate Restriction on Cancer and Metabolic Syndrome Elisia I; Santosa S; Popovich DG; Krystal G; 35237644
HKAP
6 Screening of novel fungal Carbohydrate Esterase family 1 enzymes identifies three novel dual feruloyl/acetyl xylan esterases Dilokpimol A; Verkerk B; Li X; Bellemare A; Lavallee M; Frommhagen M; Nørmølle Underlin E; Kabel MA; Powlowski J; Tsang A; de Vries RP; 35187647
CSFG
7 Resources and Methods for Engineering "Designer" Glycan-Binding Proteins. Warkentin R, Kwan DH 33450899
CHEMBIOCHEM
8 Transcriptome and exoproteome analysis of utilization of plant-derived biomass by Myceliophthora thermophila. Kolbusz MA, Di Falco M, Ishmael N, Marqueteau S, Moisan MC, Baptista CDS, Powlowski J, Tsang A 24881579
BIOLOGY
9 Evaluation of secretome of highly efficient lignocellulolytic Penicillium sp. Dal 5 isolated from rhizosphere of conifers. Rai R, Kaur B, Singh S, Di Falco M, Tsang A, Chadha BS 27341464
CSFG
10 Identification of Genes Involved in the Degradation of Lignocellulose Using Comparative Transcriptomics. Gruninger RJ, Reid I, Forster RJ, Tsang A, McAllister TA 28417376
CSFG
11 Discovery and characterization of family 39 glycoside hydrolases from rumen anaerobic fungi with polyspecific activity on rare arabinosyl substrates. Jones DR, Uddin MS, Gruninger RJ, Pham TTM, Thomas D, Boraston AB, Briggs J, Pluvinage B, McAllister TA, Forster RJ, Tsang A, Selinger LB, Abbott DW 28588026
CSFG
12 Identification of novel enzymes to enhance the ruminal digestion of barley straw Badhan A; Ribeiro GO; Jones DR; Wang Y; Abbott DW; Di Falco M; Tsang A; McAllister TA; 29621684
CSFG
13 Saccharification efficiencies of multi-enzyme complexes produced by aerobic fungi. Badhan A, Huang J, Wang Y, Abbott DW, Di Falco M, Tsang A, McAllister T 29803771
CSFG
14 Application of Transcriptomics to Compare the Carbohydrate Active Enzymes That Are Expressed by Diverse Genera of Anaerobic Fungi to Degrade Plant Cell Wall Carbohydrates. Gruninger RJ, Nguyen TTM, Reid ID, Yanke JL, Wang P, Abbott DW, Tsang A, McAllister T 30061875
CSFG

 

Title:Resources and Methods for Engineering "Designer" Glycan-Binding Proteins.
Authors:Warkentin RKwan DH
Link:https://www.ncbi.nlm.nih.gov/pubmed/33450899
DOI:10.3390/molecules26020380
Publication:Molecules (Basel, Switzerland)
Keywords:carbohydratesdirected evolutionglycan immobilizationglycan-binding proteinglycansglycobiologylectinsprotein engineering
PMID:33450899 Category:Molecules Date Added:2021-01-17
Dept Affiliation: CHEMBIOCHEM
1 Department of Biology, Centre for Applied Synthetic Biology, and Centre for Structural and Functional Genomics, Concordia University, 7141 Sherbrooke Street West, Montreal, QC H4B 1R6, Canada.
2 PROTEO, Quebec Network for Research on Protein Function, Structure, and Engineering, Quebec City, QC G1V 0A6, Canada.
3 Department of Chemistry and Biochemistry, Concordia University, 7141 Sherbrooke Street West, Montreal, QC H4B 1R6, Canada.

Description:

Resources and Methods for Engineering "Designer" Glycan-Binding Proteins.

Molecules. 2021 Jan 13; 26(2):

Authors: Warkentin R, Kwan DH

Abstract

This review provides information on available methods for engineering glycan-binding proteins (GBP). Glycans are involved in a variety of physiological functions and are found in all domains of life and viruses. Due to their wide range of functions, GBPs have been developed with diagnostic, therapeutic, and biotechnological applications. The development of GBPs has traditionally been hindered by a lack of available glycan targets and sensitive and selective protein scaffolds; however, recent advances in glycobiology have largely overcome these challenges. Here we provide information on how to approach the design of novel "designer" GBPs, starting from the protein scaffold to the mutagenesis methods, selection, and characterization of the GBPs.

PMID: 33450899 [PubMed - as supplied by publisher]





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