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PubMed Publications| Keyword search (4,163 papers available) |  |
"Trial" Keyword-tagged Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Resistance training and subcortical vascular cognitive impairment: A 12-month randomized trial | Liu-Ambrose T; Falck RS; Dao E; Crockett RA; Barha CK; Silva NCBS; Alkeridy WA; Best JR; Hsiung GR; Field TS; Madden KM; Davis JC; Ten Brinke LF; Tam RC; | 41795685 HKAP |
| 2 | Toward a Sustainable Future: A Holistic Environmental, Social, and Economic Assessment of Industrial Recycling for All-Solid-State Batteries with Oxide-Based Electrolytes | Wang Z; Tian X; Zhao S; Zhang P; An C; | 41073076 ENCS |
| 3 | Post-subsidy Era: Potential for Carbon Pricing in Industrial Fisheries among Global Major Fishing Countries | Peng H; Hao J; Lyu L; Wan S; An C; | 40737555 ENCS |
| 4 | Use of lecanemab and donanemab in the Canadian healthcare system: Evidence, challenges, and areas for future research | Smith EE; Phillips NA; Feldman HH; Borrie M; Ganesh A; Henri-Bhargava A; Desmarais P; Frank A; Badhwar A; Barlow L; Bartha R; Best S; Bethell J; Bhangu J; Black SE; Bocti C; Bronskill SE; Burhan AM; Calon F; Camicioli R; Campbell B; Collins DL; Dadar M; DeMarco ML; Ducharme S; Duchesne S; Einstein G; Fisk JD; Gawryluk JR; Grossman L; Ismail Z; Itzhak I; Joshi M; Harrison A; Kroger E; Kumar S; Laforce R; Lanctot KL; Lau M; Lee L; Masellis M; Massoud F; Mitchell SB; Montero-Odasso M; Myers Barnett K; Nygaard HB; Pasternak SH; Peters J; Rajah MN; Robillard JM; Rockwood K; Rosa-Neto P; Seitz DP; Soucy JP; Trenaman SC; Wellington CL; Zadem A; Chertkow H; | 39893139 CONCORDIA |
| 5 | The hockey fans in training intervention for men with overweight or obesity: a pragmatic cluster randomised trial | Petrella RJ; Gill DP; Boa Sorte Silva NC; Riggin B; Blunt WM; Kfrerer M; Majoni M; Marsh J; Irwin JD; Stranges S; Zwarenstein M; Zou G; | 39568632 HKAP |
| 6 | A protocol for trustworthy EEG decoding with neural networks | Borra D; Magosso E; Ravanelli M; | 39549492 ENCS |
| 7 | AAT4IRS: automated acceptance testing for industrial robotic systems | Dos Santos MG; Hallé S; Petrillo F; Guéhéneuc YG; | 39420929 ENCS |
| 8 | Investigating the kinetics of marine and terrestrial organic carbon incorporation and degradation in coastal bulk sediment and water settings through isotopic lenses | Mirzaei Y; Gélinas Y; | 39117203 CHEMBIOCHEM |
| 9 | A randomized controlled trial of an acceptance-based, insight-inducing medication adherence therapy (AIM-AT) for adults with early-stage psychosis | Chien WT; Chong YY; Bressington D; McMaster CW; | 38908265 CONCORDIA |
| 10 | How to present work productivity loss results from clinical trials for patients and caregivers? A mixed methods approach | L' Heureux J; McTaggart-Cowan H; Johns G; Chen L; Steiner T; Tocher P; Sun H; Zhang W; | 37276772 JMSB |
| 11 | Prospects of Novel and Repurposed Immunomodulatory Drugs against Acute Respiratory Distress Syndrome (ARDS) Associated with COVID-19 Disease | Nayak SS; Naidu A; Sudhakaran SL; Vino S; Selvaraj G; | 37109050 CHEMBIOCHEM |
| 12 | A multi-center, randomized, 12-month, parallel-group, feasibility study to assess the acceptability and preliminary impact of family navigation plus usual care versus usual care on attrition in managing pediatric obesity: a study protocol | Ball GDC; O' Neill MG; Noor R; Alberga A; Azar R; Buchholz A; Enright M; Geller J; Ho J; Holt NL; Lebel T; Rosychuk RJ; Tarride JE; Zenlea I; | 36691103 HKAP |
| 13 | The effects of walking in nature on negative and positive affect in adult psychiatric outpatients with major depressive disorder: A randomized-controlled study | Watkins-Martin K; Bolani D; Richard-Devantoy S; Pennestri MH; Malboeuf-Hurtubise C; Philippe F; Guindon J; Gouin JP; Ouellet-Morin I; Geoffroy MC; | 36058362 PSYCHOLOGY |
| 14 | Neural evidence for age-related deficits in the representation of state spaces | Ruel A; Bolenz F; Li SC; Fischer A; Eppinger B; | 35510942 PERFORM |
| 15 | Recent developments in photocatalysis of industrial effluents ։ A review and example of phenolic compounds degradation | Motamedi M; Yerushalmi L; Haghighat F; Chen Z; | 35074327 ENCS |
| 16 | Protocol for a partially nested randomised controlled trial to evaluate the effectiveness of the scleroderma patient-centered intervention network COVID-19 home-isolation activities together (SPIN-CHAT) program to reduce anxiety among at-risk scleroderma patients. | Thombs BD, Kwakkenbos L, Carrier ME, Bourgeault A, Tao L, Harb S, Gagarine M, Rice D, Bustamante L, Ellis K, Duchek D, Wu Y, Bhandari PM, Neupane D, Carboni-Jiménez A, Henry RS, Krishnan A, Sun Y, Levis B, He C, Turner KA, Benedetti A, Culos-Reed N, El-Baalbaki G, Hebblethwaite S, Bartlett SJ, Dyas L, Patten S, Varga J, Scleroderma Patient-centered Intervention Network (SPIN) COVID-19 Patient Advisory Team, SPIN Investigators | 32521358 PSYCHOLOGY |
