Keyword search (4,163 papers available)

"Pomares FB" Authored Publications:

Title Authors PubMed ID
1 The effectiveness of Cognitive behavioral therapy for insomnia on sleep EEG hyperarousal: a multicentric polysomnographic study Sforza M; Morin CM; Dang-Vu TT; Pomares FB; Perrault AA; Gouin JP; Bušková J; Janku K; Vgontzas A; Fernandez-Mendoza J; Bastien CH; Riemann D; Baglioni C; Carollo G; Casoni F; Zucconi M; Castronovo V; Galbiati A; Ferini-Strambi L; 41688421
SOH
2 Identification of five sleep-biopsychosocial profiles with specific neural signatures linking sleep variability with health, cognition, and lifestyle factors Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Yeo BTT; 41056215
HKAP
3 Effect of chronic benzodiazepine and benzodiazepine receptor agonist use on sleep architecture and brain oscillations in older adults with chronic insomnia Barbaux L; Perrault AA; Cross NE; Weiner OM; Es-Sounni M; Pomares FB; Tarelli L; McCarthy M; Maltezos A; Smith D; Gong K; O' Byrne J; Yue V; Desrosiers C; Clerc D; Andriamampionona F; Lussier D; Gilbert S; Tannenbaum C; Gouin JP; Dang-Vu TT; 40570297
CSBN
4 Cognitive-behavioural therapy for insomnia mechanism of action: Exploring the homeostatic K-complex involvement Sforza M; Morin CM; Dang-Vu TT; Pomares FB; Perrault AA; Gouin JP; Bušková J; Janku K; Vgontzas A; Fernandez-Mendoza J; Bastien CH; Riemann D; Baglioni C; Carollo G; Casoni F; Zucconi M; Castronovo V; Galbiati A; Ferini-Strambi L; 39739397
SOH
5 NREM sleep brain networks modulate cognitive recovery from sleep deprivation Lee K; Wang Y; Cross NE; Jegou A; Razavipour F; Pomares FB; Perrault AA; Nguyen A; Aydin Ü; Uji M; Abdallah C; Anticevic A; Frauscher B; Benali H; Dang-Vu TT; Grova C; 39005401
PERFORM
6 A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Yeo BTT; 38659875
HKAP
7 A multidimensional investigation of sleep and biopsychosocialprofiles with associated neural signatures Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Thomas Yeo BT; 38559143
HKAP
8 Methodological approach to sleep state misperception in insomnia disorder: Comparison between multiple nights of actigraphy recordings and a single night of polysomnography recording Maltezos A; Perrault AA; Walsh NA; Phillips EM; Gong K; Tarelli L; Smith D; Cross NE; Pomares FB; Gouin JP; Dang-Vu TT; 38325157
HKAP
9 Effects of cognitive behavioral therapy for insomnia on subjective and objective measures of sleep and cognition Perrault AA; Pomares FB; Smith D; Cross NE; Gong K; Maltezos A; McCarthy M; Madigan E; Tarelli L; McGrath JJ; Savard J; Schwartz S; Gouin JP; Dang-Vu TT; 35691208
PERFORM
10 An altered balance of integrated and segregated brain activity is a marker of cognitive deficits following sleep deprivation Cross NE; Pomares FB; Nguyen A; Perrault AA; Jegou A; Uji M; Lee K; Razavipour F; Ali OBK; Aydin U; Benali H; Grova C; Dang-Vu TT; 34735431
PERFORM
11 Data-driven beamforming technique to attenuate ballistocardiogram artefacts in electroencephalography-functional magnetic resonance imaging without detecting cardiac pulses in electrocardiography recordings Uji M; Cross N; Pomares FB; Perrault AA; Jegou A; Nguyen A; Aydin U; Lina JM; Dang-Vu TT; Grova C; 34101939
PERFORM
12 Cortical gradients of functional connectivity are robust to state-dependent changes following sleep deprivation. Cross N; Paquola C; Pomares FB; Perrault AA; Jegou A; Nguyen A; Aydin U; Bernhardt BC; Grova C; Dang-Vu TT; 33186718
PERFORM
13 DNA methylation differences in stress-related genes, functional connectivity and gray matter volume in depressed and healthy adolescents. Chiarella J, Schumann L, Pomares FB, Frodl T, Tozzi L, Nemoda Z, Yu P, Szyf M, Khalid-Khan S, Booij L 32479312
PSYCHOLOGY
14 Neuropathic pain after thoracotomy: tracking signs and symptoms before and at monthly intervals following surgery. Gandhi W, Pomares FB, Naso L, Asenjo JF, Schweinhardt P 32267038
PSYCHOLOGY
15 Beyond sleepy: structural and functional changes of the default-mode network in idiopathic hypersomnia. Pomares FB, Boucetta S, Lachapelle F, Steffener J, Montplaisir J, Cha J, Kim H, Dang-Vu TT 31328786
PERFORM
16 Serotonin transporter gene promoter methylation in peripheral cells in healthy adults: Neural correlates and tissue specificity. Ismaylova E, Di Sante J, Szyf M, Nemoda Z, Yu WJ, Pomares FB, Turecki G, Gobbi G, Vitaro F, Tremblay RE, Booij L 28774705
PSYCHOLOGY
17 Epigenetic Changes of FKBP5 as a Link Connecting Genetic and Environmental Risk Factors with Structural and Functional Brain Changes in Major Depression. Tozzi L, Farrell C, Booij L, Doolin K, Nemoda Z, Szyf M, Pomares FB, Chiarella J, O'Keane V, Frodl T 29182159
PSYCHOLOGY
18 Associations Between Daily Mood States and Brain Gray Matter Volume, Resting-State Functional Connectivity and Task-Based Activity in Healthy Adults. Ismaylova E, Di Sante J, Gouin JP, Pomares FB, Vitaro F, Tremblay RE, Booij L 29765312
PSYCHOLOGY
19 Serotonin transporter promoter methylation in peripheral cells and neural responses to negative stimuli: A study of adolescent monozygotic twins. Ismaylova E, Lévesque ML, Pomares FB, Szyf M, Nemoda Z, Fahim C, Vitaro F, Brendgen M, Dionne G, Boivin M, Tremblay RE, Booij L 30089832
PSYCHOLOGY

