Keyword search (4,163 papers available)

"Grenier S" Authored Publications:

Title Authors PubMed ID
1 Effects of cognitive-behavioral therapy for insomnia during sedative-hypnotics withdrawal on sleep and cognition in older adults Barbaux L; Cross NE; Perrault AA; Es-Sounni M; Desrosiers C; Clerc D; Andriamampionona F; Lussier D; Tannenbaum C; Guimond A; Grenier S; Gouin JP; Dang-Vu TT; 41092866
SOH
2 Factors associated with change in moderate or severe symptoms of anxiety and depression in community-living adults and older adults during the COVID-19 pandemic Vasiliadis HM; Spagnolo J; Bartram M; Fleury MJ; Gouin JP; Grenier S; Roberge P; Shen-Tu G; Vena JE; Lamoureux-Lamarche C; Wang J; 38117417
PSYCHOLOGY
3 Factors associated with mental health service use during the pandemic: Initiation and barriers Vasiliadis HM; Spagnolo J; Fleury MJ; Gouin JP; Roberge P; Bartram M; Grenier S; Shen-Tu G; Vena JE; Wang J; 37646244
PSYCHOLOGY
4 Correlates and trajectories of loneliness among community-dwelling older adults during the COVID-19 pandemic: A Canadian longitudinal study Lara E; Matovic S; Vasiliadis HM; Grenier S; Berbiche D; de la Torre-Luque A; Gouin JP; 37499331
PSYCHOLOGY
5 Insomnia symptoms among older adults during the first year of the COVID-19 pandemic: A longitudinal study Gong K; Garneau J; Grenier S; Vasiliadis HM; Dang-Vu TT; Dialahy IZ; Gouin JP; 37380593
HKAP
6 Mental health service use and associated predisposing, enabling and need factors in community living adults and older adults across Canada Vasiliadis HM; Spagnolo J; Fleury MJ; Gouin JP; Roberge P; Bartram M; Grenier S; Shen-Tu G; Vena JE; Wang J; 37046270
PSYCHOLOGY
7 Trajectories of psychological distress during the COVID-19 pandemic among community-dwelling older adults in Quebec: A longitudinal study Matovic S; Grenier S; Jauvin F; Gravel C; Vasiliadis HM; Vasil N; Belleville S; Rainville P; Dang-Vu TT; Aubertin-Leheudre M; Knäuper B; Dialahy IZ; Gouin JP; 36703303
HKAP
8 Behavioral and Psychological Symptoms that Predict Cognitive Decline or Impairment in Cognitively Normal Middle-Aged or Older Adults: a Meta-Analysis. Hudon C, Escudier F, De Roy J, Croteau J, Cross N, Dang-Vu TT, Zomahoun HTV, Grenier S, Gagnon JF, Parent A, Bruneau MA, Belleville S, Consortium for the Early Identification of Alzheimer’s Disease Quebec 32394109
HKAP
9 Effects of Dance/Movement Training vs. Aerobic Exercise Training on cognition, physical fitness and quality of life in older adults: A randomized controlled trial. Esmail A, Vrinceanu T, Lussier M, Predovan D, Berryman N, Houle J, Karelis A, Grenier S, Minh Vu TT, Villalpando JM, Bherer L 31987547
PERFORM
10 The Association between Generalized Anxiety Disorder, Subthreshold Anxiety Symptoms and Fear of Falling among Older Adults: Preliminary Results from a Pilot Study. Payette MC, Bélanger C, Benyebdri F, Filiatrault J, Bherer L, Bertrand JA, Nadeau A, Bruneau MA, Clerc D, Saint-Martin M, Cruz-Santiago D, Ménard C, Nguyen P, Vu TTM, Comte F, Bobeuf F, Grenier S 28452660
PERFORM
11 Anti-Dementia Drugs, Gait Performance and Mental Imagery of Gait: A Non-Randomized Open-Label Trial. Beauchet O, Barden J, Liu-Ambrose T, Chester VL, Annweiler C, Szturm T, Grenier S, Léonard G, Bherer L, Allali G, Canadian Gait Consortium 27568453
PERFORM
12 Association Between Falls and Brain Subvolumes: Results from a Cross-Sectional Analysis in Healthy Older Adults. Beauchet O, Launay CP, Barden J, Liu-Ambrose T, Chester VL, Szturm T, Grenier S, Léonard G, Bherer L, Annweiler C, Helbostad JL, Verghese J, Allali G, Biomathics and Canadian Gait Consortium 27785698
PERFORM

 

