Keyword search (4,163 papers available)

"Pomares FB" Authored Publications:

Title Authors PubMed ID
1 The effectiveness of Cognitive behavioral therapy for insomnia on sleep EEG hyperarousal: a multicentric polysomnographic study Sforza M; Morin CM; Dang-Vu TT; Pomares FB; Perrault AA; Gouin JP; Bušková J; Janku K; Vgontzas A; Fernandez-Mendoza J; Bastien CH; Riemann D; Baglioni C; Carollo G; Casoni F; Zucconi M; Castronovo V; Galbiati A; Ferini-Strambi L; 41688421
SOH
2 Identification of five sleep-biopsychosocial profiles with specific neural signatures linking sleep variability with health, cognition, and lifestyle factors Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Yeo BTT; 41056215
HKAP
3 Effect of chronic benzodiazepine and benzodiazepine receptor agonist use on sleep architecture and brain oscillations in older adults with chronic insomnia Barbaux L; Perrault AA; Cross NE; Weiner OM; Es-Sounni M; Pomares FB; Tarelli L; McCarthy M; Maltezos A; Smith D; Gong K; O' Byrne J; Yue V; Desrosiers C; Clerc D; Andriamampionona F; Lussier D; Gilbert S; Tannenbaum C; Gouin JP; Dang-Vu TT; 40570297
CSBN
4 Cognitive-behavioural therapy for insomnia mechanism of action: Exploring the homeostatic K-complex involvement Sforza M; Morin CM; Dang-Vu TT; Pomares FB; Perrault AA; Gouin JP; Bušková J; Janku K; Vgontzas A; Fernandez-Mendoza J; Bastien CH; Riemann D; Baglioni C; Carollo G; Casoni F; Zucconi M; Castronovo V; Galbiati A; Ferini-Strambi L; 39739397
SOH
5 NREM sleep brain networks modulate cognitive recovery from sleep deprivation Lee K; Wang Y; Cross NE; Jegou A; Razavipour F; Pomares FB; Perrault AA; Nguyen A; Aydin Ü; Uji M; Abdallah C; Anticevic A; Frauscher B; Benali H; Dang-Vu TT; Grova C; 39005401
PERFORM
6 A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Yeo BTT; 38659875
HKAP
7 A multidimensional investigation of sleep and biopsychosocialprofiles with associated neural signatures Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Thomas Yeo BT; 38559143
HKAP
8 Methodological approach to sleep state misperception in insomnia disorder: Comparison between multiple nights of actigraphy recordings and a single night of polysomnography recording Maltezos A; Perrault AA; Walsh NA; Phillips EM; Gong K; Tarelli L; Smith D; Cross NE; Pomares FB; Gouin JP; Dang-Vu TT; 38325157
HKAP
9 Effects of cognitive behavioral therapy for insomnia on subjective and objective measures of sleep and cognition Perrault AA; Pomares FB; Smith D; Cross NE; Gong K; Maltezos A; McCarthy M; Madigan E; Tarelli L; McGrath JJ; Savard J; Schwartz S; Gouin JP; Dang-Vu TT; 35691208
PERFORM
10 An altered balance of integrated and segregated brain activity is a marker of cognitive deficits following sleep deprivation Cross NE; Pomares FB; Nguyen A; Perrault AA; Jegou A; Uji M; Lee K; Razavipour F; Ali OBK; Aydin U; Benali H; Grova C; Dang-Vu TT; 34735431
PERFORM
11 Data-driven beamforming technique to attenuate ballistocardiogram artefacts in electroencephalography-functional magnetic resonance imaging without detecting cardiac pulses in electrocardiography recordings Uji M; Cross N; Pomares FB; Perrault AA; Jegou A; Nguyen A; Aydin U; Lina JM; Dang-Vu TT; Grova C; 34101939
PERFORM
12 Cortical gradients of functional connectivity are robust to state-dependent changes following sleep deprivation. Cross N; Paquola C; Pomares FB; Perrault AA; Jegou A; Nguyen A; Aydin U; Bernhardt BC; Grova C; Dang-Vu TT; 33186718
PERFORM
13 DNA methylation differences in stress-related genes, functional connectivity and gray matter volume in depressed and healthy adolescents. Chiarella J, Schumann L, Pomares FB, Frodl T, Tozzi L, Nemoda Z, Yu P, Szyf M, Khalid-Khan S, Booij L 32479312
PSYCHOLOGY
14 Neuropathic pain after thoracotomy: tracking signs and symptoms before and at monthly intervals following surgery. Gandhi W, Pomares FB, Naso L, Asenjo JF, Schweinhardt P 32267038
PSYCHOLOGY
15 Beyond sleepy: structural and functional changes of the default-mode network in idiopathic hypersomnia. Pomares FB, Boucetta S, Lachapelle F, Steffener J, Montplaisir J, Cha J, Kim H, Dang-Vu TT 31328786
PERFORM
16 Serotonin transporter gene promoter methylation in peripheral cells in healthy adults: Neural correlates and tissue specificity. Ismaylova E, Di Sante J, Szyf M, Nemoda Z, Yu WJ, Pomares FB, Turecki G, Gobbi G, Vitaro F, Tremblay RE, Booij L 28774705
PSYCHOLOGY
17 Epigenetic Changes of FKBP5 as a Link Connecting Genetic and Environmental Risk Factors with Structural and Functional Brain Changes in Major Depression. Tozzi L, Farrell C, Booij L, Doolin K, Nemoda Z, Szyf M, Pomares FB, Chiarella J, O'Keane V, Frodl T 29182159
PSYCHOLOGY
18 Associations Between Daily Mood States and Brain Gray Matter Volume, Resting-State Functional Connectivity and Task-Based Activity in Healthy Adults. Ismaylova E, Di Sante J, Gouin JP, Pomares FB, Vitaro F, Tremblay RE, Booij L 29765312
PSYCHOLOGY
19 Serotonin transporter promoter methylation in peripheral cells and neural responses to negative stimuli: A study of adolescent monozygotic twins. Ismaylova E, Lévesque ML, Pomares FB, Szyf M, Nemoda Z, Fahim C, Vitaro F, Brendgen M, Dionne G, Boivin M, Tremblay RE, Booij L 30089832
PSYCHOLOGY

