Keyword search (4,163 papers available)

"Amir S" Authored Publications:

Title Authors PubMed ID
1 Disruptive effects of d-amphetamine on conditioned sexual inhibition in the male rat Germé K; Persad D; Petit-Robinson J; Amir S; Pfaus JG; 40232387
PSYCHOLOGY
2 Effects of chronodisruption and alcohol consumption on gene expression in reward-related brain areas in female rats Meyer C; Schoettner K; Amir S; 39624490
PSYCHOLOGY
3 The effects of circadian desynchronization on alcohol consumption and affective behavior during alcohol abstinence in female rats Meyer C; Schoettner K; Amir S; 36620855
CSBN
4 Characterization of Affective Behaviors and Motor Functions in Mice With a Striatal-Specific Deletion of Bmal1 and Per2 Schoettner K; Alonso M; Button M; Goldfarb C; Herrera J; Quteishat N; Meyer C; Bergdahl A; Amir S; 35755440
HKAP
5 Thermoregulatory significance of immobility in the forced swim test Nadeau BG; Marchant EG; Amir S; Mistlberger RE; 35065081
PSYCHOLOGY
6 Bmal1 in the striatum influences alcohol intake in a sexually dimorphic manner de Zavalia N; Schoettner K; Goldsmith JA; Solis P; Ferraro S; Parent G; Amir S; 34702951
PSYCHOLOGY
7 In utero Exposure to Valproic-Acid Alters Circadian Organisation and Clock-Gene Expression: Implications for Autism Spectrum Disorders Ferraro S; de Zavalia N; Belforte N; Amir S; 34650409
CSBN
8 The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4. Pathak SS, Liu D, Li T, de Zavalia N, Zhu L, Li J, Karthikeyan R, Alain T, Liu AC, Storch KF, Kaufman RJ, Jin VX, Amir S, Sonenberg N, Cao R 31522764
CSBN
9 Effects of bilateral anterior agranular insula lesions on food anticipatory activity in rats. Gavrila AM, Hood S, Robinson B, Amir S 28594962
CSBN
10 Circadian Rhythms in Regulation of Brain Processes and Role in Psychiatric Disorders. Pantazopoulos H, Gamble K, Stork O, Amir S 29887881
PSYCHOLOGY
11 Mapping the co-localization of the circadian proteins PER2 and BMAL1 with enkephalin and substance P throughout the rodent forebrain. Frederick A, Goldsmith J, de Zavalia N, Amir S 28423013
BIOLOGY
12 Comprehensive mapping of regional expression of the clock protein PERIOD2 in rat forebrain across the 24-h day. Harbour VL, Weigl Y, Robinson B, Amir S 24124556
PSYCHOLOGY
13 Phase differences in expression of circadian clock genes in the central nucleus of the amygdala, dentate gyrus, and suprachiasmatic nucleus in the rat. Harbour VL, Weigl Y, Robinson B, Amir S 25068868
PSYCHOLOGY
14 Diurnal influences on electrophysiological oscillations and coupling in the dorsal striatum and cerebellar cortex of the anesthetized rat. Frederick A, Bourget-Murray J, Chapman CA, Amir S, Courtemanche R 25309348
BIOLOGY
15 Stress-induced changes in the expression of the clock protein PERIOD1 in the rat limbic forebrain and hypothalamus: role of stress type, time of day, and predictability. Al-Safadi S, Al-Safadi A, Branchaud M, Rutherford S, Dayanandan A, Robinson B, Amir S 25338089
CSBN
16 Light-regulated translational control of circadian behavior by eIF4E phosphorylation. Cao R, Gkogkas CG, de Zavalia N, Blum ID, Yanagiya A, Tsukumo Y, Xu H, Lee C, Storch KF, Liu AC, Amir S, Sonenberg N 25915475
CSBN
17 Glucocorticoids and Stress-Induced Changes in the Expression of PERIOD1 in the Rat Forebrain. Al-Safadi S, Branchaud M, Rutherford S, Amir S 26075608
CSBN
18 Circadian Rhythms and Psychopathology: From Models of Depression to Rhythms in Clock Gene Expression and Back Again. Verwey M, Al-Safadi S, Amir S 26195175
PSYCHOLOGY
19 From genes to chronotypes: the influence of circadian clock genes on our daily patterns of sleep and wakefulness. Verwey M, Amir S 27275497
CSBN
20 Exploring the role of locomotor sensitization in the circadian food entrainment pathway. Opiol H, de Zavalia N, Delorme T, Solis P, Rutherford S, Shalev U, Amir S 28301599
PSYCHOLOGY
21 Individual differences in circadian locomotor parameters correlate with anxiety- and depression-like behavior. Anyan J, Verwey M, Amir S 28763478
PSYCHOLOGY
22 Too Depressed to Swim or Too Afraid to Stop? A Reinterpretation of the Forced Swim Test as a Measure of Anxiety-Like Behavior. Anyan J, Amir S 29210364
PSYCHOLOGY
23 mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction Liu D; Stowie A; de Zavalia N; Leise T; Pathak SS; Drewes LR; Davidson AJ; Amir S; Sonenberg N; Cao R; 29555746
CSBN

