1 Faculté des Sciences et Technologies BP 70239, UMR1136 INRA-Université de Lorraine "Interactions Arbres/Micro-organismes", Université de Lorraine, Vandoeuvre-lès-Nancy Cedex, F-54506, France.
2 Faculté des Sciences et Technologies BP 70239, UMR1136 INRA-Université de Lorraine "Interactions Arbres/Micro-organismes", INRA, Vandoeuvre-lès-Nancy Cedex, F-54506, France.
3 Fungal Physiology, CBS-KNAW Fungal Biodiversity Centre & Fungal Molecular Physiology, Utrecht University, Uppsalalaan 8, Utrecht, 3584 CT, The Netherlands.
4 Center for Structural and Functional Genomics, Concordia University, 7141 Sherbrooke Street West, Montreal, QC, H4B 1R6, Canada.

Secretion of small proteins is species-specific within Aspergillus sp.

Microb Biotechnol. 2017 03;10(2):323-329

Authors: Valette N, Benoit-Gelber I, Falco MD, Wiebenga A, de Vries RP, Gelhaye E, Morel-Rouhier M

Abstract

Small secreted proteins (SSP) have been defined as proteins containing a signal peptide and a sequence of less than 300 amino acids. In this analysis, we have compared the secretion pattern of SSPs among eight aspergilli species in the context of plant biomass degradation and have highlighted putative interesting candidates that could be involved in the degradative process or in the strategies developed by fungi to resist the associated stress that could be due to the toxicity of some aromatic compounds or reactive oxygen species released during degradation. Among these candidates, for example, some stress-related superoxide dismutases or some hydrophobic surface binding proteins (HsbA) are specifically secreted according to the species . Since these latter proteins are able to recruit lytic enzymes to the surface of hydrophobic solid materials and promote their degradation, a synergistic action of HsbA with the degradative system may be considered and need further investigations. These SSPs could have great applications in biotechnology by optimizing the efficiency of the enzymatic systems for biomass degradation.

PMID: 27153937 [PubMed - indexed for MEDLINE]