Author(s): Leir TMW; Gardner MPH;
New results help address a longstanding debate regarding which learning strategies allow animals to anticipate negative events based on past associations between sensory stimuli.
Article GUID: 40146623
Author(s): Van Hulst A; Zheng S; Argiropoulos N; Ybarra M; Ball GDC; Kakinami L;
The World Health Organization recommends using + 2 SD of body mass index z-score (zBMI) to define overweight/obesity (OWO) in children ages 2 to 5 years whereas + 1 SD is used as cut-point from 5 years onwards. Empirical evidence for using different cut-points across childhood is lacking. Our objective was to compare the ability of OWO in early childhood ...
Article GUID: 40140102
Author(s): Nguyen PV; Dang-Vu TT; Forest G; Desjardins S; Forget MF; Vu TT; Nguyen QD; Kouassi E; Desmarais P;
Background: Mirtazapine promotes sleep by blocking serotonin and histaminergic receptors and is often used off-label to treat chronic insomnia. However, its efficacy remains to be demonstrated in a clinical trial. The MIRAGE study aims to determine the efficacy and safety of mirtazapine in older ...
Article GUID: 40135470
Author(s): Goulet D; Boivin M; Gravel C; Little J; Ouellet-Morin I; Gouin JP; Dubois L;
The lack of polygenic scores (PGSs) developed for body-mass index (BMI) in children may be problematic because the genetic architecture characterizing BMI changes throughout life. This study aims to describe the genetic susceptibility to obesity in children and to compare two PGSs based on data from adults and children and their association with BMI and d ...
Article GUID: 40132211
Author(s): Bögershausen N; Cavdarli B; Nagai T; Milev MP; Wolff A; Mehranfar M; Schmidt J; Choudhary D; Gutiérrez-Gutiérrez Ó; Cyganek L; Saint-Dic D; Zibat A; Köhrer K; Wollenweber TE; Wieczorek D; Altmüller J; Borodina T; Kaçar D; Haliloglu G; Li ...
As a major component of intracellular trafficking, the coat protein complex II (COPII) is indispensable for cellular function during embryonic development and throughout life. The four SEC24 proteins (A-D) are essential COPII components involved in cargo selection and packaging. A human disorder ...
Article GUID: 40131364
Author(s): Hervé V; Bonenfant L; Amyot M; Balafrej R; Ali OBK; Benali H; Brouillette J;
In Alzheimer's disease, there is an imbalance in neurotransmitter release and altered neuronal activation. Here, we present a protocol approach to analyze neuronal activity by combining local field potential (LFP) recording with microdialysis within the same animal. We describe steps for measuring glutamate and GABA levels following hippocampal amyloi ...
Article GUID: 40131934
Author(s): Lecomte L; Ferchaud AL; Normandeau E; Mérot C; Langlois-Parisé I; Therrien JC; Bérubé P; Djambazian H; Nawarathna PM; Ragoussis J; Fraser D;
Brook trout (Salvelinus fontinalis) is a socioeconomically important fish species for fisheries, aquaculture and aquatic conservation. We produced a 2.5 Gb reference assembly by combining Hi-C chromosome conformation capture with high-coverage short- and long-read sequencing of a fully homozygous ...
Article GUID: 40130537
Author(s): Avigdor T; Ren G; Abdallah C; Dubeau F; Grova C; Frauscher B;
Morning awakening is part of everyday life. Surprisingly, information remains scarce on its underlying neurophysiological correlates. Here simultaneous polysomnography and stereo-electroencephalography recordings from 18 patients are used to assess the spectral and connectivity content of the process of awakening at a local level 15 min before and after t ...
Article GUID: 40126936
Author(s): Bokhari R; Bisson DG; Fortin M; Vigouroux M; Cata JP; Hwang KP; Chen MM; Ceniza-Bordallo G; Ouellet JA; Ingelmo PM;
Introduction: Pain in lower back is a common condition reported by astronauts, both during and after space missions. Investigating the alterations in the spine and the mechanisms driving these changes is essential for a deeper understanding of how microgravity impacts the human spine. This knowle ...
Article GUID: 40124538
Author(s): Aïmen E Gheribi
In recent years, there has been a renewed interest in accurately quantifying the ion's transference number within molten salts. Surprisingly, despite efforts to address the severe lack of experimental data, there is still no reliable theoretical framework that establishes a clear link between the transference number and simulated phase trajectories th ...
Article GUID: 40124059
Author(s): Sun Y; Bakhtiari S; Valente-Paterno M; Jiang H; Zerges W;
A small genome in chloroplasts encodes many of the polypeptide subunits of the photosynthetic electron transport complexes embedded in the membranes of thylakoid vesicles in the chloroplast stroma and synthesized by ribosomes of the bacterial-like genetic system of this semiautonomous organelle. While thylakoid membranes are sites of translation, evidence ...
Article GUID: 40116843
Author(s): Bouchard R; Babin C; Normandeau E; Xuereb A; Boulanger F; Coxon A; Diamond S; Fireman R; Lameboy J; Louttit N; Natawapineskum G; Okimaw D; Torio D; Varty S; Moore JS; Fraser D; Bernatchez L;
Dispersal is a highly variable trait influenced by life history and ecological factors, affecting gene flow when dispersers successfully reproduce. Anadromous salmonids, with their diverse migratory strategies and ecological traits, serve as an ideal model for studying dispersal evolution, showca ...
Article GUID: 40108992
