Keyword search (4,163 papers available)

"Helfield B" Authored Publications:

Title Authors PubMed ID
1 Thermal sonogenetics for adoptive cell transfer therapy Baez A; Hazel K; Guertin Z; Fong E; Manus MM; Kaloyannis A; Helfield B; 41748028
BIOLOGY
2 Shear Stress and Microbubble-Mediated Modulation of Endothelial Cell Immunobiology Memari E; Singh D; Alkins R; Helfield B; 40657183
PHYSICS
3 Deformable detection transformers for domain adaptable ultrasound localization microscopy with robustness to point spread function variations Gharamaleki SK; Helfield B; Rivaz H; 40640235
PHYSICS
4 Investigation of Phase-Change Droplets and Fast Imaging for Indicator Dilution Measurement of Flow Zajac Z; Helfield B; Williams R; Sheeran P; Tremblay-Darveau C; Yoo K; Burns PN; 40387284
BIOLOGY
5 Flow rate modulates focused ultrasound-mediated vascular delivery of microRNA He S; Singh D; Helfield B; 39850318
BIOLOGY
6 Focused Ultrasound and Microbubble-Mediated Delivery of CRISPR-Cas9 Ribonucleoprotein to Human Induced Pluripotent Stem Cells Hazel K; Singh D; He S; Guertin Z; Husser MC; Helfield B; 39797397
BIOLOGY
7 The effect of micro-vessel viscosity on the resonance response of a two-microbubble system Yusefi H; Helfield B; 39705920
BIOLOGY
8 Immunomodulation of human T cells by microbubble-mediated focused ultrasound Baez A; Singh D; He S; Hajiaghayi M; Gholizadeh F; Darlington PJ; Helfield B; 39502696
BIOLOGY
9 Shear stress preconditioning and microbubble flow pattern modulate ultrasound-assisted plasma membrane permeabilization Memari E; Helfield B; 38988819
BIOLOGY
10 Cardiac gene delivery using ultrasound: State of the field Singh D; Memari E; He S; Yusefi H; Helfield B; 38983873
BIOLOGY
11 Focused ultrasound-assisted delivery of immunomodulating agents in brain cancer Memari E; Khan D; Alkins R; Helfield B; 38266715
BIOLOGY
12 Subharmonic resonance of phospholipid coated ultrasound contrast agent microbubbles Yusefi H; Helfield B; 38217906
BIOLOGY
13 Cavitation-Enhanced Drug Delivery and Immunotherapy Helfield B; Sirsi S; Kwan J; Gray M; 37765176
PHYSICS
14 Fluid flow influences ultrasound-assisted endothelial membrane permeabilization and calcium flux Memari E; Hui F; Yusefi H; Helfield B; 37150403
PHYSICS
15 Stable Cavitation-Mediated Delivery of miR-126 to Endothelial Cells He S; Singh D; Yusefi H; Helfield B; 36559150
BIOLOGY
16 The influence of inter-bubble spacing on the resonance response of ultrasound contrast agent microbubbles Yusefi H; Helfield B; 36223708
BIOLOGY
17 An Overview of Cell Membrane Perforation and Resealing Mechanisms for Localized Drug Delivery He S; Singh D; Helfield B; 35456718
BIOLOGY
18 Lateral Position-Dependent Velocity Estimation Error in Plane-Wave Doppler Ultrasound Systems Wei L; Williams R; Loupas T; Helfield B; Burns PN; 34006440
IMAGING
19 Transendothelial Perforations and the Sphere of Influence of Single-Site Sonoporation. Helfield B, Chen X, Watkins SC, Villanueva FS 32402675
BIOLOGY

 

Title:Lateral Position-Dependent Velocity Estimation Error in Plane-Wave Doppler Ultrasound Systems
Authors:Wei LWilliams RLoupas THelfield BBurns PN
Link:https://pubmed.ncbi.nlm.nih.gov/34006440/
DOI:10.1016/j.ultrasmedbio.2021.03.023
Publication:Ultrasound in medicine & biology
Keywords:Aperture broadeningDoppler velocity estimationIntrinsic spectral broadeningPlane-wave ultrasound imagingVelocity error
PMID:34006440 Category: Date Added:2021-05-19
Dept Affiliation: IMAGING
1 Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Sunnybrook Research Institute, Toronto, Ontario, Canada.
2 Sunnybrook Research Institute, Toronto, Ontario, Canada.
3 Philips Ultrasound, Bothell, Washington, USA.
4 Concordia University, Montreal, Quebec, Canada.
5 Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Sunnybrook Research Institute, Toronto, Ontario, Canada. Electronic address: Petern.burns@utoronto.ca.

Description:

Doppler ultrasound has become a standard method used to diagnose and grade vascular diseases and monitor their progression. Conventional focused-beam color Doppler imaging is routinely used in clinical practice, but suffers from inherent trade-offs between spatial, temporal and velocity resolution. Newer, plane-wave Doppler imaging offers rapid simultaneous acquisition of B-mode, color and spectral Doppler information across large fields of view, making it a potentially useful method for quantitative estimation of blood flow velocities in the clinic. However, plane-wave imaging can lead to a substantial error in velocity estimation, which is dependent on the lateral location within the image. This is seen in both clinical and experimental plane-wave systems. In the work described in this article, we quantified this velocity error under different geometric and beamforming conditions using numerical simulation and experimental phantoms. We found that the lateral-dependent velocity errors are caused by asymmetrical geometric spectral broadening, and outline a correction algorithm that can mitigate these errors.





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