BookR: School of Health Core Facilities Booking
PubMed Publications| Keyword search (4,163 papers available) |  |
"genetics" Keyword-tagged Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Smart Optogenetics for Real-Time Automated Control of Cardiac Electrical Activity | Deng S; Harlaar N; Zhang J; Dekker SO; Kudryashova NN; Zhou H; Bart CI; Jin T; Derevyanko G; van Driel W; Panfilov AV; Poelma RH; de Vries AAF; Zhang G; De Coster T; Pijnappels DA; | 41684280 CHEMBIOCHEM |
| 2 | Genetic dissection of stool frequency implicates vitamin B1 metabolism and other actionable pathways in the modulation of gut motility | Díaz-Muñoz C; Bozzarelli I; Lopera-Maya EA; Belbasis L; Lo Faro V; Camargo Tavares L; Heredia-Fernández F; Di Lorenzo B; Sinha T; Esteban Blanco C; Favé MJ; Awadalla P; Walters RG; Bonfiglio F; Zhernakova A; Sanna S; D' Amato M; | 41558814 BIOLOGY |
| 3 | Cross-species evaluation of TANGO2 homologs, including HRG-9 and HRG-10 in em Caenorhabditis elegans, /em challenges a proposed role in heme trafficking | Sandkuhler SE; Youngs KS; Gottipalli O; Owlett LD; Bandora MB; Naaz A; Kim E; Wang L; Wojtovich A; Gupta V; Sacher M; Mackenzie SJ; | 41504601 BIOLOGY |
| 4 | Activation of infralimbic cortex neurons projecting to the nucleus accumbens shell suppresses discriminative stimulus-triggered relapse to cocaine seeking in rats | Algallal HE; Laplante I; Casale D; Najafipashaki S; Pomerleau A; Paquette T; Samaha AN; | 41372546 PSYCHOLOGY |
| 5 | Disentangling prediction error and value in a formal test of dopamine s role in reinforcement learning | Usypchuk AA; Maes EJP; Lozzi M; Avramidis DK; Schoenbaum G; Esber GR; Gardner MPH; Iordanova MD; | 40738112 CSBN |
| 6 | Single-cell imaging of protein dynamics of paralogs reveals sources of gene retention | Dandage R; Papkov M; Greco BM; Pereira V; Fishman D; Friesen H; Wang K; Styles EB; Kraus O; Grys B; Zapata G; Lefebvre F; Bourque G; Boone C; Andrews BJ; Parts L; Kuzmin E; | 40585364 BIOLOGY |
| 7 | SEC24C deficiency causes trafficking and glycosylation abnormalities in an epileptic encephalopathy with cataracts and dyserythropoeisis | Bögershausen N; Cavdarli B; Nagai T; Milev MP; Wolff A; Mehranfar M; Schmidt J; Choudhary D; Gutiérrez-Gutiérrez Ó; Cyganek L; Saint-Dic D; Zibat A; Köhrer K; Wollenweber TE; Wieczorek D; Altmüller J; Borodina T; Kaçar D; Haliloglu G; Li Y; Thiel C; Sacher M; Knapik EW; Yigit G; Wollnik B; | 40131364 BIOLOGY |
| 8 | Shared Dispersal Patterns but Contrasting Levels of Gene Flow in Two Anadromous Salmonids Along a Broad Subarctic Coastal Gradient | Bouchard R; Babin C; Normandeau E; Xuereb A; Boulanger F; Coxon A; Diamond S; Fireman R; Lameboy J; Louttit N; Natawapineskum G; Okimaw D; Torio D; Varty S; Moore JS; Fraser D; Bernatchez L; | 40108992 CONCORDIA |
| 9 | Temporal Variability in Effective Size ( [Formula] ) Identifies Potential Sources of Discrepancies Between Mark Recapture and Close Kin Mark Recapture Estimates of Population Abundance | Ruzzante DE; McCracken GR; Fraser DJ; MacMillan J; Buhariwalla C; Flemming JM; | 39582254 BIOLOGY |
| 10 | Defects in meiosis I contribute to the genesis of androgenetic hydatidiform moles | Rezaei M; Liang M; Yalcin Z; Martin JH; Kazemi P; Bareke E; Ge ZJ; Fardaei M; Benadiva C; Hemida R; Hassan A; Maher GJ; Abdalla E; Buckett W; Bolze PA; Sandhu I; Duman O; Agrawal S; Qian J; Vallian Broojeni J; Bhati L; Miron P; Allias F; Selim A; Fisher RA; Seckl MJ; Sauthier P; Touitou I; Tan SL; Majewski J; Taketo T; Slim R; | 39545410 BIOLOGY |
| 11 | What can optimized cost distances based on genetic distances offer? A simulation study on the use and misuse of ResistanceGA | Daniel A; Savary P; Foltête JC; Vuidel G; Faivre B; Garnier S; Khimoun A; | 39417711 BIOLOGY |
| 12 | Global assessment of effective population sizes: Consistent taxonomic differences in meeting the 50/500 rule | Clarke SH; Lawrence ER; Matte JM; Gallagher BK; Salisbury SJ; Michaelides SN; Koumrouyan R; Ruzzante DE; Grant JWA; Fraser DJ; | 38613250 BIOLOGY |
| 13 | Macrogenetics reveals multifaceted influences of environmental variation on vertebrate population genetic diversity across the Americas | Lawrence ER; Pedersen EJ; Fraser DJ; | 37365672 BIOLOGY |
