Keyword search (4,164 papers available)

"Son S" Authored Publications:

Title Authors PubMed ID
1 Regioselective Stepwise Synthesis of Unsymmetrical 1,2,5-Triarylpyrroles via Palladium-Catalyzed Decarboxylative Cross-Coupling and C-H Arylation Buonomano C; Patterson S; Ngou JS; Messina C; Taylor S; Bilodeau F; Forgione P; 41900086
CHEMBIOCHEM
2 Clinical Manifestations Gagnon C; Montero-Odasso M; Zou G; Speechley MR; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Bray NW; Li K; Fraser S; Pieruccini-Faria F; Burhan AM; Berryman N; Lussier M; Son S; Shoemaker JK; Bherer L; 41447475
CONCORDIA
3 Public Health Pieruccini-Faria F; Son S; Liu-Ambrose T; Burhan AM; Almeida QJ; Middleton LE; Li K; Fraser S; Bherer L; Montero-Odasso M; 41435121
CONCORDIA
4 Synergistic effects of exercise, cognitive training and vitamin D on gait performance and falls in mild cognitive impairment-secondary outcomes from the SYNERGIC trial Pieruccini-Faria F; Son S; Zou G; Almeida QJ; Middleton LE; Bray NW; Lussier M; Shoemaker JK; Speechley M; Liu-Ambrose T; Burhan AM; Camicioli R; Li KZH; Fraser S; Berryman N; Bherer L; Montero-Odasso M; 40966614
SOH
5 Sequencing of a Dairy Isolate Unlocks em Kluyveromyces marxianus /em as a Host for Lactose Valorization Thornbury M; Knoops A; Summerby-Murray I; Dhaliwal J; Johnson S; Utomo JC; Joshi J; Narcross L; Remondetto G; Pouliot M; Whiteway M; Martin VJJ; 40629255
BIOLOGY
6 Self-Ambivalence Is Indirectly Associated With Obsessive-Compulsive and Eating Disorder Symptoms Through Different Feared Self-Themes Wilson S; Mesli N; Mehak A; Racine SE; 40227164
PSYCHOLOGY
7 Expanding a Behavioral View on Digital Health Access: Drivers and Strategies to Promote Equity Kepper MM; Fowler LA; Kusters IS; Davis JW; Baqer M; Sagui-Henson S; Xiao Y; Tarfa A; Yi JC; Gibson B; Heron KE; Alberts NM; Burgermaster M; Njie-Carr VP; Klesges LM; 39088246
PSYCHOLOGY
8 Feasibility and acceptability of an adapted peer-based walking intervention for adults with moderate-to-severe traumatic brain injury Quilico EL; Wilkinson S; Duncan LR; Sweet SN; Alarie C; Bédard E; Gheta I; Brodeur CL; Colantonio A; Swaine BR; 39051571
CONCORDIA
9 Criminal Code reform of HIV non-disclosure is urgently needed: Social science perspectives on the harms of HIV criminalization in Canada Hastings C; French M; McClelland A; Mykhalovskiy E; Adam B; Bisaillon L; Bogosavljevic K; Gagnon M; Greene S; Guta A; Hindmarch S; Kaida A; Kilty J; Massaquoi N; Namaste V; O' Byrne P; Orsini M; Patterson S; Sanders C; Symington A; Wilson C; 38087186
PSYCHOLOGY
10 Candida albicans exhibits heterogeneous and adaptive cytoprotective responses to anti-fungal compounds Dumeaux V; Massahi S; Bettauer V; Mottola A; Dukovny A; Khurdia SS; Costa ACBP; Omran RP; Simpson S; Xie JL; Whiteway M; Berman J; Hallett MT; 37888959
BIOLOGY
11 Spatial and Temporal Availability of Cloud-free Optical Observations in the Tropics to Monitor Deforestation Flores-Anderson AI; Cardille J; Azad K; Cherrington E; Zhang Y; Wilson S; 37607919
ENCS
12 Effects of Exercise Alone or Combined With Cognitive Training and Vitamin D Supplementation to Improve Cognition in Adults With Mild Cognitive Impairment: A Randomized Clinical Trial Montero-Odasso M; Zou G; Speechley M; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Bray NW; Li KZH; Fraser S; Pieruccini-Faria F; Berryman N; Lussier M; Shoemaker JK; Son S; Bherer L; 37471089
PERFORM
13 COVID-19's impact on a community-based physical activity program for adults with moderate-to-severe TBI Quilico EL; Wilkinson S; Bédard E; Duncan LR; Sweet SN; Swaine BR; Colantonio A; 37184357
AHSC
14 Exploring a peer-based physical activity program in the community for adults with moderate-to-severe traumatic brain injury Quilico E; Sweet S; Duncan L; Wilkinson S; Bonnell K; Alarie C; Swaine B; Colantonio A; 37157834
AHSC
15 A metagenomic-based study of two sites from the Barbadian reef system Simpson S; Bettauer V; Ramachandran A; Kraemer S; Mahon S; Medina M; Vallès Y; Dumeaux V; Vallès H; Walsh D; Hallett MT; 37009568
BIOLOGY
16 Participatory co-creation of an adapted physical activity program for adults with moderate-to-severe traumatic brain injury Quilico E; Wilkinson S; Duncan L; Sweet S; Bédard E; Trudel E; Colantonio A; Swaine B; 36188895
AHSC
17 A Deep Learning Approach to Capture the Essence of Candida albicans Morphologies Bettauer V; Costa ACBP; Omran RP; Massahi S; Kirbizakis E; Simpson S; Dumeaux V; Law C; Whiteway M; Hallett MT; 35972285
BIOLOGY
18 Mutations in TRAPPC12 Manifest in Progressive Childhood Encephalopathy and Golgi Dysfunction. Milev MP, Grout ME, Saint-Dic D, Cheng YH, Glass IA, Hale CJ, Hanna DS, Dorschner MO, Prematilake K, Shaag A, Elpeleg O, Sacher M, Doherty D, Edvardson S 28777934
BIOLOGY
19 Parental Nutrition Knowledge Rather Than Nutrition Label Use Is Associated With Adiposity in Children. Kakinami L, Houle-Johnson S, McGrath JJ 27373860
PERFORM

