Keyword search (4,163 papers available)

"Lussier M" Authored Publications:

Title Authors PubMed ID
1 The effect of hearing ability on dual-task performance following multi-domain training in older adults with mild cognitive impairment: findings from the SYNERGIC trial Downey RI; Petersen BJ; Mohanathas N; Campos JL; Montero-Odasso M; Bherer L; Pichora-Fuller MK; Bray NW; Burhan AM; Camicioli R; Fraser S; Liu-Ambrose T; Lussier M; Middleton LE; Pieruccini-Faria F; Phillips NA; Li KZH; 41694460
SOH
2 Clinical Manifestations Gagnon C; Montero-Odasso M; Zou G; Speechley MR; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Bray NW; Li K; Fraser S; Pieruccini-Faria F; Burhan AM; Berryman N; Lussier M; Son S; Shoemaker JK; Bherer L; 41447475
CONCORDIA
3 Synergistic effects of exercise, cognitive training and vitamin D on gait performance and falls in mild cognitive impairment-secondary outcomes from the SYNERGIC trial Pieruccini-Faria F; Son S; Zou G; Almeida QJ; Middleton LE; Bray NW; Lussier M; Shoemaker JK; Speechley M; Liu-Ambrose T; Burhan AM; Camicioli R; Li KZH; Fraser S; Berryman N; Bherer L; Montero-Odasso M; 40966614
SOH
4 At-home computerized executive-function training to improve cognition and mobility in normal-hearing adults and older hearing aid users: a multi-centre, single-blinded randomized controlled trial Downey R; Gagné N; Mohanathas N; Campos JL; Pichora-Fuller KM; Bherer L; Lussier M; Phillips NA; Wittich W; St-Onge N; Gagné JP; Li K; 37864139
PERFORM
5 Effects of Exercise Alone or Combined With Cognitive Training and Vitamin D Supplementation to Improve Cognition in Adults With Mild Cognitive Impairment: A Randomized Clinical Trial Montero-Odasso M; Zou G; Speechley M; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Bray NW; Li KZH; Fraser S; Pieruccini-Faria F; Berryman N; Lussier M; Shoemaker JK; Son S; Bherer L; 37471089
PERFORM
6 Multiple routes to help you roam: A comparison of training interventions to improve cognitive-motor dual-tasking in healthy older adults Downey R; Bherer L; Pothier K; Vrinceanu T; Intzandt B; Berryman N; Lussier M; Vincent T; Karelis AD; Nigam A; Vu TTM; Bosquet L; Li KZH; 36408116
PERFORM
7 A comparison of the effect of physical activity and cognitive training on dual-task performance in older adults Vrinceanu T; Blanchette CA; Intzandt B; Lussier M; Pothier K; Vu TTM; Nigam A; Bosquet L; Karelis AD; Li KZH; Berryman N; Bherer L; 34865009
PERFORM
8 Assessment of the Relationship Between Executive Function and Cardiorespiratory Fitness in Healthy Older Adults Predovan D; Berryman N; Lussier M; Comte F; Vu TTM; Villalpando JM; Bherer L; 34803824
PERFORM
9 A comparison of physical exercise and cognitive training interventions to improve determinants of functional mobility in healthy older adults Pothier K; Vrinceanu T; Intzandt B; Bosquet L; Karelis AD; Lussier M; Vu TTM; Nigam A; Li KZH; Berryman N; Bherer L; 33774144
PERFORM
10 Synergistic effects of cognitive training and physical exercise on dual-task performance in older adults Bherer L; Gagnon C; Langeard A; Lussier M; Desjardins-Crépeau L; Berryman N; Bosquet L; Vu TTM; Fraser S; Li KZH; Kramer AF; 32803232
PERFORM
11 Ageism and COVID-19: What does our society's response say about us? Fraser S, Lagacé M, Bongué B, Ndeye N, Guyot J, Bechard L, Garcia L, Taler V, CCNA Social Inclusion and Stigma Working Group, Adam S, Beaulieu M, Bergeron CD, Boudjemadi V, Desmette D, Donizzetti AR, Éthier S, Garon S, Gillis M, Levasseur M, Lortie-Lussier M, Marier P, Robitaille A, Sawchuk K, Lafontaine C, Tougas F 32377666
PSYCHOLOGY
12 Effects of Dance/Movement Training vs. Aerobic Exercise Training on cognition, physical fitness and quality of life in older adults: A randomized controlled trial. Esmail A, Vrinceanu T, Lussier M, Predovan D, Berryman N, Houle J, Karelis A, Grenier S, Minh Vu TT, Villalpando JM, Bherer L 31987547
PERFORM
13 SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment. Montero-Odasso M, Almeida QJ, Burhan AM, Camicioli R, Doyon J, Fraser S, Li K, Liu-Ambrose T, Middleton L, Muir-Hunter S, McIlroy W, Morais JA, Pieruccini-Faria F, Shoemaker K, Speechley M, Vasudev A, Zou GY, Berryman N, Lussier M, Vanderhaeghe L, Bherer L 29661156
PERFORM
14 Switching Ability Mediates the Age-Related Difference in Timed Up and Go Performance. Langeard A, Houdeib R, Saillant K, Kaushal N, Lussier M, Bherer L 30909238
PSYCHOLOGY
15 Limited Benefits of Heterogeneous Dual-Task Training on Transfer Effects in Older Adults. Lussier M, Brouillard P, Bherer L 26603017
PERFORM
16 Specific transfer effects following variable priority dual-task training in older adults. Lussier M, Bugaiska A, Bherer L 27372514
PERFORM
17 A comparison of the impact of physical exercise, cognitive training and combined intervention on spontaneous walking speed in older adults. Pothier K, Gagnon C, Fraser SA, Lussier M, Desjardins-Crépeau L, Berryman N, Kergoat MJ, Vu TTM, Li KZH, Bosquet L, Bherer L 29235076
PERFORM

