Keyword search (4,163 papers available)

"Amir S" Authored Publications:

Title Authors PubMed ID
1 Disruptive effects of d-amphetamine on conditioned sexual inhibition in the male rat Germé K; Persad D; Petit-Robinson J; Amir S; Pfaus JG; 40232387
PSYCHOLOGY
2 Effects of chronodisruption and alcohol consumption on gene expression in reward-related brain areas in female rats Meyer C; Schoettner K; Amir S; 39624490
PSYCHOLOGY
3 The effects of circadian desynchronization on alcohol consumption and affective behavior during alcohol abstinence in female rats Meyer C; Schoettner K; Amir S; 36620855
CSBN
4 Characterization of Affective Behaviors and Motor Functions in Mice With a Striatal-Specific Deletion of Bmal1 and Per2 Schoettner K; Alonso M; Button M; Goldfarb C; Herrera J; Quteishat N; Meyer C; Bergdahl A; Amir S; 35755440
HKAP
5 Thermoregulatory significance of immobility in the forced swim test Nadeau BG; Marchant EG; Amir S; Mistlberger RE; 35065081
PSYCHOLOGY
6 Bmal1 in the striatum influences alcohol intake in a sexually dimorphic manner de Zavalia N; Schoettner K; Goldsmith JA; Solis P; Ferraro S; Parent G; Amir S; 34702951
PSYCHOLOGY
7 In utero Exposure to Valproic-Acid Alters Circadian Organisation and Clock-Gene Expression: Implications for Autism Spectrum Disorders Ferraro S; de Zavalia N; Belforte N; Amir S; 34650409
CSBN
8 The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4. Pathak SS, Liu D, Li T, de Zavalia N, Zhu L, Li J, Karthikeyan R, Alain T, Liu AC, Storch KF, Kaufman RJ, Jin VX, Amir S, Sonenberg N, Cao R 31522764
CSBN
9 Effects of bilateral anterior agranular insula lesions on food anticipatory activity in rats. Gavrila AM, Hood S, Robinson B, Amir S 28594962
CSBN
10 Circadian Rhythms in Regulation of Brain Processes and Role in Psychiatric Disorders. Pantazopoulos H, Gamble K, Stork O, Amir S 29887881
PSYCHOLOGY
11 Mapping the co-localization of the circadian proteins PER2 and BMAL1 with enkephalin and substance P throughout the rodent forebrain. Frederick A, Goldsmith J, de Zavalia N, Amir S 28423013
BIOLOGY
12 Comprehensive mapping of regional expression of the clock protein PERIOD2 in rat forebrain across the 24-h day. Harbour VL, Weigl Y, Robinson B, Amir S 24124556
PSYCHOLOGY
13 Phase differences in expression of circadian clock genes in the central nucleus of the amygdala, dentate gyrus, and suprachiasmatic nucleus in the rat. Harbour VL, Weigl Y, Robinson B, Amir S 25068868
PSYCHOLOGY
14 Diurnal influences on electrophysiological oscillations and coupling in the dorsal striatum and cerebellar cortex of the anesthetized rat. Frederick A, Bourget-Murray J, Chapman CA, Amir S, Courtemanche R 25309348
BIOLOGY
15 Stress-induced changes in the expression of the clock protein PERIOD1 in the rat limbic forebrain and hypothalamus: role of stress type, time of day, and predictability. Al-Safadi S, Al-Safadi A, Branchaud M, Rutherford S, Dayanandan A, Robinson B, Amir S 25338089
CSBN
16 Light-regulated translational control of circadian behavior by eIF4E phosphorylation. Cao R, Gkogkas CG, de Zavalia N, Blum ID, Yanagiya A, Tsukumo Y, Xu H, Lee C, Storch KF, Liu AC, Amir S, Sonenberg N 25915475
CSBN
17 Glucocorticoids and Stress-Induced Changes in the Expression of PERIOD1 in the Rat Forebrain. Al-Safadi S, Branchaud M, Rutherford S, Amir S 26075608
CSBN
18 Circadian Rhythms and Psychopathology: From Models of Depression to Rhythms in Clock Gene Expression and Back Again. Verwey M, Al-Safadi S, Amir S 26195175
PSYCHOLOGY
19 From genes to chronotypes: the influence of circadian clock genes on our daily patterns of sleep and wakefulness. Verwey M, Amir S 27275497
CSBN
20 Exploring the role of locomotor sensitization in the circadian food entrainment pathway. Opiol H, de Zavalia N, Delorme T, Solis P, Rutherford S, Shalev U, Amir S 28301599
PSYCHOLOGY
21 Individual differences in circadian locomotor parameters correlate with anxiety- and depression-like behavior. Anyan J, Verwey M, Amir S 28763478
PSYCHOLOGY
22 Too Depressed to Swim or Too Afraid to Stop? A Reinterpretation of the Forced Swim Test as a Measure of Anxiety-Like Behavior. Anyan J, Amir S 29210364
PSYCHOLOGY
23 mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction Liu D; Stowie A; de Zavalia N; Leise T; Pathak SS; Drewes LR; Davidson AJ; Amir S; Sonenberg N; Cao R; 29555746
CSBN

