Keyword search (4,163 papers available)

"Gauthier CJ" Authored Publications:

Title Authors PubMed ID
1 Cardiorespiratory fitness in relation to cerebral vascular and metabolic health in older adults with coronary artery disease Sanami S; Tremblay SA; Potvin-Jutras Z; Rezaei A; Sabra D; Gagnon C; Intzandt B; Mainville-Berthiaume A; Wright L; Gayda M; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ; 41680492
SOH
2 Greater cardiorespiratory fitness is associated with higher cerebral blood flow and lower oxygen extraction fraction in healthy older adults Sanami S; Rezaei A; Tremblay SA; Potvin-Jutras Z; Sabra D; Intzandt B; Gagnon C; Mainville-Berthiaume A; Wright L; Gayda M; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ; 41543005
SOH
3 Biomarkers Zhou J; Wearn A; Huck J; Hughes CS; Baracchini G; Sylvain E; Tremblay-Mercier J; Poirier J; Breitner JCSCS; Villeneuve S; Chakravarty MM; Tardif CL; Gauthier CJ; Daugherty AM; Turner GR; Spreng RN; 41499788
ENCS
4 The Impact of Coronary Artery Disease on Brain Vascular and Metabolic Health: Links to Cognitive Function Sanami S; Tremblay SA; Rezaei A; Potvin-Jutras Z; Sabra D; Intzandt B; Gagnon C; Mainville-Berthiaume A; Wright L; Gayda M; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ; 41452711
SOH
5 Alzheimer s Imaging Consortium Intzandt B; Potvin-Jutras Z; Whittingstall K; Gauthier CJ; 41433411
CONCORDIA
6 Public Health Intzandt B; Potvin-Jutras Z; Whittingstall K; Gauthier CJ; 41435069
CONCORDIA
7 Longitudinal effects of cerebrovascular reactivity and cerebral pulsatility in cognitively intact older adults with APOE4: links with cognition Potvin-Jutras Z; Tremblay PL; Mohammadi H; Villeneuve S; Spreng RN; Gauthier CJ; 41353310
SOH
8 The PREVENT-AD cohort: Accelerating Alzheimer s disease research and treatment in Canada and beyond Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Fajardo Valdez A; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Strikwerda-Brown C; Tardif CL; Gauthier CJ; Descoteaux M; Dadar M; Vachon-Presseau É; Baril AA; Ducharme S; Montembeault M; Geddes MR; Soucy JP; Rajah N; Laforce R; Bocti C; Davatzikos C; Bellec L; Rosa-Neto P; Baillet S; Evans AC; Collins DL; Chakravarty MM; Blennow K; Zetterbe 41020412
SOH
9 Multivariate white matter microstructure alterations in older adults with coronary artery disease Tremblay SA; Potvin-Jutras Z; Sabra D; Rezaei A; Sanami S; Gagnon C; Intzandt B; Mainville-Berthiaume A; Wright L; Leppert IR; Tardif CL; Steele CJ; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ; 40829939
SOH
10 The PREVENT-AD cohort: accelerating Alzheimer s disease research and treatment in Canada and beyond Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Valdez AF; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Strikwerda-Brown C; Tardif CL; Gauthier CJ; Descoteaux M; Dadar M; Vachon-Presseau É; Baril AA; Ducharme S; Montembeault M; Geddes MR; Soucy JP; Rajah N; Laforce R; Bocti C; Davatzikos C; Bellec L; Rosa-Neto P; Baillet S; Evans AC; Collins DL; Chakravarty MM; Blennow K; Zetterberg H; S 40778177
PSYCHOLOGY
11 Mapping cerebral blood perfusion and its links to multi-scale brain organization across the human lifespan Farahani A; Liu ZQ; Ceballos EG; Hansen JY; Wennberg K; Zeighami Y; Dadar M; Gauthier CJ; Dagher A; Misic B; 40729400
PHYSICS
12 Assessing quantitative MRI techniques using multimodal comparisons Carter F; Anwander A; Johnson M; Goucha T; Adamson H; Friederici AD; Lutti A; Gauthier CJ; Weiskopf N; Bazin PL; Steele CJ; 40705745
SOH
13 Variations in perfusion detectable in advance of microstructure in white matter aging Robinson TD; Sun YL; Chang PTH; Gauthier CJ; Chen JJ; 40694306
PHYSICS
14 Longitudinal relationships among cerebrospinal fluid biomarkers, cerebral blood flow, and grey matter volume in individuals with a familial history of Alzheimer s disease Sanami S; Intzandt B; Huck J; Villeneuve S; Iturria-Medina Y; Gauthier CJ; Prevent-Ad Research Group None; 40347524
CONCORDIA
15 Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer s disease Tremblay SA; Nathan Spreng R; Wearn A; Alasmar Z; Pirhadi A; Tardif CL; Chakravarty MM; Villeneuve S; Leppert IR; Carbonell F; Medina YI; Steele CJ; Gauthier CJ; 40086421
PSYCHOLOGY
16 Sex-specific effects of intensity and dose of physical activity on BOLD-fMRI cerebrovascular reactivity and cerebral pulsatility Potvin-Jutras Z; Intzandt B; Mohammadi H; Liu P; Chen JJ; Gauthier CJ; 40079560
SOH
17 Alzheimer's Imaging Consortium Tremblay SA; Spreng RN; Wearn A; Alasmar Z; Pirhadi A; Tardif CL; Chakravarty MM; Villeneuve S; Leppert IR; Carbonell F; Medina YI; Steele CJ; Gauthier CJ; 39782998
CONCORDIA
18 Biomarkers Tremblay SA; Spreng RN; Wearn A; Alasmar Z; Pirhadi A; Tardif CL; Chakravarty MM; Villeneuve S; Leppert IR; Carbonell F; Medina YI; Steele CJ; Gauthier CJ; 39785351
CONCORDIA
