PERFORM Publications

Keyword search (4,163 papers available)

Title		Authors	PubMed ID
1	Thermo-responsive polysulfobetaine beads crosslinked with biodegradable alginates for controlled release of agricultural pesticide	Andrade-Gagnon B; Olszewski C; Bawa KK; Hemraz UD; Oh JK;	41561011 CHEMBIOCHEM
2	Synthesis and Acidic pH-Responsive Disassembly of Dual-Location Shell-Sheddable/Core-Degradable Block Copolymer Nanoassemblies and Their Controlled Drug Delivery	Andrade-Gagnon B; Casillas-Popova SN; Shamekhi M; Bairagi K; Peslherbe GH; Oh JK;	41524627 CHEMBIOCHEM
3	Luminescent Electro-Spun Nanofibers Crosslinked with Boronic Esters Exhibiting Controlled Release of Carbon Dots for Detection of Wound pHs and Enhanced Antimicrobial	Lokuge ND; Casillas-Popova SN; Singh P; Clermont-Paquette A; Skinner CD; Findlay BL; Naccache R; Oh JK;	40920389 BIOLOGY
4	Development of dual acid-visible light-degradable core-crosslinked nanogels with extended conjugate aromatic imines for enhanced drug delivery	Bairagi K; Shamekhi M; Tountas I; Letourneau N; Peslherbe GH; Piekny A; Oh JK;	40637173 BIOLOGY
5	Stability of Acetals/Ketals Under Controlled Radical and Ring Opening Polymerization	Andrade-Gagnon B; Casillas-Popova SN; Oh JK;	40614241 CHEMBIOCHEM
6	Multi-stimuli-responsive degradable boronic ester-crosslinked e-spun nanofiber wound dressings	Casillas-Popova SN; Lokuge ND; Singh P; Cirillo A; Thinphang-Nga A; Skinner CD; Vuckovic D; Findlay BL; Oh JK;	40557709 BIOLOGY
7	Research Trends in the Development of Block Copolymer-Based Biosensing Platforms	Chung YH; Oh JK;	39590001 CHEMBIOCHEM
8	pH-Responsive Degradable Electro-Spun Nanofibers Crosslinked via Boronic Ester Chemistry for Smart Wound Dressings	Casillas-Popova SN; Lokuge ND; Andrade-Gagnon B; Chowdhury FR; Skinner CD; Findlay BL; Oh JK;	38989606 BIOLOGY
9	Fabrication of thermo-responsive multicore microcapsules using a facile extrusion process	Lavertu JD; Bawa KK; Hrapovic S; Fu D; Oh JK; Hemraz UD;	38915334 CHEMBIOCHEM
10	Design, Synthesis, and Acid-Responsive Disassembly of Shell-Sheddable Block Copolymer Labeled with Benzaldehyde Acetal Junction	Andrade-Gagnon B; Casillas-Popova SN; Jazani AM; Oh JK;	38499007 CHEMBIOCHEM
11	Preparation of a Convertible Spacer Containing a Disulfide Group for Versatile Functionalization of Oligonucleotides	Pontarelli A; Liu JT; Oh JK; Wilds CJ;	36840706 CHEMBIOCHEM
12	Dual acting acid-cleavable self-assembling prodrug from hyaluronic acid and ciprofloxacin: A potential system for simultaneously targeting bacterial infections and cancer	Ibrahim UH; Devnarain N; Mohammed M; Omolo CA; Gafar MA; Salih M; Pant A; Shunmugam L; Mocktar C; Khan R; Oh JK; Govender T;	36150574 CHEMBIOCHEM
13	Synthesis of a Convertible Linker Containing a Disulfide Group for Oligonucleotide Functionalization	Pontarelli A; Liu JT; Movasat H; Ménard S; Oh JK; Wilds CJ;	35863757 CHEMBIOCHEM
14	Perfluorocarbon Nanodroplets for Dual Delivery with Ultrasound/GSH-Responsive Release of Model Drug and Passive Release of Nitric Oxide	Choi M; Jazani AM; Oh JK; Noh SM;	35683912 CHEMBIOCHEM
15	Dynamic and Reprocessable Fluorinated Poly(hindered urea) Network Materials Containing Ionic Liquids to Enhance Triboelectric Performance	Nellepalli P; Kim MP; Park J; Noh SM; Ye Z; Jung HW; Ko H; Oh JK;	35385641 CHEMBIOCHEM
16	Electrospun Upconverting Nanofibrous Hybrids with Smart NIR-Light-Controlled Drug Release for Wound Dressing	Huang HY; Skripka A; Zaroubi L; Findlay BL; Vetrone F; Skinner C; Oh JK; Cuccia LA;	35019380 CHEMBIOCHEM
17	Dynamic Covalent Polyurethane Network Materials: Synthesis and Self-healability	Nellepalli P; Patel T; Oh JK;	34418209 CHEMBIOCHEM
18	Designing Ultrasmall Carbon Nanospheres with Tailored Sizes and Textural Properties for High-Rate High-Energy Supercapacitors	Liu X; Vadiyar MM; Oh JK; Ye Z;	34229427 CHEMBIOCHEM
