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PubMed Publications| Keyword search (4,164 papers available) |  |
"Grenier S" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Effects of cognitive-behavioral therapy for insomnia during sedative-hypnotics withdrawal on sleep and cognition in older adults | Barbaux L; Cross NE; Perrault AA; Es-Sounni M; Desrosiers C; Clerc D; Andriamampionona F; Lussier D; Tannenbaum C; Guimond A; Grenier S; Gouin JP; Dang-Vu TT; | 41092866 SOH |
| 2 | Factors associated with change in moderate or severe symptoms of anxiety and depression in community-living adults and older adults during the COVID-19 pandemic | Vasiliadis HM; Spagnolo J; Bartram M; Fleury MJ; Gouin JP; Grenier S; Roberge P; Shen-Tu G; Vena JE; Lamoureux-Lamarche C; Wang J; | 38117417 PSYCHOLOGY |
| 3 | Factors associated with mental health service use during the pandemic: Initiation and barriers | Vasiliadis HM; Spagnolo J; Fleury MJ; Gouin JP; Roberge P; Bartram M; Grenier S; Shen-Tu G; Vena JE; Wang J; | 37646244 PSYCHOLOGY |
| 4 | Correlates and trajectories of loneliness among community-dwelling older adults during the COVID-19 pandemic: A Canadian longitudinal study | Lara E; Matovic S; Vasiliadis HM; Grenier S; Berbiche D; de la Torre-Luque A; Gouin JP; | 37499331 PSYCHOLOGY |
| 5 | Insomnia symptoms among older adults during the first year of the COVID-19 pandemic: A longitudinal study | Gong K; Garneau J; Grenier S; Vasiliadis HM; Dang-Vu TT; Dialahy IZ; Gouin JP; | 37380593 HKAP |
| 6 | Mental health service use and associated predisposing, enabling and need factors in community living adults and older adults across Canada | Vasiliadis HM; Spagnolo J; Fleury MJ; Gouin JP; Roberge P; Bartram M; Grenier S; Shen-Tu G; Vena JE; Wang J; | 37046270 PSYCHOLOGY |
| 7 | Trajectories of psychological distress during the COVID-19 pandemic among community-dwelling older adults in Quebec: A longitudinal study | Matovic S; Grenier S; Jauvin F; Gravel C; Vasiliadis HM; Vasil N; Belleville S; Rainville P; Dang-Vu TT; Aubertin-Leheudre M; Knäuper B; Dialahy IZ; Gouin JP; | 36703303 HKAP |
| 8 | Behavioral and Psychological Symptoms that Predict Cognitive Decline or Impairment in Cognitively Normal Middle-Aged or Older Adults: a Meta-Analysis. | Hudon C, Escudier F, De Roy J, Croteau J, Cross N, Dang-Vu TT, Zomahoun HTV, Grenier S, Gagnon JF, Parent A, Bruneau MA, Belleville S, Consortium for the Early Identification of Alzheimer’s Disease – Quebec | 32394109 HKAP |
| 9 | Effects of Dance/Movement Training vs. Aerobic Exercise Training on cognition, physical fitness and quality of life in older adults: A randomized controlled trial. | Esmail A, Vrinceanu T, Lussier M, Predovan D, Berryman N, Houle J, Karelis A, Grenier S, Minh Vu TT, Villalpando JM, Bherer L | 31987547 PERFORM |
| 10 | The Association between Generalized Anxiety Disorder, Subthreshold Anxiety Symptoms and Fear of Falling among Older Adults: Preliminary Results from a Pilot Study. | Payette MC, Bélanger C, Benyebdri F, Filiatrault J, Bherer L, Bertrand JA, Nadeau A, Bruneau MA, Clerc D, Saint-Martin M, Cruz-Santiago D, Ménard C, Nguyen P, Vu TTM, Comte F, Bobeuf F, Grenier S | 28452660 PERFORM |
| 11 | Anti-Dementia Drugs, Gait Performance and Mental Imagery of Gait: A Non-Randomized Open-Label Trial. | Beauchet O, Barden J, Liu-Ambrose T, Chester VL, Annweiler C, Szturm T, Grenier S, Léonard G, Bherer L, Allali G, Canadian Gait Consortium | 27568453 PERFORM |
| 12 | Association Between Falls and Brain Subvolumes: Results from a Cross-Sectional Analysis in Healthy Older Adults. | Beauchet O, Launay CP, Barden J, Liu-Ambrose T, Chester VL, Szturm T, Grenier S, Léonard G, Bherer L, Annweiler C, Helbostad JL, Verghese J, Allali G, Biomathics and Canadian Gait Consortium | 27785698 PERFORM |
| Title: | Effects of cognitive-behavioral therapy for insomnia during sedative-hypnotics withdrawal on sleep and cognition in older adults | ||||
| Authors: | Barbaux L, Cross NE, Perrault AA, Es-Sounni M, Desrosiers C, Clerc D, Andriamampionona F, Lussier D, Tannenbaum C, Guimond A, Grenier S, Gouin JP, Dang-Vu TT | ||||
| Link: | pubmed.ncbi.nlm.nih.gov/41092866/ | ||||
| DOI: | 10.1016/j.sleep.2025.106826 | ||||
| Publication: | Sleep medicine | ||||