 

Title:Glucocorticoids and Stress-Induced Changes in the Expression of PERIOD1 in the Rat Forebrain.
Authors:Al-Safadi S,  Branchaud M,  Rutherford S,  Amir S
Link:https://www.ncbi.nlm.nih.gov/pubmed/26075608?dopt=Abstract
Publication:
Keywords:
PMID:26075608 Category:PLoS One Date Added:2019-05-31
Dept Affiliation: CSBN
1 Department of Biology, Concordia University, SP-375.07, 7141 Sherbrooke Street West, Montréal, Quebéc, H4B 1R6, Canada; Department of Psychology, Center for Studies in Behavioral Neurobiology, Concordia University, SP-244, 7141 Sherbrooke Street West, Montréal, Quebéc, H4B 1R6, Canada.
2 Department of Psychology, Center for Studies in Behavioral Neurobiology, Concordia University, SP-244, 7141 Sherbrooke Street West, Montréal, Quebéc, H4B 1R6, Canada.

Description:

Glucocorticoids and Stress-Induced Changes in the Expression of PERIOD1 in the Rat Forebrain.

PLoS One. 2015;10(6):e0130085

Authors: Al-Safadi S, Branchaud M, Rutherford S, Amir S

Abstract

The secretion of glucocorticoids in mammals is under circadian control, but glucocorticoids themselves are also implicated in modulating circadian clock gene expression. We have shown that the expression of the circadian clock protein PER1 in the forebrain is modulated by stress, and that this effect is associated with changes in plasma corticosterone levels, suggesting a possible role for glucocorticoids in the mediation of stress-induced changes in the expression of PER1 in the brain. To study this, we assessed the effects of adrenalectomy and of pretreatment with the glucocorticoid receptor antagonist, mifepristone, on the expression of PER1 in select limbic and hypothalamic regions following acute exposure to a neurogenic stressor, restraint, or a systemic stressor, 2-Deoxy-D-glucose (2DG) in rats. Acute restraint suppressed PER1 expression in the oval nucleus of the bed nucleus of the stria terminalis (BNSTov) and the central nucleus of the amygdala (CEAl), whereas 2DG increased PER1 in both regions. Both stressors increased PER1 expression in the paraventricular (PVN) and dorsomedial (DMH) nuclei of the hypothalamus, and the piriform cortex (Pi). Adrenalectomy and pretreatment with mifepristone reversed the effects of both stressors on PER1 expression in the BNSTov and CEAl, and blocked their effects in the DMH. In contrast, both treatments enhanced the effects of restraint and 2DG on PER1 levels in the PVN. Stress-induced PER1 expression in the Pi was unaffected by either treatment. PER1 expression in the suprachiasmatic nucleus, the master circadian clock, was not altered by either exposure to stress or by the glucocorticoid manipulations. Together, the results demonstrate a key role for glucocorticoid signaling in stress-induced changes in PER1 expression in the brain.

PMID: 26075608 [PubMed - indexed for MEDLINE]




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