| Keyword search (4,163 papers available) | ![]() |
"Trial" Keyword-tagged Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Resistance training and subcortical vascular cognitive impairment: A 12-month randomized trial | Liu-Ambrose T; Falck RS; Dao E; Crockett RA; Barha CK; Silva NCBS; Alkeridy WA; Best JR; Hsiung GR; Field TS; Madden KM; Davis JC; Ten Brinke LF; Tam RC; | 41795685 HKAP |
| 2 | Toward a Sustainable Future: A Holistic Environmental, Social, and Economic Assessment of Industrial Recycling for All-Solid-State Batteries with Oxide-Based Electrolytes | Wang Z; Tian X; Zhao S; Zhang P; An C; | 41073076 ENCS |
| 3 | Post-subsidy Era: Potential for Carbon Pricing in Industrial Fisheries among Global Major Fishing Countries | Peng H; Hao J; Lyu L; Wan S; An C; | 40737555 ENCS |
| 4 | Use of lecanemab and donanemab in the Canadian healthcare system: Evidence, challenges, and areas for future research | Smith EE; Phillips NA; Feldman HH; Borrie M; Ganesh A; Henri-Bhargava A; Desmarais P; Frank A; Badhwar A; Barlow L; Bartha R; Best S; Bethell J; Bhangu J; Black SE; Bocti C; Bronskill SE; Burhan AM; Calon F; Camicioli R; Campbell B; Collins DL; Dadar M; DeMarco ML; Ducharme S; Duchesne S; Einstein G; Fisk JD; Gawryluk JR; Grossman L; Ismail Z; Itzhak I; Joshi M; Harrison A; Kroger E; Kumar S; Laforce R; Lanctot KL; Lau M; Lee L; Masellis M; Massoud F; Mitchell SB; Montero-Odasso M; Myers Barnett K; Nygaard HB; Pasternak SH; Peters J; Rajah MN; Robillard JM; Rockwood K; Rosa-Neto P; Seitz DP; Soucy JP; Trenaman SC; Wellington CL; Zadem A; Chertkow H; | 39893139 CONCORDIA |
| 5 | The hockey fans in training intervention for men with overweight or obesity: a pragmatic cluster randomised trial | Petrella RJ; Gill DP; Boa Sorte Silva NC; Riggin B; Blunt WM; Kfrerer M; Majoni M; Marsh J; Irwin JD; Stranges S; Zwarenstein M; Zou G; | 39568632 HKAP |
| 6 | A protocol for trustworthy EEG decoding with neural networks | Borra D; Magosso E; Ravanelli M; | 39549492 ENCS |
| 7 | AAT4IRS: automated acceptance testing for industrial robotic systems | Dos Santos MG; Hallé S; Petrillo F; Guéhéneuc YG; | 39420929 ENCS |
| 8 | Investigating the kinetics of marine and terrestrial organic carbon incorporation and degradation in coastal bulk sediment and water settings through isotopic lenses | Mirzaei Y; Gélinas Y; | 39117203 CHEMBIOCHEM |
| 9 | A randomized controlled trial of an acceptance-based, insight-inducing medication adherence therapy (AIM-AT) for adults with early-stage psychosis | Chien WT; Chong YY; Bressington D; McMaster CW; | 38908265 CONCORDIA |
| 10 | How to present work productivity loss results from clinical trials for patients and caregivers? A mixed methods approach | L' Heureux J; McTaggart-Cowan H; Johns G; Chen L; Steiner T; Tocher P; Sun H; Zhang W; | 37276772 JMSB |
| 11 | Prospects of Novel and Repurposed Immunomodulatory Drugs against Acute Respiratory Distress Syndrome (ARDS) Associated with COVID-19 Disease | Nayak SS; Naidu A; Sudhakaran SL; Vino S; Selvaraj G; | 37109050 CHEMBIOCHEM |
| 12 | A multi-center, randomized, 12-month, parallel-group, feasibility study to assess the acceptability and preliminary impact of family navigation plus usual care versus usual care on attrition in managing pediatric obesity: a study protocol | Ball GDC; O' Neill MG; Noor R; Alberga A; Azar R; Buchholz A; Enright M; Geller J; Ho J; Holt NL; Lebel T; Rosychuk RJ; Tarride JE; Zenlea I; | 36691103 HKAP |
| 13 | The effects of walking in nature on negative and positive affect in adult psychiatric outpatients with major depressive disorder: A randomized-controlled study | Watkins-Martin K; Bolani D; Richard-Devantoy S; Pennestri MH; Malboeuf-Hurtubise C; Philippe F; Guindon J; Gouin JP; Ouellet-Morin I; Geoffroy MC; | 36058362 PSYCHOLOGY |
| 14 | Neural evidence for age-related deficits in the representation of state spaces | Ruel A; Bolenz F; Li SC; Fischer A; Eppinger B; | 35510942 PERFORM |
| 15 | Recent developments in photocatalysis of industrial effluents ։ A review and example of phenolic compounds degradation | Motamedi M; Yerushalmi L; Haghighat F; Chen Z; | 35074327 ENCS |
| 16 | Protocol for a partially nested randomised controlled trial to evaluate the effectiveness of the scleroderma patient-centered intervention network COVID-19 home-isolation activities together (SPIN-CHAT) program to reduce anxiety among at-risk scleroderma patients. | Thombs BD, Kwakkenbos L, Carrier ME, Bourgeault A, Tao L, Harb S, Gagarine M, Rice D, Bustamante L, Ellis K, Duchek D, Wu Y, Bhandari PM, Neupane D, Carboni-Jiménez A, Henry RS, Krishnan A, Sun Y, Levis B, He C, Turner KA, Benedetti A, Culos-Reed N, El-Baalbaki G, Hebblethwaite S, Bartlett SJ, Dyas L, Patten S, Varga J, Scleroderma Patient-centered Intervention Network (SPIN) COVID-19 Patient Advisory Team, SPIN Investigators | 32521358 PSYCHOLOGY |