 

Title:DNA methylation differences in stress-related genes, functional connectivity and gray matter volume in depressed and healthy adolescents.
Authors:Chiarella JSchumann LPomares FBFrodl TTozzi LNemoda ZYu PSzyf MKhalid-Khan SBooij L
Link:https://www.ncbi.nlm.nih.gov/pubmed/32479312?dopt=Abstract
DOI:10.1016/j.jad.2020.03.062
Publication:Journal of affective disorders
Keywords:Adolescent depressionBrain structureDNA methylationEpigeneticsFunctional connectivity
PMID:32479312 Category:J Affect Disord Date Added:2020-06-02
Dept Affiliation: PSYCHOLOGY
1 Department of Psychology, Concordia University, Montreal, Canada; CHU Sainte-Justine Hospital Research Centre, University of Montreal, Montreal, Canada; Department of Psychology, Queen's University, Kingston, Canada.
2 Department of Psychology, Queen's University, Kingston, Canada.
3 Department of Psychology, Concordia University, Montreal, Canada.
4 Department of Psychiatry and Psychotherapy, Otto von Guericke University, Magdeburg, Germany.
5 Department of Psychiatry, Trinity College School of Medicine and Trinity College Institute of Neuroscience, Dublin, Ireland.
6 Department of Psychology, Concordia University, Montreal, Canada; Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada; Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary.
7 Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada.
8 Department of Psychiatry, Division of Child Psychiatry, Hotel Dieu Hospital, Queen's University, Kingston, Canada.
9 Department of Psychology, Concordia University, Montreal, Canada; CHU Sainte-Justine Hospital Research Centre, University of Montreal, Montreal, Canada; Department of Psychology, Queen's University, Kingston, Canada. Electronic address: linda.booij@concordia.ca.

Description:

DNA methylation differences in stress-related genes, functional connectivity and gray matter volume in depressed and healthy adolescents.

J Affect Disord. 2020 Jun 15;271:160-168

Authors: Chiarella J, Schumann L, Pomares FB, Frodl T, Tozzi L, Nemoda Z, Yu P, Szyf M, Khalid-Khan S, Booij L

Abstract

BACKGROUND: Studies in adult depressed patients have indicated that altered DNA methylation patterns at genes related to serotonin and HPA axis functioning (e.g., SLC6A4, FKBP5) are associated with changes in frontolimbic functional connectivity and structure. Here, we examined whether these associations can be generalized to adolescents.

METHODS: 25 adolescents with depression (Mean age = 15.72 ± 0.94 SD; 20 girls) and 20 healthy controls (Mean age = 16.05 ± 1.5 SD; 16 girls) underwent a functional and structural magnetic resonance imaging protocol, which included a resting-state assessment and measures of brain morphometry. DNA was obtained from saliva. Levels of SLC6A4 and FKBP5 methylation were determined using pyrosequencing.

RESULTS: SLC6A4 methylation was linked to amygdala-frontal operculum resting-state functional connectivity (rs-FC), regardless of diagnosis, and was differentially associated with inferior orbitofrontal gyrus (IFOG) gray matter (GM) volume in adolescents with depression and controls. Replicating and extending previous findings in adults, FKBP5 methylation was associated with IFOG GM volume in depressed and healthy adolescents, as well as orbitofrontal cortex (OFC)-rostral prefrontal cortex (RPFC) connectivity in healthy adolescents only.

LIMITATIONS: Effects of medication use or genotype cannot be ruled out. Further, the relatively small sample size and predominately female sample may limit generalizability.

CONCLUSIONS: These findings suggest that previously observed associations between SLC6A4 and FKBP5 methylation and frontolimbic processes in adult depressed patients can be in part generalized to adolescent patients. Further, findings suggest that measuring peripheral methylation at these genes deserves further attention as potential markers of typical and atypical development.

PMID: 32479312 [PubMed - as supplied by publisher]





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