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PubMed Publications| Keyword search (4,164 papers available) |  |
"Li W" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Obstructive Sleep Apnea Risk and Mental Health Conditions Among Older Canadian Adults in the Canadian Longitudinal Study on Aging | Kendzerska T; Mallick R; Li W; Robillard R; Taler V; Webber C; Saymeh M; Dang-Vu TT; Tanuseputro P; Fiedorowicz JG; | 41632160 HKAP |
| 2 | Solid solvation structure design improves all-solid-state organic batteries | Hu Y; Su H; Fu J; Luo J; Yu Q; Zhao F; Li W; Deng S; Liu Y; Yuan Y; Gan Y; Wang Y; Kim JT; Chen N; Shakouri M; Hao X; Gao Y; Pang T; Zhang N; Jiang M; Li X; Zhao Y; Tu J; Wang C; Sun X; | 40759737 ENCS |
| 3 | Impairing the interaction between Erg11 and cytochrome P450 reductase Ncp1 enhances azoles antifungal activities | Li W; Whiteway M; Hang S; Yu J; Lu H; Jiang Y; | 40707518 BIOLOGY |
| 4 | Pitavastatin Calcium Confers Fungicidal Properties to Fluconazole by Inhibiting Ubiquinone Biosynthesis and Generating Reactive Oxygen Species | Li W; Feng Y; Feng Z; Wang L; Whiteway M; Lu H; Jiang Y; | 38929106 BIOLOGY |
| 5 | A Small Molecule Inhibitor of Erg251 Makes Fluconazole Fungicidal by Inhibiting the Synthesis of the 14α-Methylsterols | Lu H; Li W; Whiteway M; Wang H; Zhu S; Ji Z; Feng Y; Yan L; Fang T; Li L; Ni T; Zhang X; Lv Q; Ding Z; Qiu L; Zhang D; Jiang Y; | 36475771 BIOLOGY |
| 6 | Uncovering global-scale risks from commercial chemicals in air | Liu Q; Li L; Zhang X; Saini A; Li W; Hung H; Hao C; Li K; Lee P; Wentzell JJB; Huo C; Li SM; Harner T; Liggio J; | 34912090 CHEMBIOCHEM |
| 7 | Calcium-calcineurin signaling pathway in Candida albicans: A potential drug target | Li W; Shrivastava M; Lu H; Jiang Y; | 33989979 BIOLOGY |
| 8 | Comprehensive evaluation of adsorption performances of carbonaceous materials for sulfonamide antibiotics removal. | Luo B, Huang G, Yao Y, An C, Li W, Zheng R, Zhao K | 32886308 CONCORDIA |
| 9 | An international Delphi consensus study to define motivational communication in the context of developing a training program for physicians. | Dragomir AI, Boucher VG, Bacon SL, Gemme C, Szczepanik G, Corace K, Campbell TS, Vallis MT, Garber G, Rouleau C, Rabi D, Diodati JG, Ghali W, Lavoie KL | 32145022 HKAP |
| Title: | Calcium-calcineurin signaling pathway in Candida albicans: A potential drug target | ||||
| Authors: | Li W, Shrivastava M, Lu H, Jiang Y | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/33989979/ | ||||
| DOI: | 10.1016/j.micres.2021.126786 | ||||
| Publication: | Microbiological research | ||||
| Keywords: | Antifungal targets; Calcium-calcineurin signaling pathway; Candida albicans; | ||||
| PMID: | 33989979 | Category: | Date Added: | 2021-05-19 | |
| Dept Affiliation: |
BIOLOGY
1 Department of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China. 2 Department of Biology, Concordia University, Montreal, QC, Canada. 3 Department of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China. Electronic address: luhui2019@tongji.edu.cn. 4 Department of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China. Electronic address: jiangyy@tongji.edu.cn. |
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Description: |
Increased morbidity and mortality of candidiasis are a notable threat to the immunocompromised patients. At present, the types of drugs available to treat C. albicans infection are relatively limited. Moreover, the emergence of antifungal drug resistance of C. albicans makes the treatment of C. albicans infection more difficult. The calcium-calcineurin signaling pathway plays a crucial role in the survival and pathogenicity of C. albicans and may act as a potential target against C. albicans. In this review, we summarized functions of the calcium-calcineurin signaling pathway in several biological processes, compared the differences of this signaling pathway between C. albicans and humans, and described anti-C. albicans activity of inhibitors of this signaling pathway. We believe that targeting the calcium-calcineurin signaling pathway is a promising strategy to cope with C. albicans infection. |
