Keyword search (4,163 papers available)

"Das S" Authored Publications:

Title Authors PubMed ID
1 Basic Science and Pathogenesis Borrie MJ; Phillips NA; Best S; Anastasiou-Ventura P; Aydogan T; Beaudoin C; Beuk J; Celotto I; Cole L; Das S; Fogarty J; Fouquet C; Gnassi L; Henri-Bellemare C; Pilon R; Sands J; Stirbu A; Truemner J; Chan S; Tucker A; Gajraj J; Bhangu J; Chertkow H; 41435411
CONCORDIA
2 Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA) Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; Bélanger N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello C; Cynader M; Dang-Vu T; Das S; Dixon RA; Ducharme S; Einstein G; Evans AC; Fahnestock M; Feldman H; Ferland G; Finger E; Fisk JD; Fogarty J; Fon E; Gan-Or Z; Gauthier S; Greenwood C; Henri-Bellemare C; Herrmann N; Hogan DB; Hsiung R; Itzhak I; Jacklin K; Lanctôt K; Lim A; MacKenzie I; Masellis M; Maxwell C; McAiney C; McGilton K; McLaurin J; Mihailidis A; Mohades Z; Montero-Odasso M; Morgan D; Naglie G; Nygaard H; O' Connell M; Petersen R; Pilon R; Rajah MN; Rapoport M; Roach P; Robillard JM; Rogaeva E; Rosa-Neto P; Rylett J; Sadavoy J; St George-Hyslop P; Seitz D; Smith E; Stefanovic B; Vedel I; Walker JD; Wellington C; Whitehead V; Wittich W; 39636028
HKAP
3 Comparative genomic analysis of thermophilic fungi reveals convergent evolutionary adaptations and gene losses Steindorff AS; Aguilar-Pontes MV; Robinson AJ; Andreopoulos B; LaButti K; Kuo A; Mondo S; Riley R; Otillar R; Haridas S; Lipzen A; Grimwood J; Schmutz J; Clum A; Reid ID; Moisan MC; Butler G; Nguyen TTM; Dewar K; Conant G; Drula E; Henrissat B; Hansel C; Singer S; Hutchinson MI; de Vries RP; Natvig DO; Powell AJ; Tsang A; Grigoriev IV; 39266695
CSFG
4 A chloromethyl-triazole fluorescent chemosensor for O6-methylguanine DNA methyltransferase Ayan S; Rotaru AM; Kaye EG; Juneau G; Das S; Wilds CJ; Beharry AA; 38502038
CHEMBIOCHEM
5 Data and Tools Integration in the Canadian Open Neuroscience Platform Poline JB; Das S; Glatard T; Madjar C; Dickie EW; Lecours X; Beaudry T; Beck N; Behan B; Brown ST; Bujold D; Beauvais M; Caron B; Czech C; Dharsee M; Dugré M; Evans K; Gee T; Ippoliti G; Kiar G; Knoppers BM; Kuehn T; Le D; Lo D; Mazaheri M; MacFarlane D; Muja N; O' Brien EA; O' Callaghan L; Paiva S; Park P; Quesnel D; Rabelais H; Rioux P; Legault M; Tremblay-Mercier J; Rotenberg D; Stone J; Strauss T; Zaytseva K; Zhou J; Duchesne S; Khan AR; Hill S; Evans AC; 37024500
ENCS
