Keyword search (4,163 papers available)

"Gamberi C" Authored Publications:

Title Authors PubMed ID
1 TANGO2 deficiency disease is predominantly caused by a lipid imbalance Sacher M; DeLoriea J; Mehranfar M; Casey C; Naaz A; Gamberi C; 38836374
BIOLOGY
2 Vitamin B5, a Coenzyme A precursor, rescues TANGO2 deficiency disease-associated defects in Drosophila and human cells Asadi P; Milev MP; Saint-Dic D; Gamberi C; Sacher M; 36502486
BIOLOGY
3 Empowering Melatonin Therapeutics with Drosophila Models Millet-Boureima C; Ennis CC; Jamison J; McSweeney S; Park A; Gamberi C; 34698120
BIOLOGY
4 Cyst Reduction by Melatonin in a Novel Drosophila Model of Polycystic Kidney Disease. Millet-Boureima C; Rozencwaig R; Polyak F; Gamberi C; 33238462
BIOLOGY
5 Drug discovery and chemical probing in Drosophila. Millet-Boureima C, Selber-Hnatiw S, Gamberi C 32551911
BIOLOGY
6 Editorial: RNA Regulation in Development and Disease. Chartrand P, Jaramillo M, Gamberi C 32411184
BIOLOGY
7 Cyst Reduction in a Polycystic Kidney Disease Drosophila Model Using Smac Mimics. Millet-Boureima C, Chingle R, Lubell WD, Gamberi C 31635379
BIOLOGY
8 Modeling Renal Disease "On the Fly". Millet-Boureima C, Porras Marroquin J, Gamberi C 29955604
BIOLOGY
9 Mapping the fly Malpighian tubule lipidome by imaging mass spectrometry Yang E; Gamberi C; Chaurand P; 31038251
BIOLOGY

 

Title:Modeling Renal Disease "On the Fly".
Authors:Millet-Boureima CPorras Marroquin JGamberi C
Link:https://www.ncbi.nlm.nih.gov/pubmed/29955604?dopt=Abstract
DOI:10.1155/2018/5697436
Publication:BioMed research international
Keywords:
PMID:29955604 Category:Biomed Res Int Date Added:2019-06-07
Dept Affiliation: BIOLOGY
1 Biology Department, Concordia University, Montreal, QC, Canada.

Description:

Modeling Renal Disease "On the Fly".

Biomed Res Int. 2018;2018:5697436

Authors: Millet-Boureima C, Porras Marroquin J, Gamberi C

Abstract

Detoxification is a fundamental function for all living organisms that need to excrete catabolites and toxins to maintain homeostasis. Kidneys are major organs of detoxification that maintain water and electrolyte balance to preserve physiological functions of vertebrates. In insects, the renal function is carried out by Malpighian tubules and nephrocytes. Due to differences in their circulation, the renal systems of mammalians and insects differ in their functional modalities, yet carry out similar biochemical and physiological functions and share extensive genetic and molecular similarities. Evolutionary conservation can be leveraged to model specific aspects of the complex mammalian kidney function in the genetic powerhouse Drosophila melanogaster to study how genes interact in diseased states. Here, we compare the human and Drosophila renal systems and present selected fly disease models.

PMID: 29955604 [PubMed - indexed for MEDLINE]





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