PERFORM Publications

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Title		Authors	PubMed ID
1	3D bioheat transfer mapping reveals nanomagnetic particles effectiveness in radiofrequency hyperthermia breast cancer treatment comparing to experimental study	Kavousi M; Saadatmand E; Masoumbeigi M; Mahdavi R; Riyahi Alam N;	39557504 PHYSICS
2	Investigation of Macroscopic Mechanical Behavior of Magnetorheological Elastomers under Shear Deformation Using Microscale Representative Volume Element Approach	Abdollahi I; Sedaghati R;	38794567 ENCS
3	Design Optimization of a Hybrid-Driven Soft Surgical Robot with Biomimetic Constraints	Roshanfar M; Dargahi J; Hooshiar A;	38275456 ENCS
4	On the soft tissue ultrasound elastography using FEM based inversion approach	Eshaghinia SS; Taghvaeipour A; Aghdam MM; Rivaz H;	38240143 ENCS
5	The influence of inter-bubble spacing on the resonance response of ultrasound contrast agent microbubbles	Yusefi H; Helfield B;	36223708 BIOLOGY
6	Optical Fiber Array Sensor for Force Estimation and Localization in TAVI Procedure: Design, Modeling, Analysis and Validation	Bandari N; Dargahi J; Packirisamy M;	34450813 ENCS
7	Finite Element Modelling of a Reflection Differential Split-D Eddy Current Probe Scanning Surface Notches.	Mohseni E, França DR, Viens M, Xie WF, Xu B	32214578 ENCS
8	Adaptive Neuro-fuzzy Inference System Trained for Sizing Semi-elliptical Notches Scanned by Eddy Currents.	Mohseni E, Viens M, Xie WF	31929668 ENCS
9	Influence of Head Tissue Conductivity Uncertainties on EEG Dipole Reconstruction.	Vorwerk J, Aydin Ü, Wolters CH, Butson CR	31231178 PERFORM
10	Zoomed MRI Guided by Combined EEG/MEG Source Analysis: A Multimodal Approach for Optimizing Presurgical Epilepsy Work-up and its Application in a Multi-focal Epilepsy Patient Case Study.	Aydin Ü, Rampp S, Wollbrink A, Kugel H, Cho J-, Knösche TR, Grova C, Wellmer J, Wolters CH	28510905 PERFORM

Title:	Zoomed MRI Guided by Combined EEG/MEG Source Analysis: A Multimodal Approach for Optimizing Presurgical Epilepsy Work-up and its Application in a Multi-focal Epilepsy Patient Case Study.
Authors:	Aydin Ü, Rampp S, Wollbrink A, Kugel H, Cho J-, Knösche TR, Grova C, Wellmer J, Wolters CH
Link:	https://www.ncbi.nlm.nih.gov/pubmed/28510905?dopt=Abstract
DOI:	10.1007/s10548-017-0568-9
Publication:	Brain topography
Keywords:	Combined EEG/MEG; Epileptic activity; Focal cortical dysplasia type IIb; Realistic finite element head model; Skull conductivity calibration; Source reconstruction; Zoomed MRI;
PMID:	28510905	Category:	Brain Topogr	Date Added:	2019-06-04
Dept Affiliation:	PERFORM 1 Institute for Biomagnetism und Biosignalanalysis, University of Münster, Malmedyweg 15, 48149, Münster, Germany. umit.aydin@uni-muenster.de. 2 Multimodal Functional Imaging Lab, Department of Physics and PERFORM Centre, Concordia University, Montreal, Quebec, Canada. umit.aydin@uni-muenster.de. 3 Department of Neurosurgery, University Hospital Erlangen, Erlangen, Germany. 4 Institute for Biomagnetism und Biosignalanalysis, University of Münster, Malmedyweg 15, 48149, Münster, Germany. 5 Department of Clinical Radiology, University Hospital Münster, Münster, Germany. 6 Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany. 7 Multimodal Functional Imaging Lab, Department of Physics and PERFORM Centre, Concordia University, Montreal, Quebec, Canada. 8 Multimodal Functional Imaging Lab, Department of Biomedical Engineering, McGill University, Montreal, Quebec, Canada. 9 Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada. 10 Ruhr-Epileptology, Department of Neurology, University Hospital Knappschaftskrankenhaus Bochum, Bochum, Germany.

Description:

Zoomed MRI Guided by Combined EEG/MEG Source Analysis: A Multimodal Approach for Optimizing Presurgical Epilepsy Work-up and its Application in a Multi-focal Epilepsy Patient Case Study.

Brain Topogr. 2017 Jul;30(4):417-433

Authors: Aydin Ü, Rampp S, Wollbrink A, Kugel H, Cho J-, Knösche TR, Grova C, Wellmer J, Wolters CH

Abstract

In recent years, the use of source analysis based on electroencephalography (EEG) and magnetoencephalography (MEG) has gained considerable attention in presurgical epilepsy diagnosis. However, in many cases the source analysis alone is not used to tailor surgery unless the findings are confirmed by lesions, such as, e.g., cortical malformations in MRI. For many patients, the histology of tissue resected from MRI negative epilepsy shows small lesions, which indicates the need for more sensitive MR sequences. In this paper, we describe a technique to maximize the synergy between combined EEG/MEG (EMEG) source analysis and high resolution MRI. The procedure has three main steps: (1) construction of a detailed and calibrated finite element head model that considers the variation of individual skull conductivities and white matter anisotropy, (2) EMEG source analysis performed on averaged interictal epileptic discharges (IED), (3) high resolution (0.5 mm) zoomed MR imaging, limited to small areas centered at the EMEG source locations. The proposed new diagnosis procedure was then applied in a particularly challenging case of an epilepsy patient: EMEG analysis at the peak of the IED coincided with a right frontal focal cortical dysplasia (FCD), which had been detected at standard 1 mm resolution MRI. Of higher interest, zoomed MR imaging (applying parallel transmission, 'ZOOMit') guided by EMEG at the spike onset revealed a second, fairly subtle, FCD in the left fronto-central region. The evaluation revealed that this second FCD, which had not been detectable with standard 1 mm resolution, was the trigger of the seizures.

PMID: 28510905 [PubMed - indexed for MEDLINE]

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