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PubMed Publications| Keyword search (4,164 papers available) |  |
"Morais JA" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | The age of obesity onset affects changes in subcutaneous adipose tissue macrophages and T cells after weight loss | Murphy J; Morais JA; Tsoukas MA; Cooke AB; Daskalopoulou SS; Santosa S; | 40831565 SOH |
| 2 | Intramyocellular lipid use is altered with exercise in males with childhood-onset obesity despite no differences in substrate oxidation | Feola S; Al-Nabelsi L; Tam BT; Near J; Morais JA; Santosa S; | 39875595 HKAP |
| 3 | Age of obesity onset affects subcutaneous adipose tissue cellularity differently in the abdominal and femoral region | Murphy J; Dera A; Morais JA; Tsoukas MA; Khor N; Sazonova T; Almeida LG; Cooke AB; Daskalopoulou SS; Tam BT; Santosa S; | 39045668 SOH |
| 4 | Senescence markers in subcutaneous preadipocytes differ in childhood- versus adult-onset obesity before and after weight loss | Murphy J; Tam BT; Kirkland JL; Tchkonia T; Giorgadze N; Pirtskhalava T; Tsoukas MA; Morais JA; Santosa S; | 37194560 PERFORM |
| 5 | Association between rs174537 FADS1 polymorphism and immune cell profiles in abdominal and femoral subcutaneous adipose tissue: an exploratory study in adults with obesity | Wang C; Murphy J; Delaney KZ; Khor N; Morais JA; Tsoukas MA; Lowry DE; Mutch DM; Santosa S; | 33595419 PERFORM |
| 6 | Sex Affects Regional Variations in Subcutaneous Adipose Tissue T Cells but not Macrophages in Adults with Obesity | Murphy J; Delaney KZ; Dam V; Tam BT; Khor N; Tsoukas MA; Morais JA; Santosa S; | 33179451 PERFORM |
| 7 | The Association Between Dietary Pattern Adherence, Cognitive Stimulating Lifestyle, and Cognitive Function Among Older Adults From the Quebec Longitudinal Study on Nutrition and Successful Aging | Parrott MD; Carmichael PH; Laurin D; Greenwood CE; Anderson ND; Ferland G; Gaudreau P; Belleville S; Morais JA; Kergoat MJ; Fiocco AJ; | 33063101 PERFORM |
| 8 | A reliable, reproducible flow cytometry protocol for immune cell quantification in human adipose tissue. | Delaney KZ, Dam V, Murphy J, Morais JA, Denis R, Atlas H, Pescarus R, Garneau PY, Santosa S | 32926866 PERFORM |
| 9 | Acetyl-CoA regulation, OXPHOS integrity and leptin level are different in females with different onsets of obesity. | Tam BT, Murphy J, Khor N, Morais JA, Santosa S | 32808657 PERFORM |
| 10 | Sex differences in the relationship between dietary pattern adherence and cognitive function among older adults: findings from the NuAge study. | D'Amico D, Parrott MD, Greenwood CE, Ferland G, Gaudreau P, Belleville S, Laurin D, Anderson ND, Kergoat MJ, Morais JA, Presse N, Fiocco AJ, | 32563260 PERFORM |
| 11 | Obesity and ageing: Two sides of the same coin. | Tam BT, Morais JA, Santosa S | 32020741 PERFORM |
| 12 | Guidelines for Gait Assessments in the Canadian Consortium on Neurodegeneration in Aging (CCNA). | Cullen S, Montero-Odasso M, Bherer L, Almeida Q, Fraser S, Muir-Hunter S, Li K, Liu-Ambrose T, McGibbon CA, McIlroy W, Middleton LE, Sarquis-Adamson Y, Beauchet O, McFadyen BJ, Morais JA, Camicioli R, Canadian Gait and Cognition Network | 29977431 ENCS |
| 13 | SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment. | Montero-Odasso M, Almeida QJ, Burhan AM, Camicioli R, Doyon J, Fraser S, Li K, Liu-Ambrose T, Middleton L, Muir-Hunter S, McIlroy W, Morais JA, Pieruccini-Faria F, Shoemaker K, Speechley M, Vasudev A, Zou GY, Berryman N, Lussier M, Vanderhaeghe L, Bherer L | 29661156 PERFORM |