 

Title:The effect of hearing ability on dual-task performance following multi-domain training in older adults with mild cognitive impairment: findings from the SYNERGIC trial
Authors:Downey RIPetersen BJMohanathas NCampos JLMontero-Odasso MBherer LPichora-Fuller MKBray NWBurhan AMCamicioli RFraser SLiu-Ambrose TLussier MMiddleton LEPieruccini-Faria FPhillips NALi KZH
Link:https://pubmed.ncbi.nlm.nih.gov/41694460/
DOI:10.3389/fnagi.2025.1716733
Publication:Frontiers in aging neuroscience
Keywords:cognitive trainingdual-taskexercisegaithearing lossmild cognitive impairmentmulti-domain training
PMID:41694460 Category: Date Added:2026-02-16
Dept Affiliation: SOH
1 Department of Psychology/Centre for Research in Human Development, Concordia University, Montréal, QC, Canada.
2 School of Health, Concordia University, Montréal, QC, Canada.
3 Department of Psychology, University of Toronto, Toronto, ON, Canada.
4 KITE-Toronto Rehabilitation Institute, University Health Network, Toronto, ON, Canada.
5 Department of Medicine, Division of Geriatric Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
6 Gait and Brain Lab, Parkwood Institute, Lawson Health Research Institute, London, ON, Canada.
7 Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
8 Département de Médecine, Université de Montréal, Montréal, QC, Canada.
9 Centre de Recherche de l'Institut de Cardiologie de Montréal, Montréal, QC, Canada.
10 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, QC, Canada.
11 Recovery and Performance Lab, Division of Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada.
12 Ontario Shores Centre for Mental Health Sciences, Whitby, ON, Canada.
13 Division of Geriatric Psychiatry, Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
14 Department of Medicine (Neurology), University of Alberta, Edmonton, AB, Canada.
15 Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB, Canada.
16 Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada.
17 The Centre for Aging SMART, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.
18 Djavad Mowafaghian Centre for Brain Health, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.
19 Department of Kinesiology and Health Sciences, University of Waterloo, ON, Canada.
20 Schlegel-UW Research Institute for Aging, Waterloo, ON, Canada.

Description:

Background: Hearing loss is one of the largest potentially modifiable risk factors for dementia and is linked with poor cognitive-motor dual-task performance (e.g., walking while performing a cognitive task). Hearing loss is more prevalent and severe in males, whereas dementia is more prevalent in females. Physical exercise and cognitive interventions appear promising in improving dual-tasking in older adults; however, it is currently unclear whether hearing ability affects training efficacy on dual-task outcomes in older adults with mild cognitive impairment (MCI), and whether sex influences this effect.

Objective: The primary aim of this study was to examine whether hearing ability affects dual-task performance at baseline and after training in individuals with MCI, and whether sex further influences these relationships, irrespective of intervention arm.

Methods: Secondary data was analysed from 75 participants with MCI (Mage = 73.66 ± 6.67) enrolled in the SYNERGIC trial. Hearing ability was assessed using self-report and behavioral measures. Participants completed a 20-week intervention: (1) Exercise (aerobic-resistance exercise + sham cognitive training; n = 31), (2) Multi-Domain Training (aerobic-resistance exercise + cognitive training; n = 32), or (3) Placebo Training (balance and toning exercises + sham cognitive training; n = 12). Primary outcomes included dual-task gait and cognitive performance.

Results: At baseline, poorer hearing predicted worse dual-task performance, particularly in males. Dual-task gait variability significantly improved following Multi-Domain Training in participants with a greater degree of self-reported hearing complaints. Sex-stratified analyses revealed that females with more hearing complaints improved more across all interventions, while in the Multi-Domain group, males with poorer objective hearing and females with better hearing showed the greatest gains. Additionally, in those with poorer hearing, lower cognitive scores (MoCA) predicted greater improvements after Multi-Domain Training, but a decline after Placebo Training.

Conclusion: Hearing ability, sex, and cognitive status appear to interact to influence the effects of exercise and cognitive training on dual-task performance in older adults with MCI. Multi-Domain Training appears particularly beneficial for those with hearing loss (who are male and/or have lower cognitive status), highlighting the need for personalized interventions to preserve function and slow decline in this at-risk population.

Clinical trial registration: https://www.clinicaltrials.gov/ct2/show/NCT02808676, NCT02808676.





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