6 A Simulation Toolkit for Testing the Sensitivity and Accuracy of Corticometry Pipelines OmidYeganeh M; Khalili-Mahani N; Bermudez P; Ross A; Lepage C; Vincent RD; Jeon S; Lewis LB; Das S; Zijdenbos AP; Rioux P; Adalat R; Van Eede MC; Evans AC; 34381348
PERFORM
7 The Comprehensive Assessment of Neurodegeneration and Dementia: Canadian Cohort Study. Chertkow H, Borrie M, Whitehead V, Black SE, Feldman HH, Gauthier S, Hogan DB, Masellis M, McGilton K, Rockwood K, Tierney MC, Andrew M, Hsiung GR, Camicioli R, Smith EE, Fogarty J, Lindsay J, Best S, Evans A, Das S, Mohaddes Z, Pilon R, Poirier J, Phillips NA, MacNamara E, Dixon RA, Duchesne S, MacKenzie I, Rylett RJ 31309917
PSYCHOLOGY
8 Cyberinfrastructure for Open Science at the Montreal Neurological Institute. Das S, Glatard T, Rogers C, Saigle J, Paiva S, MacIntyre L, Safi-Harab M, Rousseau ME, Stirling J, Khalili-Mahani N, MacFarlane D, Kostopoulos P, Rioux P, Madjar C, Lecours-Boucher X, Vanamala S, Adalat R, Mohaddes Z, Fonov VS, Milot S, Leppert I, Degroot C, Durcan TM, Campbell T, Moreau J, Dagher A, Collins DL, Karamchandani J, Bar-Or A, Fon EA, Hoge R, Baillet S, Rouleau G, Evans AC 28111547
IMAGING
9 Best practices in data analysis and sharing in neuroimaging using MRI. Nichols TE, Das S, Eickhoff SB, Evans AC, Glatard T, Hanke M, Kriegeskorte N, Milham MP, Poldrack RA, Poline JB, Proal E, Thirion B, Van Essen DC, White T, Yeo BT 28230846
IMAGING
10 Flavanone glycosides inhibit β-site amyloid precursor protein cleaving enzyme 1 and cholinesterase and reduce Aβ aggregation in the amyloidogenic pathway. Ali MY, Jannat S, Edraki N, Das S, Chang WK, Kim HC, Park SK, Chang MS 31194956
BIOLOGY
11 Investigation of inter- and intraspecies variation through genome sequencing of Aspergillus section Nigri. Vesth TC, Nybo JL, Theobald S, Frisvad JC, Larsen TO, Nielsen KF, Hoof JB, Brandl J, Salamov A, Riley R, Gladden JM, Phatale P, Nielsen MT, Lyhne EK, Kogle ME, Strasser K, McDonnell E, Barry K, Clum A, Chen C, LaButti K, Haridas S, Nolan M, Sandor L, Kuo A, Lipzen A, Hainaut M, Drula E, Tsang A, Magnuson JK, Henrissat B, Wiebenga A, Simmons BA, Mäkelä MR, de Vries RP, Grigoriev IV, Mortensen UH, Baker SE, Andersen MR 30349117
CSFG
12 Boutiques: a flexible framework to integrate command-line applications in computing platforms. Glatard T, Kiar G, Aumentado-Armstrong T, Beck N, Bellec P, Bernard R, Bonnet A, Brown ST, Camarasu-Pop S, Cervenansky F, Das S, Ferreira da Silva R, Flandin G, Girard P, Gorgolewski KJ, Guttmann CRG, Hayot-Sasson V, Quirion PO, Rioux P, Rousseau MÉ, Evans AC 29718199
ENCS