| 17 | Protocol for a partially nested randomised controlled trial to evaluate the effectiveness of the scleroderma patient-centered intervention network COVID-19 home-isolation activities together (SPIN-CHAT) program to reduce anxiety among at-risk scleroderma patients. | Fortuné C, Gietzen A, Guillot G, Lewis N, Nielsen K, Richard M, Sauvé M, Welling J, SPIN Investigators, Baron M, Furst DE, Gottesman K, Malcarne V, Mayes MD, Mouthon L, Nielson WR, Riggs R, Wigley F, Assassi S, Boutron I, Ells C, van den Ende C, Fligelstone K, Frech T, Godard D, Harel D, Hinchcliff M, Hudson M, Johnson SR, Larche M, Leite C, Nguyen C, Pope J, Portales A, Rannou F, Reyna TSR, Schouffoer AA, Suarez-Almazor ME, Agard C, Albert A, André M, Arsenault G, Benzidia I, Bernstein EJ, Berthier S, Biss | 32419703 PSYCHOLOGY |
| 18 | An international, Delphi consensus study to identify priorities for methodological research in behavioral trials in health research. | Byrne M, McSharry J, Meade O, Lavoie KL, Bacon SL | 32293510 HKAP |
| 19 | Group sample sizes in nonregulated health care intervention trials described as randomized controlled trials were overly similar | Thombs BD; Levis AW; Azar M; Saadat N; Riehm KE; Sanchez TA; Chiovitti MJ; Rice DB; Levis B; Fedoruk C; Lyubenova A; Malo Vázquez de Lara AL; Kloda LA; Benedetti A; Shrier I; Platt RW; Kimmelman J; | 31866472 LIBRARY |
| 20 | Reproducibility of EEG-MEG fusion source analysis of interictal spikes: Relevance in presurgical evaluation of epilepsy. | Chowdhury RA, Pellegrino G, Aydin Ü, Lina JM, Dubeau F, Kobayashi E, Grova C | 29164737 PERFORM |
| Title: | Neural evidence for age-related deficits in the representation of state spaces | ||||
| Authors: | Ruel A, Bolenz F, Li SC, Fischer A, Eppinger B | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/35510942/ | ||||
| DOI: | 10.1093/cercor/bhac171 | ||||
| Publication: | Cerebral cortex (New York, N.Y. : 1991) | ||||
| Keywords: | ERP; decision-making; model-based; model-free; reinforcement-learning; single-trial EEG; task demands; | ||||
| PMID: | 35510942 | Category: | Date Added: | 2022-05-05 | |
| Dept Affiliation: |
PERFORM
1 Department of Psychology, Concordia University, 7141 Sherbrooke Street W. Montreal, Quebec H4B 1R6, Canada. 2 Chair of Lifespan Developmental Neuroscience, Faculty of Psychology, Technische Universität Dresden, Bürogebäude, Zi. 244 Strehlener Straße 22/24, Dresden 01069, Germany. 3 Center for Adaptive Rationality, Max Planck Institute for Human Development, Lentzeallee 94, Berlin 14195, Germany. 4 Cluster of Excellence "Science of Intelligence", Technische Universität Berlin, Straße des 17. Juni 135, Berlin 10623, Germany. 5 Cluster of Excellence "Centre for Tactile Internet with Human-in-the-Loop", Technische Universität Dresden, Bürogebäude, Zi. 244 Strehlener Straße 22/24, Dresden 01069, Germany. 6 Department of Education and Psychology, Freie Universität Berlin, Habelschwerdter Allee 45, Berlin 14195, Germany. 7 PERFORM Center, Concordia University, 7200 Sherbrooke St. W. Montreal, Quebec H4B 1R6, Canada. |
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Description: |
Under high cognitive demands, older adults tend to resort to simpler, habitual, or model-free decision strategies. This age-related shift in decision behavior has been attributed to deficits in the representation of the cognitive maps, or state spaces, necessary for more complex model-based decision-making. Yet, the neural mechanisms behind this shift remain unclear. In this study, we used a modified 2-stage Markov task in combination with computational modeling and single-trial EEG analyses to establish neural markers of age-related changes in goal-directed decision-making under different demands on the representation of state spaces. Our results reveal that the shift to simpler decision strategies in older adults is due to (i) impairments in the representation of the transition structure of the task and (ii) a diminished signaling of the reward value associated with decision options. In line with the diminished state space hypothesis of human aging, our findings suggest that deficits in goal-directed, model-based behavior in older adults result from impairments in the representation of state spaces of cognitive tasks. |
