Keyword search (4,164 papers available)

"Morais JA" Authored Publications:

Title Authors PubMed ID
1 The age of obesity onset affects changes in subcutaneous adipose tissue macrophages and T cells after weight loss Murphy J; Morais JA; Tsoukas MA; Cooke AB; Daskalopoulou SS; Santosa S; 40831565
SOH
2 Intramyocellular lipid use is altered with exercise in males with childhood-onset obesity despite no differences in substrate oxidation Feola S; Al-Nabelsi L; Tam BT; Near J; Morais JA; Santosa S; 39875595
HKAP
3 Age of obesity onset affects subcutaneous adipose tissue cellularity differently in the abdominal and femoral region Murphy J; Dera A; Morais JA; Tsoukas MA; Khor N; Sazonova T; Almeida LG; Cooke AB; Daskalopoulou SS; Tam BT; Santosa S; 39045668
SOH
4 Senescence markers in subcutaneous preadipocytes differ in childhood- versus adult-onset obesity before and after weight loss Murphy J; Tam BT; Kirkland JL; Tchkonia T; Giorgadze N; Pirtskhalava T; Tsoukas MA; Morais JA; Santosa S; 37194560
PERFORM
5 Association between rs174537 FADS1 polymorphism and immune cell profiles in abdominal and femoral subcutaneous adipose tissue: an exploratory study in adults with obesity Wang C; Murphy J; Delaney KZ; Khor N; Morais JA; Tsoukas MA; Lowry DE; Mutch DM; Santosa S; 33595419
PERFORM
6 Sex Affects Regional Variations in Subcutaneous Adipose Tissue T Cells but not Macrophages in Adults with Obesity Murphy J; Delaney KZ; Dam V; Tam BT; Khor N; Tsoukas MA; Morais JA; Santosa S; 33179451
PERFORM
7 The Association Between Dietary Pattern Adherence, Cognitive Stimulating Lifestyle, and Cognitive Function Among Older Adults From the Quebec Longitudinal Study on Nutrition and Successful Aging Parrott MD; Carmichael PH; Laurin D; Greenwood CE; Anderson ND; Ferland G; Gaudreau P; Belleville S; Morais JA; Kergoat MJ; Fiocco AJ; 33063101
PERFORM
8 A reliable, reproducible flow cytometry protocol for immune cell quantification in human adipose tissue. Delaney KZ, Dam V, Murphy J, Morais JA, Denis R, Atlas H, Pescarus R, Garneau PY, Santosa S 32926866
PERFORM
9 Acetyl-CoA regulation, OXPHOS integrity and leptin level are different in females with different onsets of obesity. Tam BT, Murphy J, Khor N, Morais JA, Santosa S 32808657
PERFORM
10 Sex differences in the relationship between dietary pattern adherence and cognitive function among older adults: findings from the NuAge study. D'Amico D, Parrott MD, Greenwood CE, Ferland G, Gaudreau P, Belleville S, Laurin D, Anderson ND, Kergoat MJ, Morais JA, Presse N, Fiocco AJ, 32563260
PERFORM
11 Obesity and ageing: Two sides of the same coin. Tam BT, Morais JA, Santosa S 32020741
PERFORM
12 Guidelines for Gait Assessments in the Canadian Consortium on Neurodegeneration in Aging (CCNA). Cullen S, Montero-Odasso M, Bherer L, Almeida Q, Fraser S, Muir-Hunter S, Li K, Liu-Ambrose T, McGibbon CA, McIlroy W, Middleton LE, Sarquis-Adamson Y, Beauchet O, McFadyen BJ, Morais JA, Camicioli R, Canadian Gait and Cognition Network 29977431
ENCS
13 SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment. Montero-Odasso M, Almeida QJ, Burhan AM, Camicioli R, Doyon J, Fraser S, Li K, Liu-Ambrose T, Middleton L, Muir-Hunter S, McIlroy W, Morais JA, Pieruccini-Faria F, Shoemaker K, Speechley M, Vasudev A, Zou GY, Berryman N, Lussier M, Vanderhaeghe L, Bherer L 29661156
PERFORM
14 Consensus on Shared Measures of Mobility and Cognition: From the Canadian Consortium on Neurodegeneration in Aging (CCNA). Montero-Odasso M, Almeida QJ, Bherer L, Burhan AM, Camicioli R, Doyon J, Fraser S, Muir-Hunter S, Li KZH, Liu-Ambrose T, McIlroy W, Middleton L, Morais JA, Sakurai R, Speechley M, Vasudev A, Beauchet O, Hausdorff JM, Rosano C, Studenski S, Verghese J, Canadian Gait and Cognition Network 30101279
PERFORM
15 Use of routinely available clinical, nutritional, and functional criteria to classify cachexia in advanced cancer patients. Vigano AAL, Morais JA, Ciutto L, Rosenthall L, di Tomasso J, Khan S, Olders H, Borod M, Kilgour RD 27793524
HKAP
16 Intra-Abdominal Adipose Tissue Quantification by Alternative Versus Reference Methods: A Systematic Review and Meta-Analysis. Murphy J, Bacon SL, Morais JA, Tsoukas MA, Santosa S 31131996
PERFORM

 