19	Imidazole-Mediated Dual Location Disassembly of Acid-Degradable Intracellular Drug Delivery Block Copolymer Nanoassemblies	Jazani AM; Shetty C; Movasat H; Bawa KK; Oh JK;	34050688 CHEMBIOCHEM
20	Macromolecularly Engineered Thermoreversible Heterogeneous Self-Healable Networks Encapsulating Reactive Multidentate Block Copolymer-Stabilized Carbon Nanotubes	Zhang G; Patel T; Nellepalli P; Bhagat S; Hase H; Jazani AM; Salzmann I; Ye Z; Oh JK;	33988899 CHEMBIOCHEM
21	Microfluidic Shear Processing Control of Biological Reduction Stimuli-Responsive Polymer Nanoparticles for Drug Delivery.	Huang Y, Jazani AM, Howell EP, Reynolds LA, Oh JK, Moffitt MG	33455300 CHEMBIOCHEM
22	Controlled Microfluidic Synthesis of Biological Stimuli-Responsive Polymer Nanoparticles.	Huang Y, Moini Jazani A, Howell EP, Oh JK, Moffitt MG	31820915 CHEMBIOCHEM
23	Direct Polymerization Approach to Synthesize Acid-Degradable Block Copolymers Bearing Imine Pendants for Tunable pH-Sensitivity and Enhanced Release.	Hu X, Oh JK	32964550 CHEMBIOCHEM
24	Self-Healable Reprocessable Triboelectric Nanogenerators Fabricated with Vitrimeric Poly(hindered Urea) Networks.	Patel T, Kim MP, Park J, Lee TH, Nellepalli P, Noh SM, Jung HW, Ko H, Oh JK	32840992 CHEMBIOCHEM
25	Dual Reduction/Acid-Responsive Disassembly and Thermoresponsive Tunability of Degradable Double Hydrophilic Block Copolymer.	Maruya-Li K, Shetty C, Moini Jazani A, Arezi N, Oh JK	32118189 CHEMBIOCHEM
26	Facile Strategies to Synthesize Dual Location Dual Acidic pH/Reduction-Responsive Degradable Block Copolymers Bearing Acetal/Disulfide Block Junctions and Disulfide Pendants.	Jazani AM, Arezi N, Maruya-Li K, Jung S, Oh JK	31459031 CHEMBIOCHEM
27	Reduction-Responsive Sheddable Carbon Nanotubes Dispersed in Aqueous Solution.	An SY, Sun S, Oh JK	26890479 CNSR
28	Intracellular Delivery of Colloidally Stable Core-Cross-Linked Triblock Copolymer Micelles with Glutathione-Responsive Enhanced Drug Release for Cancer Therapy.	Biswas D, An SY, Li Y, Wang X, Oh JK	28207270 CHEMBIOCHEM
29	Multiblock Copolymer-Based Dual Dynamic Disulfide and Supramolecular Crosslinked Self-Healing Networks.	An SY, Noh SM, Oh JK	28221703 CHEMBIOCHEM
30	Enhancing targeted antibiotic therapy via pH responsive solid lipid nanoparticles from an acid cleavable lipid.	Kalhapure RS, Sikwal DR, Rambharose S, Mocktar C, Singh S, Bester L, Oh JK, Renukuntla J, Govender T	28434930 CHEMBIOCHEM
31	Stimulus-Responsive Degradable Polylactide-Based Block Copolymer Nanoassemblies for Controlled/Enhanced Drug Delivery.	Bawa KK, Oh JK	28493712 CHEMBIOCHEM
32	Polymers in Drug Delivery: Chemistry and Applications.	Oh JK	28780874 CHEMBIOCHEM
33	Thermally Labile Self-Healable Branched Gel Networks Fabricated by New Macromolecular Engineering Approach Utilizing Thermoreversibility.	Jung S, Patel T, Oh JK	29210490 CHEMBIOCHEM
34	Microfluidic Assembly To Synthesize Dual Enzyme/Oxidation-Responsive Polyester-Based Nanoparticulates with Controlled Sizes for Drug Delivery.	Hong SH, Patel T, Ip S, Garg S, Oh JK	29485889 CHEMBIOCHEM
35	Dual disassembly and biological evaluation of enzyme/oxidation-responsive polyester-based nanoparticulates for tumor-targeting delivery.	Hong SH, Larocque K, Jaunky DB, Piekny A, Oh JK	30223243 CHEMBIOCHEM
36	PLA-Based Triblock Copolymer Micelles Exhibiting Dual Acidic pH/Reduction Responses at Dual Core and Core/Corona Interface Locations.	Bawa KK, Jazani AM, Shetty C, Oh JK	30286258 CHEMBIOCHEM
37	Multifunctional Self-Assembled Supernanoparticles for Deep-Tissue Bimodal Imaging and Amplified Dual-Mode Heating Treatment.	Yang F, Skripka A, Tabatabaei MS, Hong SH, Ren F, Benayas A, Oh JK, Martel S, Liu X, Vetrone F, Ma D	30604607 CHEMBIOCHEM

