Keyword search (4,163 papers available)

"Shizgal P" Authored Publications:

Title Authors PubMed ID
1 Discriminative properties of rewarding electrical brain stimulation Pacheco-Gomez BL; Zepeda-Ruiz WA; Velazquez-Lopez D; Shizgal P; Velazquez-Martinez DN; 40015584
CSBN
2 Does phasic dopamine release cause policy updates? Carter F; Cossette MP; Trujillo-Pisanty I; Pallikaras V; Breton YA; Conover K; Caplan J; Solis P; Voisard J; Yaksich A; Shizgal P; 38039083
PSYCHOLOGY
3 Dopamine and Beyond: Implications of Psychophysical Studies of Intracranial Self-Stimulation for the Treatment of Depression Pallikaras V; Shizgal P; 36009115
PSYCHOLOGY
4 The Convergence Model of Brain Reward Circuitry: Implications for Relief of Treatment-Resistant Depression by Deep-Brain Stimulation of the Medial Forebrain Bundle Pallikaras V; Shizgal P; 35431828
PSYCHOLOGY
5 The trade-off between pulse duration and power in optical excitation of midbrain dopamine neurons approximates Bloch's law Pallikaras V; Carter F; Velazquez-Martinez DN; Arvanitogiannis A; Shizgal P; 34864162
PSYCHOLOGY
6 Dopamine neurons do not constitute an obligatory stage in the final common path for the evaluation and pursuit of brain stimulation reward. Trujillo-Pisanty I, Conover K, Solis P, Palacios D, Shizgal P 32502210
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7 The priming effect of food persists following blockade of dopamine receptors. Evangelista C, Hantson A, Shams WM, Almey A, Pileggi M, Voisard JR, Boulos V, Al-Qadri Y, Gonzalez Cautela BV, Zhou FX, Duchemin J, Habrich A, Tito N, Koumrouyan RA, Patel S, Lorenc V, Gagne C, El Oufi K, Shizgal P, Brake WG 31350860
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8 Learning to use past evidence in a sophisticated world model. Ahilan S, Solomon RB, Breton YA, Conover K, Niyogi RK, Shizgal P, Dayan P 31233559
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9 Ventral Midbrain NMDA Receptor Blockade: From Enhanced Reward and Dopamine Inactivation. Hernandez G, Cossette MP, Shizgal P, Rompré PP 27616984
PSYCHOLOGY
10 Valuation of opportunity costs by rats working for rewarding electrical brain stimulation. Solomon RB, Conover K, Shizgal P 28841663
PSYCHOLOGY
11 17β-estradiol locally increases phasic dopamine release in the dorsal striatum. Shams WM, Cossette MP, Shizgal P, Brake WG 29175028
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12 Some work and some play: microscopic and macroscopic approaches to labor and leisure. Niyogi RK, Shizgal P, Dayan P 25474151
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13 Robust optical fiber patch-cords for in vivo optogenetic experiments in rats. Trujillo-Pisanty I, Sanio C, Chaudhri N, Shizgal P 26150997
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14 The neural substrates for the rewarding and dopamine-releasing effects of medial forebrain bundle stimulation have partially discrepant frequency responses. Cossette MP, Conover K, Shizgal P 26477378
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15 The Effects of Electrical and Optical Stimulation of Midbrain Dopaminergic Neurons on Rat 50-kHz Ultrasonic Vocalizations. Scardochio T, Trujillo-Pisanty I, Conover K, Shizgal P, Clarke PB 26696851
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Title:17β-estradiol locally increases phasic dopamine release in the dorsal striatum.
Authors:Shams WM,  Cossette MP,  Shizgal P,  Brake WG
Link:https://www.ncbi.nlm.nih.gov/pubmed/29175028?dopt=Abstract
DOI:10.1016/j.neulet.2017.11.039
Publication:Neuroscience letters
Keywords:Estrogens;  Fast-scan cyclic voltammetry; 
PMID:29175028 Category:Neurosci Lett Date Added:2019-06-20
Dept Affiliation: CSBN
1 Department of Psychology, Centre for Studies in Behavioral Neurobiology, Concordia University, Montreal, Quebec, H4B 1R6, Canada. Electronic address: waqqas.shams@gmail.com.
2 Department of Psychology, Centre for Studies in Behavioral Neurobiology, Concordia University, Montreal, Quebec, H4B 1R6, Canada. Electronic address: mpy_cossette@hotmail.com.
3 Department of Psychology, Centre for Studies in Behavioral Neurobiology, Concordia University, Montreal, Quebec, H4B 1R6, Canada. Electronic address: peter.shizgal@concordia.ca.
4 Department of Psychology, Centre for Studies in Behavioral Neurobiology, Concordia University, Montreal, Quebec, H4B 1R6, Canada. Electronic address: wayne.brake@concordia.ca.

Description:

17ß-estradiol locally increases phasic dopamine release in the dorsal striatum.

Neurosci Lett. 2018 02 05;665:29-32

Authors: Shams WM, Cossette MP, Shizgal P, Brake WG

Abstract

Studies using in vivo microdialysis have shown that 17ß-estradiol (E2) increases dopamine (DA) transmission in the dorsal striatum. Both systemic administration of E2 and local infusion into the dorsal striatum rapidly enhance amphetamine-induced DA release. However, it is not known to what degree these effects reflect tonic and/or phasic DA release. It was hypothesized that E2 acts directly within the DS to rapidly increase phasic DA transmission. In urethane-anesthetized (1.5mL/kg) female rats, we used fast-scan cyclic voltammetry to study the effects of E2 on phasic, electrically-evoked release of DA in the dorsal striatum. Rats were ovariectomized and implanted with a silastic tube containing 5% E2 in cholesterol, previously shown to mimic low physiological serum concentrations of~20-25pg/mL. DA release was evoked every 1min by delivering biphasic electrical stimulation in the substantia nigra. Local infusions of E2 (244.8pg/µl) into the dorsal striatum increased the amplitude of the electrically evoked DA transients. Behaviorally significant stimuli and events trigger phasic release of DA. The present findings predict that E2 would boost such signaling in behaving subjects.

PMID: 29175028 [PubMed - indexed for MEDLINE]




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