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PubMed Publications| Keyword search (4,163 papers available) |  |
"Left ventricle" Keyword-tagged Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Experimental Investigation of the Effect of a MitraClip on Left Ventricular Flow Dynamics | Teimouri K; Darwish A; Saleh W; Ng HD; Kadem L; | 40325266 ENCS |
| 2 | An Anatomically Shaped Mitral Valve for Hemodynamic Testing | Darwish A; Papolla C; Rieu R; Kadem L; | 38228812 ENCS |
| 3 | On Left Ventricle Stroke Work Efficiency in Children with Moderate Aortic Valve Regurgitation or Moderate Aortic Valve Stenosis | Asaadi M; Mawad W; Djebbari A; Keshavardz-Motamed Z; Dahdah N; Kadem L; | 34357415 ENCS |
| 4 | Impact of Mitral Regurgitation on the Flow in a Model of a Left Ventricle. | Papolla C, Darwish A, Kadem L, Rieu R | 33000444 ENCS |
| 5 | Experimental Investigation of the Effect of Heart Rate On Flow in the Left Ventricle in Health and Disease -- Aortic Valve Regurgitation. | Di Labbio G, Ben-Assa E, Kadem L | 31701119 ENCS |
| Title: | An Anatomically Shaped Mitral Valve for Hemodynamic Testing | ||||
| Authors: | Darwish A, Papolla C, Rieu R, Kadem L | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/38228812/ | ||||
| DOI: | 10.1007/s13239-024-00714-5 | ||||
| Publication: | Cardiovascular engineering and technology | ||||
| Keywords: | In vitro; Left atrium; Left ventricle; Mitral regurgitation; Mitral valve; Mitral valve prolapse; circulatory loop; | ||||
| PMID: | 38228812 | Category: | Date Added: | 2024-01-17 | |
| Dept Affiliation: |
ENCS
1 Laboratory of Cardiovascular Fluid Dynamics, Concordia University, Montreal, QC, H3G 1M8, Canada. lcfd@encs.concordia.ca. 2 Mechanical Power Engineering Department, Assiut University, Assiut, 71515, Egypt. lcfd@encs.concordia.ca. 3 Laboratory of Cardiovascular Fluid Dynamics, Concordia University, Montreal, QC, H3G 1M8, Canada. 4 Aix-Marseille University, LBA UMR T24, Marseille, France. |
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Description: |
In vitro modeling of the left heart relies on accurately replicating the physiological conditions of the native heart. The targeted physiological conditions include the complex fluid dynamics coming along with the opening and closing of the aortic and mitral valves. As the mitral valve possess a highly sophisticated apparatus, thence, accurately modeling it remained a missing piece in the perfect heart duplicator puzzle. In this study, we explore using a hydrogel-based mitral valve that offers a full representation of the mitral valve apparatus. The valve is tested using a custom-made mock circulatory loop to replicate the left heart. The flow analysis includes performing particle image velocimetry measurements in both left atrium and ventricle. The results showed the ability of the new mitral valve to replicate the real interventricular and atrial flow patterns during the whole cardiac cycle. Moreover, the investigated valve has a ventricular vortex formation time of 5.2, while the peak e- and a-wave ventricular velocities was 0.9 m/s and 0.4 m/s respectively. |