| 14 | Demographic resilience of brook trout populations subjected to experimental size-selective harvesting | Clarke SH; McCracken GR; Humphries S; Ruzzante DE; Grant JWA; Fraser DJ; | 36426123 BIOLOGY |
| 15 | Potential epigenetic mechanisms in psychotherapy: a pilot study on DNA methylation and mentalization change in borderline personality disorder | Quevedo Y; Booij L; Herrera L; Hernández C; Jiménez JP; | 36171872 PSYCHOLOGY |
| 16 | DNA methylation as a mediator in the association between prenatal maternal stress and child mental health outcomes: Current state of knowledge | Azar N; Booij L; | 36113690 PSYCHOLOGY |
| 17 | Population demography maintains biogeographic boundaries | Schmidt C; Muñoz G; Lancaster LT; Lessard JP; Marske KA; Marshall KE; Garroway CJ; | 35753949 BIOLOGY |
| 18 | DNA methylation in people with Anorexia Nervosa: Epigenome-wide patterns in actively ill, long-term remitted, and healthy-eater women | Steiger H; Booij L; Thaler L; St-Hilaire A; Israël M; Casey KF; Oliverio S; Crescenzi O; Lee V; Turecki G; Joober R; Szyf M; Breton É; | 35703085 PSYCHOLOGY |
| 19 | Dissecting cell fate dynamics in pediatric glioblastoma through the lens of complex systems and cellular cybernetics | Abicumaran Uthamacumaran | 35678918 PHYSICS |
| 20 | Immunoinflammatory processes: Overlapping mechanisms between obesity and eating disorders? | Breton E; Fotso Soh J; Booij L; | 35594735 PSYCHOLOGY |
| 21 | Corticostriatal suppression of appetitive Pavlovian conditioned responding | Villaruel FR; Martins M; Chaudhri N; | 34880119 PSYCHOLOGY |
| 22 | The trade-off between pulse duration and power in optical excitation of midbrain dopamine neurons approximates Bloch's law | Pallikaras V; Carter F; Velazquez-Martinez DN; Arvanitogiannis A; Shizgal P; | 34864162 PSYCHOLOGY |
| 23 | Location and Species Matters: Variable Influence of the Environment on the Gene Flow of Imperiled, Native and Invasive Cottontails | McGreevy TJ; Michaelides S; Djan M; Sullivan M; Beltrán DM; Buffum B; Husband T; | 34659333 BIOLOGY |
| 24 | Seeing is believing: tools to study the role of Rho GTPases during cytokinesis | Koh SP; Pham NP; Piekny A; | 34405757 BIOLOGY |
| 25 | All-optical approaches to studying psychiatric disease | Lafferty CK; Christinck TD; Britt JP; | 34314828 CSBN |
| 26 | Methodological and clinical challenges associated with biomarkers for psychiatric disease: A scoping review. | Kirkpatrick RH; Munoz DP; Khalid-Khan S; Booij L; | 33221025 PSYCHOLOGY |
| 27 | The Relationship Between Cognitive Status and Known Single Nucleotide Polymorphisms in Age-Related Macular Degeneration. | Murphy C; Johnson AP; Koenekoop RK; Seiple W; Overbury O; | 33178008 PSYCHOLOGY |
| 28 | A novel homozygous variant in TRAPPC2L results in a neurodevelopmental disorder and disrupts TRAPP complex function. | Al-Deri N, Okur V, Ahimaz P, Milev M, Valivullah Z, Hagen J, Sheng Y, Chung W, Sacher M, Ganapathi M | 32843486 BIOLOGY |
| 29 | DNA methylation differences in stress-related genes, functional connectivity and gray matter volume in depressed and healthy adolescents. | Chiarella J, Schumann L, Pomares FB, Frodl T, Tozzi L, Nemoda Z, Yu P, Szyf M, Khalid-Khan S, Booij L | 32479312 PSYCHOLOGY |
| 30 | Eating Disorders, Heredity and Environmental Activation: Getting Epigenetic Concepts into Practice. | Steiger H, Booij L | 32375223 PSYCHOLOGY |
| 31 | Off-Target Influences of Arch-Mediated Axon Terminal Inhibition on Network Activity and Behavior. | Lafferty CK, Britt JP | 32269514 CSBN |
| 32 | Nucleus Accumbens Cell Type- and Input-Specific Suppression of Unproductive Reward Seeking. | Lafferty CK, Yang AK, Mendoza JA, Britt JP | 32187545 CSBN |
| 33 | The Neuroscience of Sadness: A Multidisciplinary Synthesis and Collaborative Review for the Human Affectome Project. | Arias JA, Williams C, Raghvani R, Aghajani M, Baez S, Belzung C, Booij L, Busatto G, Chiarella J, Fu CH, Ibanez A, Liddell BJ, Lowe L, Penninx BWJH, Rosa P, Kemp AH | 32001274 PSYCHOLOGY |
| 34 | Methylation of the OXTR gene in women with anorexia nervosa: Relationship to social behavior. | Thaler L, Brassard S, Booij L, Kahan E, McGregor K, Labbe A, Israel M, Steiger H | 31823473 PSYCHOLOGY |
