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Do stimulant medications produce sensitization in humans?

Author(s): Marco Leyton

No abstract

Article GUID: 35398453


Estrogen receptors observed at extranuclear neuronal sites and in glia in the nucleus accumbens core and shell of the female rat: Evidence for localization to catecholaminergic and GABAergic neurons

Author(s): Almey A; Milner TA; Brake WG;

Estrogens affect dopamine-dependent diseases/behavior and have rapid effects on dopamine release and receptor availability in the nucleus accumbens (NAc). Low levels of nuclear estrogen receptor (ER) a and ERß are seen in the NAc, which cannot account for the rapid effects of estrogens in this region. G-protein coupled ER 1 (GPER1) is observed at low leve ...

Article GUID: 35397175


Physicochemical change and microparticle release from disposable gloves in the aqueous environment impacted by accelerated weathering

Author(s): Wang Z; An C; Lee K; Chen X; Zhang B; Yin J; Feng Q;

The explosive growth of disposable gloves usage in cities around the world has posed a considerable risk to municipal solid management and disposal during the COVID-19 pandemic. The lack of the environmental awareness leads to glove waste being discarded randomly and ending up in the soil and/or the ocean ecosystem. To explore the physicochemical changes ...

Article GUID: 35395312


Teaching Culturally Safe Care in Simulated Cultural Communication Scenarios During the COVID-19 Pandemic: Virtual Visits with Indigenous Animators

Author(s): Maar M; McGregor L; Desjardins D; Delaney KZ; Bessette N; Reade M;

Clinical learning activities involving Indigenous patient actors that specifically address the development of culturally safe care skills among medical students are important in order to improve health care for Indigenous people. In 2020, the COVID-19 pandemic led to strict physical distancing regulations and regional lockdowns that made the in-person del ...

Article GUID: 35392591


Acceptability of Serious Games in Pediatric Asthma Education and Self-management: Pilot Study

Author(s): Silva-Lavigne N; Valderrama A; Pelaez S; Bransi M; Balli F; Gervais Y; Gaudy T; Tse SM;

Background: Asthma is the most common chronic pediatric disease. Despite existing tools to manage asthma, 40%-55% of children with asthma experience uncontrolled asthma. Serious games (SGs) represent a novel approach in promoting asthma education and self-management for children. Objective: In this qualitative pilot study with an embedded quantitative de ...

Article GUID: 35389354


Direct sound printing

Author(s): Habibi M; Foroughi S; Karamzadeh V; Packirisamy M;

Photo- and thermo-activated reactions are dominant in Additive Manufacturing (AM) processes for polymerization or melting/deposition of polymers. However, ultrasound activated sonochemical reactions present a unique way to generate hotspots in cavitation bubbles with extraordinary high temperature and pressure along with high heating and cooling rates whi ...

Article GUID: 35387993


Naturalistic Parent Teaching in the Home Environment During Early Childhood

Author(s): Della Porta SL; Sukmantari P; Howe N; Farhat F; Ross HS;

Children's sociocultural experiences in their day-to-day lives markedly play a key role in learning about the world. This study investigated parent-child teaching during early childhood as it naturally occurs in the home setting. Thirty-nine families' naturalistic interactions in the home setting were observed; 1033 teaching sequences were identif ...

Article GUID: 35386906


Dynamic and Reprocessable Fluorinated Poly(hindered urea) Network Materials Containing Ionic Liquids to Enhance Triboelectric Performance

Author(s): Nellepalli P; Kim MP; Park J; Noh SM; Ye Z; Jung HW; Ko H; Oh JK;

Triboelectric nanogenerators (TENGs), a newly developed energy harvesting device that converts surrounding environmental mechanical stimuli into electricity, have been significantly explored as an ideal long-term power source for electrical devices. Despite recent advances, the development of advanced TENG devices with sufficient outputs to sustainably po ...

Article GUID: 35385641


Vulnerabilities in clinician-parent exchanges and the cascade of communication traps: a review

Author(s): Ferretti E; Schoenherr JR; Mattiola A; Daboval T;

This review considers parent-clinician interactions that are associated with vulnerabilities in communication and what we refer to as 'communication traps'. Communication traps are defined by high-stress situations with affect-laden subject matter that can lead to progressively dysfunctional communications/exchanges that are avoidable. While this ...

Article GUID: 35383036


Understanding national trends in COVID-19 vaccine hesitancy in Canada: results from five sequential cross-sectional representative surveys spanning April 2020-March 2021

Author(s): Lavoie K; Gosselin-Boucher V; Stojanovic J; Gupta S; Gagné M; Joyal-Desmarais K; Séguin K; Gorin SS; Ribeiro P; Voisard B; Vallis M; Corace K; Presseau J; Bacon S;

Objective: To examine rates of vaccine hesitancy and their correlates among Canadian adults between April 2020 and March 2021. Design: Five sequential cross-sectional age, sex and province-weighted population-based samples who completed online surveys. Setting: Canada. Participants: A total of ...

Article GUID: 35383087


Effects of Transcranial Direct Current Stimulation on Attentional Bias to Methamphetamine Cues and Its Association With EEG-Derived Functional Brain Network Topology

Author(s): Khajehpour H; Parvaz MA; Kouti M; Hosseini Rafsanjani T; Ekhtiari H; Bakht S; Noroozi A; Makkiabadi B; Mahmoodi M;

Background: Although transcranial direct current stimulation (tDCS) has shown to potentially mitigate drug craving and attentional bias to drug-related stimuli, individual differences in such modulatory effects of tDCS are less understood. In this study, we aimed to investigate a source of the in ...

Article GUID: 35380672


Predicted coronavirus Nsp5 protease cleavage sites in the human proteome

Author(s): Scott BM; Lacasse V; Blom DG; Tonner PD; Blom NS;

Background: The coronavirus nonstructural protein 5 (Nsp5) is a cysteine protease required for processing the viral polyprotein and is therefore crucial for viral replication. Nsp5 from several coronaviruses have also been found to cleave host proteins, disrupting molecular pathways involved in innate immunity. Nsp5 from the recently emerged SARS-CoV-2 vi ...

Article GUID: 35379171


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