Title:	Intracellular Delivery of Colloidally Stable Core-Cross-Linked Triblock Copolymer Micelles with Glutathione-Responsive Enhanced Drug Release for Cancer Therapy.
Authors:	Biswas D, An SY, Li Y, Wang X, Oh JK
Link:	https://www.ncbi.nlm.nih.gov/pubmed/28207270?dopt=Abstract
Publication:
Keywords:
PMID:	28207270	Category:	Mol Pharm	Date Added:	2019-05-31
Dept Affiliation:	CHEMBIOCHEM 1 Department of Chemistry and Biochemistry, Concordia University , Montreal, Quebec Canada H4B 1R6. 2 Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College , No. 151, Malianwa North Road, Haidian District, Beijing 100193, China.

Description:

Intracellular Delivery of Colloidally Stable Core-Cross-Linked Triblock Copolymer Micelles with Glutathione-Responsive Enhanced Drug Release for Cancer Therapy.

Mol Pharm. 2017 08 07;14(8):2518-2528

Authors: Biswas D, An SY, Li Y, Wang X, Oh JK

Abstract

Design and development of amphiphilic block copolymer-based nanocarriers exhibiting enhanced colloidal stability upon dilution in the blood and cellular glutathione-responsive rapid drug release is highly desired for tumor-targeting chemotherapy. Herein, we report a novel ABA-type triblock copolymer consisting of a hydrophilic central poly(ethylene glycol) block and two terminal hydrophobic blocks of a polymethacrylate having pendant disulfides (PHMssEt), thus PHMssEt-b-PEG-b-PHMssEt (ssTP). Aqueous self-assembly and the following disulfide-exchange reaction of the resulting ssTP allow for formation of core-cross-linked micelles (CCMs) through the formation of new disulfide linkages, retaining enhanced colloidal stability in physiological conditions and in the presence of proteins. Further, they exhibit reduction-responsive enhanced release of encapsulated drugs in response to cellular concentrations of glutathione in cancer cells, confirmed by dynamic light scattering and spectroscopic analysis. Combined with these results, in vitro (cells) and in vivo (mouse model) biological results suggest that ssTP-based CCMs are effective candidates as intracellular nanocarriers targeting tumors for cancer therapy.

PMID: 28207270 [PubMed - indexed for MEDLINE]

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