| Keywords: | Ageing; CBTi; Cognition; Sedative-hypnotics withdrawal; Spindle; Subjective sleep; | ||||
| PMID: | 41092866 | Category: | Date Added: | 2025-10-16 | |
| Dept Affiliation: |
SOH
1 Sleep, Cognition and Neuroimaging Lab, Department of Health, Kinesiology and Applied Physiology, School of Health & Center for Studies in Behavioural Neurobiology, Concordia University, Montreal, Quebec, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada. Electronic address: loicbrb@gmail.com.2 Sleep, Cognition and Neuroimaging Lab, Department of Health, Kinesiology and Applied Physiology, School of Health & Center for Studies in Behavioural Neurobiology, Concordia University, Montreal, Quebec, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada; School of Psychology, University of Sydney, NSW, Australia.3 Sleep, Cognition and Neuroimaging Lab, Department of Health, Kinesiology and Applied Physiology, School of Health & Center for Studies in Behavioural Neurobiology, Concordia University, Montreal, Quebec, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada; Sleep and Circadian Group, Woolcock Institute of Medical Research and Macquarie University, Sydney, NSW, Australia.4 Sleep, Cognition and Neuroimaging Lab, Department of Health, Kinesiology and Applied Physiology, School of Health & Center for Studies in Behavioural Neurobiology, Concordia University, Montreal, Quebec, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada.5 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada.6 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada; Department of Psychology, University of Montreal, Quebec, Canada.7 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada; Stress, Interpersonal Relationship and Health Lab, Department of Psychology & Centre for Clinical Research in Health, Concordia University, Quebec, Canada.8 Sleep, Cognition and Neuroimaging Lab, Department of Health, Kinesiology and Applied Physiology, School of Health & Center for Studies in Behavioural Neurobiology, Concordia University, Montreal, Quebec, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada. Electronic address: tt.dangvu@concordia.ca. |
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Description: |
Objectives: Our objective was to assess the effect of cognitive-behavioral therapy for insomnia (CBTi) on subjective and objective sleep quality (including sleep spindles) and cognition during a sedative-hypnotics withdrawal program in older adults with insomnia disorder. Methods: We performed a two-arm randomized controlled trial (RCT) of a sedative-hypnotic withdrawal plan alone (WPo group) or combined with CBTi (WP + CBTi group) in 47 older adults with insomnia disorder over a sixteen-week period. Our primary outcomes were change in self-reported insomnia severity (Insomnia Severity Index (ISI)), sleep efficiency (SE) from sleep diaries, and change in SE and spindle density from polysomnographic (PSG) recordings collected at baseline and at post-intervention (16 weeks). Secondary outcomes included other sleep changes from PSG, actigraphy and sleep diaries, sleep and mood questionnaires and neuropsychological assessments (manual dexterity, attention/concentration, verbal inhibition, visuo-spatial abilities). Results: The withdrawal program was effective in achieving discontinuation and reducing insomnia severity, with similar success with and without CBTi. The combined intervention additionally improved subjective sleep quality and prevented the decrease in subjective sleep duration induced by sedative-hypnotic discontinuation. Neither intervention significantly impacted objective sleep architecture or cognitive performance. Furthermore, reduction in sleep spindle density was observed with combined CBTi and withdrawal, but not with withdrawal alone. Conclusions: Both withdrawal alone and sedative-hypnotic withdrawal combined with CBTi effectively facilitated discontinuation and reduced insomnia severity, with the combined intervention further enhancing subjective sleep quality and preserving sleep duration. Although neither approach significantly impacted objective sleep architecture or cognitive performance, the potential reduction in sleep spindle density linked to the combined intervention warrants further investigation. |