Title:Anti-Dementia Drugs, Gait Performance and Mental Imagery of Gait: A Non-Randomized Open-Label Trial.
Authors:Beauchet OBarden JLiu-Ambrose TChester VLAnnweiler CSzturm TGrenier SLéonard GBherer LAllali GCanadian Gait Consortium
Link:https://www.ncbi.nlm.nih.gov/pubmed/27568453?dopt=Abstract
DOI:10.1007/s40266-016-0391-0
Publication:Drugs & aging
Keywords:
PMID:27568453 Category:Drugs Aging Date Added:2019-04-15
Dept Affiliation: PERFORM
1 Department of Medicine, Division of Geriatric Medicine, Sir Mortimer B. Davis-Jewish General Hospital and Lady Davis Institute for Medical Research, McGill University, 3755 chemin de la Côte-Sainte-Catherine, Montréal, QC, H3T 1E2, Canada. olivier.beauchet@mcgill.ca.
2 Faculty of Medicine, McGill University, Montreal, QC, Canada. olivier.beauchet@mcgill.ca.
3 Centre of Excellence on Aging and Chronic Diseases of McGill Integrated University Health Network, Montreal, QC, Canada. olivier.beauchet@mcgill.ca.
4 Faculty of Kinesiology and Health Studies, Neuromechanical Research Centre, University of Regina, Regina, SK, Canada.
5 Aging, Mobility and Cognitive Neuroscience Laboratory, University of British Columbia, Vancouver, BC, Canada.
6 Andrew and Marjorie McCain Human Performance Laboratory, Faculty of Kinesiology, Richard J. Currie Center, University of New Brunswick, Fredericton, NB, Canada.
7 Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital, Angers, France.
8 University Memory Clinic of Angers, Angers, France.
9 UPRES EA 4638, University of Angers, UNAM, Angers, France.
10 Department of Medical Biophysics, Center for Functional and Metabolic Mapping, Schulich School of Medicine and Dentistry, Robarts Research Institute, University of Western Ontario, London, ON, Canada.
11 Department of Physical Therapy, College of Rehabilitation Sciences, University of Manitoba, Winnipeg, MB, Canada.
12 Centre de recherche, Institut universitaire de gériatrie de Montréal (CRIUGM), Montréal, QC, Canada.
13 Institut universitaire de gériatrie de Sherbrooke (IUGS), Montréal, QC, Canada.
14 PERFORM Centre and Department of Psychology, Concordia University, Montreal, QC, Canada.
15 Department of Neurology, Geneva University Hospital and University of Geneva, Geneva, Switzerland.

Description:

Anti-Dementia Drugs, Gait Performance and Mental Imagery of Gait: A Non-Randomized Open-Label Trial.

Drugs Aging. 2016 09;33(9):665-73

Authors: Beauchet O, Barden J, Liu-Ambrose T, Chester VL, Annweiler C, Szturm T, Grenier S, Léonard G, Bherer L, Allali G, Canadian Gait Consortium

Abstract

BACKGROUND: Few studies have examined the effect of anti-dementia drugs (i.e., acetylcholinesterase inhibitors and N-methyl-D-aspartate receptor antagonists) on gait performance. Past studies have focused on the stride time (i.e., gait cycle duration) but not on the mental imagery of gait.

OBJECTIVES: To compare mental imagery of gait and spatiotemporal gait parameters in patients with dementia [i.e., Alzheimer's disease (AD) and non-AD] before and after the use of anti-dementia drugs (i.e., acetylcholinesterase inhibitors and memantine) and in controls (i.e., patients with dementia who did not take anti-dementia drugs).

METHODS: A total of 112 patients (mean age 82.5 ± 4.2 years, 68.8 % female) with mild-to-moderate AD and non-AD dementia were included in this non-randomized open-label trial (n = 56 in the Intervention group, and n = 56 in the Control group matched for age, sex, and stage and type of dementia) nested in a cohort study (mean follow-up 238.5 ± 79.8 days). Mental imagery of gait was assessed with the actual and imagined Timed Up and Go tests (aTUG and iTUG) and the difference between aTUG and iTUG (i.e., delta-TUG). Spatiotemporal gait parameters were measured with the GAITRite(®) system during normal walking.

RESULTS: Participants in the Intervention group had a longer iTUG time (p < 0.001) and a lower delta-TUG value (p = 0.001) at the follow-up compared with those in the Control group. There was a significant increase in iTUG (p = 0.001) and decrease in delta-TUG (p < 0.001) from baseline to the follow-up only in the Intervention group. Multiple linear regression showed that the use of anti-dementia drugs was associated with a longer iTUG time and a lower delta-TUG value (best performance, p < 0.002).

CONCLUSIONS: Our findings showed an improvement in mental imagery of gait with the use of anti-dementia drugs, but no changes in actual gait performance.

TRIAL REGISTRATION: NCT01315704.

PMID: 27568453 [PubMed - indexed for MEDLINE]





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