 

Title:Serotonin transporter promoter methylation in peripheral cells and neural responses to negative stimuli: A study of adolescent monozygotic twins.
Authors:Ismaylova ELévesque MLPomares FBSzyf MNemoda ZFahim CVitaro FBrendgen MDionne GBoivin MTremblay REBooij L
Link:https://www.ncbi.nlm.nih.gov/pubmed/30089832?dopt=Abstract
DOI:10.1038/s41398-018-0195-6
Publication:Translational psychiatry
Keywords:
PMID:30089832 Category:Transl Psychiatry Date Added:2019-06-20
Dept Affiliation: PSYCHOLOGY
1 CHU Sainte-Justine Research Centre, Montreal, Canada.
2 Department of Psychiatry, University of Montreal, Montreal, Canada.
3 Department of Psychology, Concordia University, Montreal, Canada.
4 Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada.
5 School of Psychoeducation, University of Montreal, Montreal, Canada.
6 Department of Psychology, University of Quebec à Montreal, Montreal, Canada.
7 School of Psychology, University of Laval, Quebec, Canada.
8 Institute of Genetic, Neurobiological, and Social Foundations of Child Development, Tomsk State University, Tomsk, Russian Federation.
9 Department of Psychology, University of Montreal, Montreal, Canada.
10 School of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland.
11 CHU Sainte-Justine Research Centre, Montreal, Canada. linda.booij@concordia.ca.
12 Department of Psychiatry, University of Montreal, Montreal, Canada. linda.booij@concordia.ca.
13 Department of Psychology, Concordia University, Montreal, Canada. linda.booij@concordia.ca.

Description:

Serotonin transporter promoter methylation in peripheral cells and neural responses to negative stimuli: A study of adolescent monozygotic twins.

Transl Psychiatry. 2018 08 08;8(1):147

Authors: Ismaylova E, Lévesque ML, Pomares FB, Szyf M, Nemoda Z, Fahim C, Vitaro F, Brendgen M, Dionne G, Boivin M, Tremblay RE, Booij L

Abstract

Several studies have examined associations between peripheral DNA methylation patterns of the serotonin transporter gene (SLC6A4) promoter and symptoms of depression and anxiety. The SLC6A4 promoter methylation has also been associated with frontal-limbic brain responses to negative stimuli. However, it is unclear how much of this association is confounded by DNA sequence variations. We utilized a monozygotic-twin within-pair discordance design, to test whether DNA methylation at specific CpG sites in the SLC6A4 promoter of peripheral cells is associated with greater frontal-limbic brain responses to negative stimuli (sadness and fear), independently of DNA sequence effects. In total 48 pairs of healthy 15-year-old monozygotic twins from the Quebec Newborn Twin Study, followed regularly since birth, underwent functional magnetic resonance imaging while conducting an emotion-processing task. The SLC6A4 promoter methylation level was assessed in saliva samples using pyrosequencing. Relative to the co-twins with lower SLC6A4 promoter methylation levels, twins with higher peripheral SLC6A4 methylation levels showed greater orbitofrontal cortical (OFC) activity and left amygdala-anterior cingulate cortex (ACC) and left amygdala-right OFC connectivity in response to sadness as well as greater ACC-left amygdala and ACC-left insula connectivity in response to fearful stimuli. By utilising a monozygotic-twin design, we provided evidence that associations between peripheral SLC6A4 promoter methylation and frontal-limbic brain responses to negative stimuli are, in part, independent of DNA sequence variations. Although causality cannot be determined here, SLC6A4 promoter methylation may be one of the mechanisms underlying how environmental factors influence the serotonin system, potentially affecting emotional processing through frontal-limbic areas.

PMID: 30089832 [PubMed - indexed for MEDLINE]





BookR developed by Sriram Narayanan
for the Concordia University School of Health
Copyright © 2011-2026
Cookie settings
Concordia University