Keyword search (4,164 papers available)

"Chertkow H" Authored Publications:

Title Authors PubMed ID
1 Basic Science and Pathogenesis Borrie MJ; Phillips NA; Best S; Anastasiou-Ventura P; Aydogan T; Beaudoin C; Beuk J; Celotto I; Cole L; Das S; Fogarty J; Fouquet C; Gnassi L; Henri-Bellemare C; Pilon R; Sands J; Stirbu A; Truemner J; Chan S; Tucker A; Gajraj J; Bhangu J; Chertkow H; 41435411
CONCORDIA
2 Public Health Gurve D; Centen AP; Slack PJ; Dang-Vu TT; Belleville S; Anderson ND; Montero-Odasso M; Nygaard HB; Chertkow H; Feldman HH; Brewster PWH; Lim A; 41434309
PERFORM
3 Peripheral inflammation in a Canadian cohort of neurodegenerative conditions: Occurrence, determinants, and impact Seixas-Lima B; Rosa-Neto P; Phillips NA; Borrie M; Roncero CT; Lahiri D; Dori D; Eintracht S; Chertkow H; 41358624
PSYCHOLOGY
4 Use of lecanemab and donanemab in the Canadian healthcare system: Evidence, challenges, and areas for future research Smith EE; Phillips NA; Feldman HH; Borrie M; Ganesh A; Henri-Bhargava A; Desmarais P; Frank A; Badhwar A; Barlow L; Bartha R; Best S; Bethell J; Bhangu J; Black SE; Bocti C; Bronskill SE; Burhan AM; Calon F; Camicioli R; Campbell B; Collins DL; Dadar M; DeMarco ML; Ducharme S; Duchesne S; Einstein G; Fisk JD; Gawryluk JR; Grossman L; Ismail Z; Itzhak I; Joshi M; Harrison A; Kroger E; Kumar S; Laforce R; Lanctot KL; Lau M; Lee L; Masellis M; Massoud F; Mitchell SB; Montero-Odasso M; Myers Barnett K; Nygaard HB; Pasternak SH; Peters J; Rajah MN; Robillard JM; Rockwood K; Rosa-Neto P; Seitz DP; Soucy JP; Trenaman SC; Wellington CL; Zadem A; Chertkow H; 39893139
CONCORDIA
5 Basic Science and Pathogenesis Lima BS; Rosa-Neto P; Phillips N; Borrie M; Roncero CT; Lahiri D; Dori D; Chertkow H; 39751468
CONCORDIA
6 Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA) Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; Bélanger N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello C; Cynader M; Dang-Vu T; Das S; Dixon RA; Ducharme S; Einstein G; Evans AC; Fahnestock M; Feldman H; Ferland G; Finger E; Fisk JD; Fogarty J; Fon E; Gan-Or Z; Gauthier S; Greenwood C; Henri-Bellemare C; Herrmann N; Hogan DB; Hsiung R; Itzhak I; Jacklin K; Lanctôt K; Lim A; MacKenzie I; Masellis M; Maxwell C; McAiney C; McGilton K; McLaurin J; Mihailidis A; Mohades Z; Montero-Odasso M; Morgan D; Naglie G; Nygaard H; O' Connell M; Petersen R; Pilon R; Rajah MN; Rapoport M; Roach P; Robillard JM; Rogaeva E; Rosa-Neto P; Rylett J; Sadavoy J; St George-Hyslop P; Seitz D; Smith E; Stefanovic B; Vedel I; Walker JD; Wellington C; Whitehead V; Wittich W; 39636028
HKAP
7 A person with frontotemporal dementia shows increased metabolic rate across multiple brain regions after a series of tDCS sessions Roncero C; Nikelski J; Soucy JP; Lahiri D; Seixas-Lima B; Chertkow H; 37182684
PERFORM
8 Consensus Statement Regarding the Application of Biogen to Health Canada for Approval of Aducanumab Chertkow H; Rockwood K; Hogan DB; Phillips N; Montero-Odasso M; Amanullah S; Black S; Bocti C; Borrie M; Feldman H; Freedman M; Hsiung R; Kirk A; Masellis M; Nygaard H; Rajji T; Verret L; 34912492
PSYCHOLOGY
9 Recommendations of the 5th Canadian Consensus Conference on the diagnosis and treatment of dementia. Ismail Z, Black SE, Camicioli R, Chertkow H, Herrmann N, Laforce R, Montero-Odasso M, Rockwood K, Rosa-Neto P, Seitz D, Sivananthan S, Smith EE, Soucy JP, Vedel I, Gauthier S, CCCDTD5 participants 32725777
PERFORM
10 Clinical judgement is paramount when performing cognitive screening during COVID-19. Phillips NA, Andrews M, Chertkow H, Pichora-Fuller MK, Rockwood K, Wittich W 32396983
PSYCHOLOGY
11 Special issues on using the MoCA for remote assessment during COVID-19 2. Phillips NA, Chertkow H, Pichora-Fuller MK, Wittich W 32253754
PSYCHOLOGY
12 The Comprehensive Assessment of Neurodegeneration and Dementia: Canadian Cohort Study. Chertkow H, Borrie M, Whitehead V, Black SE, Feldman HH, Gauthier S, Hogan DB, Masellis M, McGilton K, Rockwood K, Tierney MC, Andrew M, Hsiung GR, Camicioli R, Smith EE, Fogarty J, Lindsay J, Best S, Evans A, Das S, Mohaddes Z, Pilon R, Poirier J, Phillips NA, MacNamara E, Dixon RA, Duchesne S, MacKenzie I, Rylett RJ 31309917
PSYCHOLOGY
13 Functional and anatomical memory indices in patients with or at risk for Alzheimer's disease. Phillips NA, Chertkow H, Leblanc MM, Pim H, Murtha S 15012840
PSYCHOLOGY