19 Sex-specific effects of intensity and dose of physical activity on BOLD-fMRI cerebrovascular reactivity and cerebral pulsatility Potvin-Jutras Z; Intzandt B; Mohammadi H; Liu P; Chen JJ; Gauthier CJ; 39416007
SOH
20 Neuromodulatory subcortical nucleus integrity is associated with white matter microstructure, tauopathy and APOE status Wearn A; Tremblay SA; Tardif CL; Leppert IR; Gauthier CJ; Baracchini G; Hughes C; Hewan P; Tremblay-Mercier J; Rosa-Neto P; Poirier J; Villeneuve S; Schmitz TW; Turner GR; Spreng RN; 38830849
SOH
21 MVComp toolbox: MultiVariate Comparisons of brain MRI features accounting for common information across metrics Tremblay SA; Alasmar Z; Pirhadi A; Carbonell F; Iturria-Medina Y; Gauthier CJ; Steele CJ; 38463982
SOH
22 Iron Deposition and Distribution Across the Hippocampus Is Associated with Pattern Separation and Pattern Completion in Older Adults at Risk for Alzheimer's Disease Zhou J; Wearn A; Huck J; Hughes C; Baracchini G; Tremblay-Mercier J; Poirier J; Villeneuve S; Tardif CL; Chakravarty MM; Daugherty AM; Gauthier CJ; Turner GR; Spreng RN; 38388425
PSYCHOLOGY
23 Decreased long-range temporal correlations in the resting-state functional magnetic resonance imaging blood-oxygen-level-dependent signal reflect motor sequence learning up to 2 weeks following training Jäger AP; Bailey A; Huntenburg JM; Tardif CL; Villringer A; Gauthier CJ; Nikulin V; Bazin PL; Steele CJ; 38124341
SOH
24 Modeling venous bias in resting state functional MRI metrics Huck J; Jäger AT; Schneider U; Grahl S; Fan AP; Tardif C; Villringer A; Bazin PL; Steele CJ; Gauthier CJ; 37498014
PERFORM
25 Cerebral blood flow in schizophrenia: A systematic review and meta-analysis of MRI-based studies Percie du Sert O; Unrau J; Gauthier CJ; Chakravarty M; Malla A; Lepage M; Raucher-Chéné D; 36341843
CRDH
26 Motor sequences; separating the sequence from the motor. A longitudinal rsfMRI study Jäger AP; Huntenburg JM; Tremblay SA; Schneider U; Grahl S; Huck J; Tardif CL; Villringer A; Gauthier CJ; Bazin PL; Steele CJ; 34704176
PERFORM
27 Sex moderations in the relationship between aortic stiffness, cognition, and cerebrovascular reactivity in healthy older adults Sabra D; Intzandt B; Desjardins-Crepeau L; Langeard A; Steele CJ; Frouin F; Hoge RD; Bherer L; Gauthier CJ; 34582484
PERFORM
28 Comparing the effect of Cognitive vs. Exercise Training on brain MRI outcomes in healthy older adults: A systematic review Intzandt B; Vrinceanu T; Huck J; Vincent T; Montero-Odasso M; Gauthier CJ; Bherer L; 34245760
PERFORM
29 White matter microstructural changes in short-term learning of a continuous visuomotor sequence Tremblay SA; Jäger AT; Huck J; Giacosa C; Beram S; Schneider U; Grahl S; Villringer A; Tardif CL; Bazin PL; Steele CJ; Gauthier CJ; 33885965
PERFORM
30 A Cross-Sectional Study on the Impact of Arterial Stiffness on the Corpus Callosum, a Key White Matter Tract Implicated in Alzheimer's Disease Badji A; de la Colina AN; Boshkovski T; Sabra D; Karakuzu A; Robitaille-Grou MC; Gros C; Joubert S; Bherer L; Lamarre-Cliche M; Stikov N; Gauthier CJ; Cohen-Adad J; Girouard H; 32741837
PERFORM
31 BOLD signal physiology: Models and applications. Gauthier CJ, Fan AP 29544818
IMAGING
32 High resolution atlas of the venous brain vasculature from 7 T quantitative susceptibility maps. Huck J, Wanner Y, Fan AP, Jäger AT, Grahl S, Schneider U, Villringer A, Steele CJ, Tardif CL, Bazin PL, Gauthier CJ 31278570
PSYCHOLOGY
33 Higher cardiovascular fitness level is associated with lower cerebrovascular reactivity and perfusion in healthy older adults. Intzandt B, Sabra D, Foster C, Desjardins-Crépeau L, Hoge RD, Steele CJ, Bherer L, Gauthier CJ 31342831
PERFORM
34 Advanced MRI techniques to improve our understanding of experience-induced neuroplasticity. Tardif CL, Gauthier CJ, Steele CJ, Bazin PL, Schäfer A, Schaefer A, Turner R, Villringer A 26318050
PERFORM
35 Elevated brain oxygen extraction fraction measured by MRI susceptibility relates to perfusion status in acute ischemic stroke. Fan AP, Khalil AA, Fiebach JB, Zaharchuk G, Villringer A, Villringer K, Gauthier CJ 30732551
PHYSICS
36 Arterial stiffness and brain integrity: A review of MRI findings. Badji A, Sabra D, Bherer L, Cohen-Adad J, Girouard H, Gauthier CJ 31063866
PERFORM
37 Higher levels of cardiovascular fitness are associated with better executive function and prefrontal oxygenation in younger and older women. Dupuy O, Gauthier CJ, Fraser SA, Desjardins-Crèpeau L, Desjardins M, Mekary S, Lesage F, Hoge RD, Pouliot P, Bherer L 25741267
PERFORM
38 Investigation of the confounding effects of vasculature and metabolism on computational anatomy studies. Tardif CL, Steele CJ, Lampe L, Bazin PL, Ragert P, Villringer A, Gauthier CJ 28159689
PERFORM
39 Age differences in brain signal variability are robust to multiple vascular controls. Garrett DD, Lindenberger U, Hoge RD, Gauthier CJ 28860455
PERFORM