| 14 | Consensus on Shared Measures of Mobility and Cognition: From the Canadian Consortium on Neurodegeneration in Aging (CCNA). | Montero-Odasso M, Almeida QJ, Bherer L, Burhan AM, Camicioli R, Doyon J, Fraser S, Muir-Hunter S, Li KZH, Liu-Ambrose T, McIlroy W, Middleton L, Morais JA, Sakurai R, Speechley M, Vasudev A, Beauchet O, Hausdorff JM, Rosano C, Studenski S, Verghese J, Canadian Gait and Cognition Network | 30101279 PERFORM |
| 15 | Use of routinely available clinical, nutritional, and functional criteria to classify cachexia in advanced cancer patients. | Vigano AAL, Morais JA, Ciutto L, Rosenthall L, di Tomasso J, Khan S, Olders H, Borod M, Kilgour RD | 27793524 HKAP |
| 16 | Intra-Abdominal Adipose Tissue Quantification by Alternative Versus Reference Methods: A Systematic Review and Meta-Analysis. | Murphy J, Bacon SL, Morais JA, Tsoukas MA, Santosa S | 31131996 PERFORM |
| Title: | Sex Affects Regional Variations in Subcutaneous Adipose Tissue T Cells but not Macrophages in Adults with Obesity | ||||
| Authors: | Murphy J, Delaney KZ, Dam V, Tam BT, Khor N, Tsoukas MA, Morais JA, Santosa S | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/33179451/ | ||||
| DOI: | 10.1002/oby.23039 | ||||
| Publication: | Obesity (Silver Spring, Md.) | ||||
| Keywords: | |||||
| PMID: | 33179451 | Category: | Date Added: | 2020-11-12 | |
| Dept Affiliation: |
PERFORM
1 Department of Health, Kinesiology, and Applied Physiology, Concordia University, Montreal, Quebec, Canada. 2 Metabolism, Obesity, and Nutrition Laboratory, PERFORM Centre, Concordia University, Montreal, Quebec, Canada. 3 Centre de recherche - Axe maladies chroniques, Centre intégré universitaire de santé et de services sociaux du Nord-de-l'Ile-de-Montréal, Hôpital du Sacré-Coeur de Montréal, Montreal, Quebec, Canada. 4 Division of Endocrinology, Department of Medicine, McGill University, Royal Victoria Hospital, MUHC Glen site, Montreal, Quebec, Canada. 5 Division of Geriatric Medicine, Department of Medicine, McGill University, MUHC-Montreal General Hospital, Montreal, Quebec, Canada. |
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Description: |
Objective: The inflammatory environment in lower-body subcutaneous adipose tissue (SAT) has been largely unexplored. This study aimed to examine the effects of region (upper body vs. lower body) and sex on SAT immune cell profiles in young adults with obesity. Methods: Abdominal (AB) and femoral (FEM) SAT was collected from 12 males (mean [SEM] age = 30.8 [1.4] years; mean [SEM] BMI = 34.1 [1.1] kg/m2 ) and 22 females (mean [SEM] age = 30.6 [0.6] years; mean [SEM] BMI = 34.0 [0.7] kg/m2 ) with obesity via needle aspiration. Flow cytometry was used to quantify macrophage (CD68+) and T-cell (CD3+) subpopulations in the stromovascular fraction of each SAT region. Results: Females had a greater proportion of most T-cell types (CD3+CD4+CD45RA+, CD3+CD4+CD45RA-, and CD3+CD8+CD45RA+) in FEM compared with AB SAT, while males had similar proportions in both regions. Regardless of sex, the M1-like macrophage population (CD68+CD206-) was proportionally higher in AB SAT than in FEM SAT. Conclusions: Results showed that T-cell populations vary by SAT region in females but not males. Both sexes, however, have proportionately more proinflammatory macrophages in upper-body than in lower-body SAT. It remains to be seen how these unique immune cell profiles in males and females with obesity contribute to adipose tissue inflammation and metabolic disease risk. |