 

Title:Public Health
Authors:Gurve DCenten APSlack PJDang-Vu TTBelleville SAnderson NDMontero-Odasso MNygaard HBChertkow HFeldman HHBrewster PWHLim A
Link:https://pubmed.ncbi.nlm.nih.gov/41434309/
DOI:10.1002/alz70860_107491
Publication:Alzheimer s & dementia : the journal of the Alzheimer s Association
Keywords:
PMID:41434309 Category: Date Added:2025-12-23
Dept Affiliation: PERFORM
1 University of Toronto, Toronto, ON, Canada.
2 Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
3 University of British Columbia, Vancouver, BC, Canada.
4 Centre de recherche de l'Institut universitaire de gériatrie de Montréal, Montreal, QC, Canada.
5 PERFORM Centre, Concordia University, Montreal, QC, Canada.
6 Concordia University, Montreal, QC, Canada.
7 Research Centre, Institut universitaire de gériatrie de Montréal, Montreal, QC, Canada.
8 Department of Psychology, Université de Montréal, Montreal, QC, Canada.
9 Rotman Research Institute, Baycrest Academy for Research and Education, Toronto, ON, Canada.
10 Rotman Research Institute, Toronto, ON, Canada.
11 Ben & Hilda Katz Interprofessional Research Centre in Geriatric and Dementia Care, Toronto, ON, Canada.
12 Kimel Family Centre for Brain Health and Wellness, Toronto, ON, Canada.
13 Western Univeristy, London, ON, Canada.
14 Lawson Health Research Institute, London, ON, Canada.
15 Schulich School of Medicine & Dentistry, Division of Geriatric Medicine, Western University, London, ON, Canada.
16 UBC Hospital Clinic for Alzheimer Disease and Related Disorders, Vancouver, BC, Canada.
17 Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
18 Kimel Family Centre for Brain Health and Wellness and Anne & Allan Bank Centre for Clinical Research Trials, Baycrest Health Sciences, Toronto, ON, Canada.
19 Baycrest and Rotman Research Institute, Toronto, ON, Canada.
20 Baycrest Academy, Toronto, ON, Canada.
21 University of California San Diego, Department of Neurosciences, La Jolla, CA, USA.
22 Alzheimer's Disease Cooperative Study (ADCS), University of California San Diego, La Jolla, CA, USA.
23 Cognition & Technology Research Group, Institute on Aging and Lifelong Health, University of Victoria, Victoria, BC, Canada.
24 University of Victoria, Victoria, BC, Canada.

Description:

Background: Older adults experience considerable day-to-day variability in cognitive function. We aimed to test the hypothesis that this is in part related to sleep, and determine which EEG sleep features are most important in supporting day to day cognitive resilience.

Method: We analyzed data from 149 adults at high risk for dementia participating in the Brain Health Pro (BHPro) study. At BHPro baseline, participants underwent up to 3 nights of overnight ambulatory EEG using the MUSE-S (Interaxon, Toronto, Canada) as well as multi-day app-based cognitive testing (MyCogHealth, Victoria, Canada). Of 350 participants, 149 had EEG and cognitive evaluation that overlapped by at least 1 day. We performed automated sleep staging and computed frontal NREM (N2 and N3) delta power and REM theta power. We used linear mixed effect models to relate each morning's composite global cognitive test results to the previous night's sleep measures.

Result: 149 individuals had >=1 cognitive evaluation within 12 hours of an overnight EEG recording. Of these, 63 had 2 nights, and 37 had >=3 nights. Greater % REM sleep (+0.15 per 1SD greater REM sleep, SE 0.04 p = 0.0001) and relative REM theta power (+0.08 per 1SD greater relative REM theta power, SE 0.04, p = 0.02) the night before were associated with better cognitive performance the next morning, and there was a non-significant positive relationship (+0.06 per 1SD difference, SE 0.04, p = 0.11) between NREM delta power and cognitive performance the following morning. These effects were particularly strong in those with mild cognitive impairment (delta power interaction p = 0.055; theta power interaction p = 0.02) CONCLUSION: REM sleep theta power and NREM delta power may support day to day cognitive performance in older adults at high risk for dementia, particularly those with mild cognitive impairment, and may represent electrophysiologic therapeutic targets to support cognitive resilience.





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