 

Title:Public Health
Authors:Pieruccini-Faria FSon SLiu-Ambrose TBurhan AMAlmeida QJMiddleton LELi KFraser SBherer LMontero-Odasso M
Link:https://pubmed.ncbi.nlm.nih.gov/41435121/
DOI:10.1002/alz70860_103664
Publication:Alzheimer s & dementia : the journal of the Alzheimer s Association
Keywords:
PMID:41435121 Category: Date Added:2025-12-23
Dept Affiliation: CONCORDIA
1 Gait and Brain Laboratory, Parkwood Institute, London, ON, Canada.
2 Gait & Brain Lab; Lawson Research Institute; Schulich School of Medicine& Dentistry, Division of Geriatric Medicine, Western University, London, ON, Canada.
3 Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
4 Parkwood Institute, London, ON, Canada.
5 Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.
6 Centre for Aging SMART, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.
7 University of British Columbia, Vancouver, BC, Canada.
8 Djavad Mowafaghian Centre for Brain Health, Vancouver, BC, Canada.
9 University of Toronto, Toronto, ON, Canada.
10 Care Space Health, Waterloo, ON, Canada.
11 Schlegel-UW Research Institute for Aging, Waterloo, ON, Canada.
12 University of Waterloo, Waterloo, ON, Canada.
13 Concordia University, Montreal, QC, Canada.
14 University of Ottawa, Ottawa, ON, Canada.
15 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, QC, Canada.
16 University of Montreal, Montreal, QC, Canada.
17 Schulich School of Medicine & Dentistry, Division of Geriatric Medicine, Western University, London, ON, Canada.

Description:

Background: Mild Cognitive Impairment (MCI) may be associated with the presence of the apolipoprotein E4 allele (APOE4), a genetic factor linked to accelerated cognitive decline. The SYNERGIC trial demonstrated that physical exercise (PE) involving aerobic and resistance training improves global cognition in individuals with MCI, with significantly enhanced benefits of cognitive training but not vitamin D. The role of APOE4 status in responsiveness to these interventions remains unclear.

Method: Of 175 participants in the SYNERGIC trial, 80 underwent APOE4 genotyping. This study analyzed 67 participants (mean age: 73.8 years; 43.2% women) who completed a 6-month multidomain intervention across four arms: (1) PE + Cognitive training (Neuropeak®) + Vitamin D; (2) PE + Cognitive training; (3) PE + Vitamin D; and (4) PE alone. Changes in global cognition (ADAS-Cog-13) were compared between APOE4-positive and APOE4-negative individuals using ANOVA.

Result: APOE4-positive participants showed attenuated global cognitive improvements from multidomain interventions compared to APOE4-negative participants (mean difference = -2.08, 95% CI: -4.18 to 0.11; p = 0.052; d = -0.56). A significant group effect (p = 0.03) revealed that the PE + Vitamin D arm worsened global cognition over time compared to all other arms, with significant decline relative to the arm receiving all three interventions (p = 0.02). Sensitivity analysis excluding arms with vitamin D confirmed the attenuated effect of APOE4-positive status on global cognition (mean difference = -2.99, 95% CI: -6.10 to 0.11; p = 0.05; d = -0.78).

Conclusion: Individuals with MCI and APOE4-positive status exhibit reduced responsiveness to multidomain interventions for global cognition, likely due to underlying genetic neurodegeneration.





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