 

Title:Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA)
Authors:Chertkow HPhillips NRockwood KAnderson NAndrew MKBartha RBeaudoin CBélanger NBellec PBelleville SBergman HBest SBethell JBherer LBlack SBorrie MCamicioli RCarrier JCashman NChan SCrowshoe LCuello CCynader MDang-Vu TDas SDixon RADucharme SEinstein GEvans ACFahnestock MFeldman HFerland GFinger EFisk JDFogarty JFon EGan-Or ZGauthier SGreenwood CHenri-Bellemare CHerrmann NHogan DBHsiung RItzhak IJacklin KLanctôt KLim AMacKenzie IMasellis MMaxwell CMcAiney CMcGilton KMcLaurin JMihailidis AMohades ZMontero-Odasso MMorgan DNaglie GNygaard HO'Connell MPetersen RPilon RRajah MNRapoport MRoach PRobillard JMRogaeva ERosa-Neto PRylett JSadavoy JSt George-Hyslop PSeitz DSmith EStefanovic BVedel IWalker JDWellington CWhitehead VWittich W
Link:https://pubmed.ncbi.nlm.nih.gov/39636028/
DOI:10.1177/13872877241290990
Publication:Journal of Alzheimer s disease : JAD
Keywords:Alzheimer's diseasecohortdementiapreventionresearch plansexsynergy
PMID:39636028 Category: Date Added:2024-12-05
Dept Affiliation: HKAP
1 Lady Davis Institute for Medical Research, Montréal, Québec, Canada.
2 Department of Medicine (Neurology), University of Toronto, Toronto, Ontario, Canada.
3 Rotman Research Institute, Baycrest Academy for Research & Education, Toronto, Ontario, Canada.
4 Affiliate Member, Department of Neurology and Neurosurgery, McGill University, Montréal, Québec, Canada.
5 Department of Psychology, Concordia University, Montréal, Québec, Canada.
6 Division of Geriatric Medicine, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
7 Department of Psychology, University of Toronto, Toronto, Ontario, Canada.
8 Division of Geriatric Medicine, Department of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.
9 Department of Psychiatry, University of Western Ontario, London, Ontario, Canada.
10 The Brain and Mind Institute, University of Western Ontario, London, Ontario, Canada.
11 McGill Centre for Integrative Neuroscience, Montréal, Québec, Canada.
12 Centre de recherche IUGM, Institut universitaire de gériatrie de Montréal, Montréal, Québec, Canada.
13 Département de psychologie, Université de Montréal, Montréal, Québec, Canada.
14 Department of Medicine (Geriatrics) and Oncology, McGill University, Montréal, Québec, Canada.
15 Department of Family Medicine, McGill University, Montréal, Québec, Canada.
16 Lawson Health Research Institute, London, Ontario, Canada.
17 KITE-Toronto Rehabilitation Institute, University Health Network, Toronto, Canada.
18 Département de médecine, Université de Montréal, Montréal, Québec, Canada.
19 Institut de Cardiologie de Montréal-Montreal Heart Institute, Montréal, Québec, Canada.
20 Sunnybrook Research Institute, Toronto, Ontario, Canada.
21 Department of Medicine (Neurology), University of Toronto, Toronto, Ontario, Canada; Sunnybrook Research Institute, Toronto, Ontario, Canada.
22 Schulich School of Medicine & Dentistry, Department of Medicine and Division of Geriatric Medicine, University of Western Ontario, London, Ontario, Canada.
23 Schulich School of Medicine & Dentistry, Department of Medicine and Division of Geriatric Medicine, University of Western Ontario, London, Ontario, Canada; Lawson Health Research Institute, London, Ontario, Canada.
24 Department of Medicine, University of Alberta, Edmonton, Alberta, Canada. Neuroscience and Mental Health Institute, Edmonton, Alberta, Canada.
25 Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
26 Neuroscience and Mental Health Institute, Edmonton, Alberta, Canada.
27 Center for Advanced Research in Sleep Medicine (CARSM), Hôpital du Sacré-Coeur de Montréal, Montréal, Québec, Canada.
28 Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
29 Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada.
30 Rotman Research Institute, Baycrest Hospital, Toronto, Ontario, Canada.
31 Department of Family Medicine & Indigenous, Local and Global Health Office, University of Calgary, Calgary, Alberta, Canada.
32 Department of Neurology and Neurosurgery, McGill University, Montréal, Qikb1uébec, Canada.
33 Department of Pharmacology & Therapeutics, McGill Univers

Description:

The Canadian Consortium on Neurodegeneration in Aging (CCNA) was created by the Canadian federal government through its health research funding agency, the Canadian Institutes for Health Research (CIHR), in 2014, as a response to the G7 initiative to fight dementia. Two five-year funding cycles (2014-2019; 2019-2024) have occurred following peer review, and a third cycle (Phase 3) has just begun. A unique construct was mandated, consisting of 20 national teams in Phase I and 19 teams in Phase II (with research topics spanning from basic to clinical science to health resource systems) along with cross-cutting programs to support them. Responding to the needs of researchers within the CCNA teams, a unique sample of 1173 deeply phenotyped patients with various forms of dementia was accrued and studied over eight years (COMPASS-ND). In the second phase of funding (2019-2024), a national dementia prevention program (CAN-THUMBS UP) was set up. In a short time, this prevention program became a member of the World Wide FINGERS prevention consortium. In this article, the challenges, successes, and impacts of CCNA in Canada and internationally are discussed. Short-term deliverables have occurred, along with considerable promise of impacts in the longer term. The creation of synergy, networking, capacity building, engagement of people with lived experience, and economies of scale have contributed to the considerable success of CCNA by all measures. CCNA is evidence that an organized "centrally-organized" approach to dementia research can catalyze important progress nationally and yield significant and measurable results.





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