| 17 | Protocol for a partially nested randomised controlled trial to evaluate the effectiveness of the scleroderma patient-centered intervention network COVID-19 home-isolation activities together (SPIN-CHAT) program to reduce anxiety among at-risk scleroderma patients. | Fortuné C, Gietzen A, Guillot G, Lewis N, Nielsen K, Richard M, Sauvé M, Welling J, SPIN Investigators, Baron M, Furst DE, Gottesman K, Malcarne V, Mayes MD, Mouthon L, Nielson WR, Riggs R, Wigley F, Assassi S, Boutron I, Ells C, van den Ende C, Fligelstone K, Frech T, Godard D, Harel D, Hinchcliff M, Hudson M, Johnson SR, Larche M, Leite C, Nguyen C, Pope J, Portales A, Rannou F, Reyna TSR, Schouffoer AA, Suarez-Almazor ME, Agard C, Albert A, André M, Arsenault G, Benzidia I, Bernstein EJ, Berthier S, Biss | 32419703 PSYCHOLOGY |
| 18 | An international, Delphi consensus study to identify priorities for methodological research in behavioral trials in health research. | Byrne M, McSharry J, Meade O, Lavoie KL, Bacon SL | 32293510 HKAP |
| 19 | Group sample sizes in nonregulated health care intervention trials described as randomized controlled trials were overly similar | Thombs BD; Levis AW; Azar M; Saadat N; Riehm KE; Sanchez TA; Chiovitti MJ; Rice DB; Levis B; Fedoruk C; Lyubenova A; Malo Vázquez de Lara AL; Kloda LA; Benedetti A; Shrier I; Platt RW; Kimmelman J; | 31866472 LIBRARY |
| 20 | Reproducibility of EEG-MEG fusion source analysis of interictal spikes: Relevance in presurgical evaluation of epilepsy. | Chowdhury RA, Pellegrino G, Aydin Ü, Lina JM, Dubeau F, Kobayashi E, Grova C | 29164737 PERFORM |
| Title: | Resistance training and subcortical vascular cognitive impairment: A 12-month randomized trial | ||||
| Authors: | Liu-Ambrose T, Falck RS, Dao E, Crockett RA, Barha CK, Silva NCBS, Alkeridy WA, Best JR, Hsiung GR, Field TS, Madden KM, Davis JC, Ten Brinke LF, Tam RC | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/41795685/ | ||||
| DOI: | 10.1002/alz.71245 | ||||
| Publication: | Alzheimer s & dementia : the journal of the Alzheimer s Association | ||||
| Keywords: | mild cognitive impairment; progressive resistance training; randomized controlled trial; vascular cognitive impairment; | ||||
| PMID: | 41795685 | Category: | Date Added: | 2026-03-08 | |
| Dept Affiliation: |
HKAP
1 Department of Physical Therapy, University of British Columbia, Vancouver, British Columbia, Canada. 2 Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada. 3 Centre for Aging SMART at Vancouver Coastal Health, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada. 4 School of Biomedical Engineering, University of British Columbia, Vancouver, British Columbia, Canada. 5 Department of Radiology, University of British Columbia, Vancouver, British Columbia, Canada. 6 International Collaboration on Repair Discoveries, Vancouver, British Columbia, Canada. 7 Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. 8 Barha Brain Health Laboratory, Faculty of Kinesiology, University of Calgary,Calgary, Alberta, Canada. 9 Department of Health, Kinesiology, and Applied Physiology, Concordia University, Montréal, Québec, Canada. 10 Division of Neurology, University of British Columbia, Vancouver, British Columbia, Canada. 11 Department of Medicine, King Saud University, College of Medicine, Riyadh, Saudi Arabia. 12 Department of Medicine, Division of Geriatric Medicine, University of British Columbia, Vancouver, British Columbia, Canada. 13 Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada. 14 Vancouver Stroke Program, Vancouver, British Columbia, Canada. 15 Faculty of Management, University of British Columbia-Okanagan, British Columbia, Kelowna, Canada. |
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Description: |
Introduction: It is unknown whether progressive resistance training (PRT) improves cognitive function in adults with cerebral small vessel disease and mild cognitive impairment (i.e., subcortical vascular cognitive impairment [SVCI]). Methods: We conducted a 12-month randomized trial comparing PRT versus balance and tone exercises (BAT) on the Alzheimer's Disease Assessment Scale Cognitive Plus (ADAS-Cog-Plus). Results: Ninety-one participants were randomized (PRT = 45; BAT = 46); 76 completed the trial. Adherence was not different between groups (p = 0.18). At 12 months, PRT significantly improved ADAS-Cog-Plus scores (estimated mean difference: -0.18; 95% confidence interval [CI: -0.35, -0.01]; p = 0.04). Planned contrasts stratified by sex showed a significant PRT effect on ADAS-Cog-Plus scores for females (mean difference: -0.27; 95% CI: [-0.49, -0.05]; p = 0.02), but not for males. PRT also significantly reduced C-reactive protein (estimated mean difference: -2.93; 95% CI: [-5.36, -0.49]; p = 0.02). No significant differences were observed for other secondary outcomes. Discussion: PRT may have a small beneficial effect on cognitive function in SVCI. Clinical trial registration: This trial was registered with ClinicalTrials.gov (NCT02669394). |