Title:Consensus on Shared Measures of Mobility and Cognition: From the Canadian Consortium on Neurodegeneration in Aging (CCNA).
Authors:Montero-Odasso MAlmeida QJBherer LBurhan AMCamicioli RDoyon JFraser SMuir-Hunter SLi KZHLiu-Ambrose TMcIlroy WMiddleton LMorais JASakurai RSpeechley MVasudev ABeauchet OHausdorff JMRosano CStudenski SVerghese JCanadian Gait and Cognition Network
Link:https://www.ncbi.nlm.nih.gov/pubmed/30101279?dopt=Abstract
DOI:10.1093/gerona/gly148
Publication:The journals of gerontology. Series A, Biological sciences and medical sciences
Keywords:AgingCognitionConsensusFallsGaitMobilityNeurodegenerative diseases
PMID:30101279 Category:J Gerontol A Biol Sci Med Sci Date Added:2019-06-04
Dept Affiliation: PERFORM
1 Department of Medicine, Division of Geriatric Medicine, University of Western Ontario, London, Canada.
2 Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada.
3 Gait and Brain Lab, Parkwood Institute, Lawson Health Research Institute, London, Ontario, Canada.
4 Department of Kinesiology and Physical Education, Sun Life Financial Movement Disorders Research Centre, Wilfrid Laurier University, Waterloo, Ontario, Canada.
5 Department of Psychology and PERFORM Centre, Concordia University, Montréal, Quebec, Canada.
6 Centre de Recherche, Institut Universitaire de Gériatrie de Montréal, Quebec, Canada.
7 Department of Medicine, University of Montreal, Quebec, Canada.
8 Montreal Heart Institute, Research Centre, Quebec, Canada.
9 Department of Psychiatry, Geriatric Psychiatry, Schulich School of Medicine, University of Western Ontario, London, Canada.
10 Lawson Health Research Institute, London, Ontario, Canada.
11 Department of Medicine, Geriatric and Cognitive Neurology, University of Alberta, Edmonton, Canada.
12 Functional Neuroimaging Unit, University of Montreal, Quebec, Canada.
13 Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ontario, Canada.
14 Faculty of Health Sciences, School of Physical Therapy, University of Western Ontario, London, Canada.
15 Department of Physical Therapy, Centre for Hip Health and Mobility, University of British Columbia, Canada.
16 Djavad Mowafaghian Centre for Brain Health, Vancouver Coastal Research Institute, University of British Columbia, Canada.
17 Division of Neurology and Department of Medicine, University of Toronto, Ontario, Canada.
18 Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Ontario, Canada.
19 Department of Kinesiology, University of Waterloo, Ontario, Canada.
20 Department of Medicine, Division of Geriatrics and Centre of Excellence in Aging and Chronic Disease, McGill University, Montréal, Quebec, Canada.
21 Department of Medicine, Division of Clinical Pharmacology, University of Western Ontario, London, Canada.
22 Department of Medicine, Division of Geriatric Medicine, McGill University, Montréal, Quebec, Canada.
23 Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Quebec, Canada.
24 RUIS McGill Centre of Excellence on Aging and Chronic Disease - CEViMaC, Montréal, Quebec, Canada.
25 Center for the Study of Movement, Cognition and Mobility, Neurological Institute, Tel Aviv Sourasky Medical Center, Israel.
26 Department of Physical Therapy, Sackler Faculty of Medicine, and Sagol School of Neuroscience, Tel Aviv University, Israel.
27 Rush Alzheimer's Disease Center and Department of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.
28 Department of Epidemiology, University of Pittsburgh, Pennsylvania.
29 Division of Geriatric Medicine, School of Medicine, University of Pittsburgh, Pennsylvania.
30 Department of Medicine, Albert Einstein College of Medicine, Bronx, New York.

Description:

Consensus on Shared Measures of Mobility and Cognition: From the Canadian Consortium on Neurodegeneration in Aging (CCNA).

J Gerontol A Biol Sci Med Sci. 2019 May 16;74(6):897-909

Authors: Montero-Odasso M, Almeida QJ, Bherer L, Burhan AM, Camicioli R, Doyon J, Fraser S, Muir-Hunter S, Li KZH, Liu-Ambrose T, McIlroy W, Middleton L, Morais JA, Sakurai R, Speechley M, Vasudev A, Beauchet O, Hausdorff JM, Rosano C, Studenski S, Verghese J, Canadian Gait and Cognition Network

Abstract

BACKGROUND: A new paradigm is emerging in which mobility and cognitive impairments, previously studied, diagnosed, and managed separately in older adults, are in fact regulated by shared brain resources. Deterioration in these shared brain mechanisms by normal aging and neurodegeneration increases the risk of developing dementia, falls, and fractures. This new paradigm requires an integrated approach to measuring both domains. We aim to identify a complementary battery of existing tests of mobility and cognition in community-dwelling older adults that enable assessment of motor-cognitive interactions.

METHODS: Experts on mobility and cognition in aging participated in a semistructured consensus based on the Delphi process. After performing a scoping review to select candidate tests, multiple rounds of consultations provided structured feedback on tests that captured shared characteristics of mobility and cognition. These tests needed to be sensitive to changes in both mobility and cognition, applicable across research studies and clinics, sensitive to interventions, feasible to perform in older adults, been previously validated, and have minimal ceiling/floor effects.

RESULTS: From 17 tests appraised, 10 tests fulfilled prespecified criteria and were selected as part of the "Core-battery" of tests. The expert panel also recommended a "Minimum-battery" of tests that included gait speed, dual-task gait speed, the Montreal Cognitive Assessment and Trail Making Test A&B.

CONCLUSIONS: A standardized assessment battery that captures shared characteristics of mobility and cognition seen in aging and neurodegeneration may increase comparability across research studies, detection of subtle or common reversible factors, and accelerate research progress in dementia, falls, and aging-related disabilities.

PMID: 30101279 [PubMed - in process]





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