 

Title:BOLD signal physiology: Models and applications.
Authors:Gauthier CJFan AP
Link:https://www.ncbi.nlm.nih.gov/pubmed/29544818?dopt=Abstract
DOI:10.1016/j.neuroimage.2018.03.018
Publication:NeuroImage
Keywords:
PMID:29544818 Category:Neuroimage Date Added:2019-08-07
Dept Affiliation: IMAGING
1 Concordia University, Montreal, Canada. Electronic address: claudine.gauthier@concordia.ca.
2 Stanford University, California, USA.

Description:

BOLD signal physiology: Models and applications.

Neuroimage. 2019 02 15;187:116-127

Authors: Gauthier CJ, Fan AP

Abstract

The BOLD contrast mechanism has a complex relationship with functional brain activity, oxygen metabolism, and neurovascular factors. Accurate interpretation of the BOLD signal for neuroscience and clinical applications necessitates a clear understanding of the sources of BOLD contrast and its relationship to underlying physiology. This review describes the physiological components that contribute to the BOLD signal and the steady-state calibrated BOLD models that enable quantification of functional changes with a separate challenge paradigm. The principles derived from these biophysical models are then used to interpret BOLD measurements in different neurological disorders in the presence of confounding vascular factors related to disease.

PMID: 29544818 [PubMed - indexed for MEDLINE]





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