| 35 | Deficiencies in vesicular transport mediated by TRAPPC4 are associated with severe syndromic intellectual disability. | Van Bergen NJ, Guo Y, Al-Deri N, Lipatova Z, Stanga D, Zhao S, Murtazina R, Gyurkovska V, Pehlivan D, Mitani T, Gezdirici A, Antony J, Collins F, Willis MJH, Coban Akdemir ZH, Liu P, Punetha J, Hunter JV, Jhangiani SN, Fatih JM, Rosenfeld JA, Posey JE, Gibbs RA, Karaca E, Massey S, Ranasinghe TG, Sleiman P, Troedson C, Lupski JR, Sacher M, Segev N, Hakonarson H, Christodoulou J | 31794024 BIOLOGY |
| 36 | Hippocampal Input to the Nucleus Accumbens Shell Enhances Food Palatability. | Yang AK, Mendoza JA, Lafferty CK, Lacroix F, Britt JP | 31699294 CSBN |
| 37 | Cue-Evoked Dopamine Neuron Activity Helps Maintain but Does Not Encode Expected Value. | Mendoza JA, Lafferty CK, Yang AK, Britt JP | 31693885 CSBN |
| 38 | Birth weight discordance, DNA methylation, and cortical morphology of adolescent monozygotic twins. | Casey KF, Levesque ML, Szyf M, Ismaylova E, Verner MP, Suderman M, Vitaro F, Brendgen M, Dionne G, Boivin M, Tremblay RE, Booij L | 28032437 PSYCHOLOGY |
| 39 | A critical assessment of estimating census population size from genetic population size (or vice versa) in three fishes. | Yates MC, Bernos TA, Fraser DJ | 29151884 BIOLOGY |
| 40 | Genetic diversity of small populations: Not always "doom and gloom"? | Fraser DJ | 29243868 BIOLOGY |
| Title: | DNA methylation as a mediator in the association between prenatal maternal stress and child mental health outcomes: Current state of knowledge | ||||
| Authors: | Azar N, Booij L | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/36113690/ | ||||
| DOI: | 10.1016/j.jad.2022.09.008 | ||||
| Publication: | Journal of affective disorders | ||||
| Keywords: | DNA methylation; Epigenetics; Externalizing problems; Internalizing problems; Mental health; Prenatal maternal stress; | ||||
| PMID: | 36113690 | Category: | Date Added: | 2022-09-17 | |
| Dept Affiliation: |
PSYCHOLOGY
1 Department of Psychology, Concordia University, 7141 Sherbrooke Street West, Montreal, Quebec H4B 1R6, Canada; Sainte-Justine University Hospital Research Center, 3175 chemin de la Côte-Sainte-Catherine, Montreal, Quebec H3T 1C5, Canada. 2 Department of Psychology, Concordia University, 7141 Sherbrooke Street West, Montreal, Quebec H4B 1R6, Canada; Sainte-Justine University Hospital Research Center, 3175 chemin de la Côte-Sainte-Catherine, Montreal, Quebec H3T 1C5, Canada; Department of Psychiatry and Addictology, Faculty of Medicine, Pavillon Roger-Gaudry, Université de Montréal, P.O. Box 6128, succursale Centre-ville, Montréal, Québec H3C 3J7, Canada. Electronic address: linda.booij@concordia.ca. |
||||
Description: |
Background: Prenatal maternal stress is increasingly recognized as a risk factor for offspring mental health challenges. DNA methylation may be a mechanism, but few studies directly tested mediation. These few integrative studies are reviewed along with studies from three research areas: prenatal maternal stress and child mental health, prenatal maternal stress and child DNA methylation, and child mental health and DNA methylation. Methods: We conducted a narrative review of articles in each research area and the few published integrative studies to evaluate the state of knowledge. Results: Prenatal maternal stress was related to greater offspring internalizing and externalizing symptoms and to greater offspring peripheral DNA methylation of the NR3C1 gene. Youth mental health problems were also related to NR3C1 hypermethylation while epigenome-wide studies identified genes involved in nervous system development. Integrative studies focused on infant outcomes and did not detect significant mediation by DNA methylation though methodological considerations may partially explain these null results. Limitations: Operationalization of prenatal maternal stress and child mental health varied greatly. The few published integrative studies did not report conclusive evidence of mediation by DNA methylation. Conclusions: DNA methylation likely mediates the association between prenatal maternal stress and child mental health. This conclusion still needs to be tested in a larger number of integrative studies. Key empirical and statistical considerations for future research are discussed. Understanding the consequences of prenatal maternal stress and its pathways of influence will help prevention and intervention efforts and ultimately promote well-being for both mothers and children. |