 

Title:Stress-induced changes in the expression of the clock protein PERIOD1 in the rat limbic forebrain and hypothalamus: role of stress type, time of day, and predictability.
Authors:Al-Safadi S,  Al-Safadi A,  Branchaud M,  Rutherford S,  Dayanandan A,  Robinson B,  Amir S
Link:https://www.ncbi.nlm.nih.gov/pubmed/25338089?dopt=Abstract
Publication:
Keywords:
PMID:25338089 Category:PLoS One Date Added:2019-05-31
Dept Affiliation: CSBN
1 Department of Biology, Concordia University, Montréal, Quebéc, Canada; Department of Psychology, Center for Studies in Behavioral Neurobiology, Concordia University, Montréal, Quebéc, Canada.
2 Department of Psychology, Center for Studies in Behavioral Neurobiology, Concordia University, Montréal, Quebéc, Canada.

Description:

Stress-induced changes in the expression of the clock protein PERIOD1 in the rat limbic forebrain and hypothalamus: role of stress type, time of day, and predictability.

PLoS One. 2014;9(10):e111166

Authors: Al-Safadi S, Al-Safadi A, Branchaud M, Rutherford S, Dayanandan A, Robinson B, Amir S

Abstract

Stressful events can disrupt circadian rhythms in mammals but mechanisms underlying this disruption remain largely unknown. One hypothesis is that stress alters circadian protein expression in the forebrain, leading to functional dysregulation of the brain circadian network and consequent disruption of circadian physiological and behavioral rhythms. Here we characterized the effects of several different stressors on the expression of the core clock protein, PER1 and the activity marker, FOS in select forebrain and hypothalamic nuclei in rats. We found that acute exposure to processive stressors, restraint and forced swim, elevated PER1 and FOS expression in the paraventricular and dorsomedial hypothalamic nuclei and piriform cortex but suppressed PER1 and FOS levels exclusively in the central nucleus of the amygdala (CEAl) and oval nucleus of the bed nucleus of the stria terminalis (BNSTov). Conversely, systemic stressors, interleukin-1ß and 2-Deoxy-D-glucose, increased PER1 and FOS levels in all regions studied, including the CEAl and BNSTov. PER1 levels in the suprachiasmatic nucleus (SCN), the master pacemaker, were unaffected by any of the stress manipulations. The effect of stress on PER1 and FOS was modulated by time of day and, in the case of daily restraint, by predictability. These results demonstrate that the expression of PER1 in the forebrain is modulated by stress, consistent with the hypothesis that PER1 serves as a link between stress and the brain circadian network. Furthermore, the results show that the mechanisms that control PER1 and FOS expression in CEAl and BNSTov are uniquely sensitive to differences in the type of stressor. Finally, the finding that the effect of stress on PER1 parallels its effect on FOS supports the idea that Per1 functions as an immediate-early gene. Our observations point to a novel role for PER1 as a key player in the interface between stress and circadian rhythms.

PMID: 25338089 [PubMed - indexed for MEDLINE]




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