Author(s): Zhu N; Xie WF;

In this article, a distributed control strategy using an adaptive sliding mode controller (ASMC) is proposed for a 13-degree-of-freedom (13-DOF) cooperative robotic system in the field of automated fiber placement (AFP). A distributed control structure with event-triggered mechanism is developed to guarantee the desired cooperation performance and reduce ...

Article GUID: 40436653

Author(s): Roshanfar M; Salimi M; Jang SJ; Sinusas AJ; Kim J; Mosadegh B;

Background: Image-guided navigation has revolutionized precision cardiac interventions, yet current technologies face critical limitations in real-time guidance and procedural accuracy. Method: Here, we comprehensively evaluate state-of-the-art imaging modalities, from conventional fluoroscopy to emerging hybrid systems, analyzing their applications acros ...

Article GUID: 40428106

Author(s): Eskandari K; Bélanger SM; Lachance V; Kourrich S;

Neurodegenerative disorders, such as Alzheimer's, Parkinson's, and Huntington's disease, due to their multifaced and complicated nature, remain uncurable and impose substantial financial and human burdens on society. Therefore, developing new innovative therapeutic strategies is vital. In this context, drug repurposing has emerged as a promisi ...

Article GUID: 40430519

Author(s): Mignacca M; Brugiapaglia S; Bramburger JJ;

Dynamic mode decomposition (DMD) is a numerical method that seeks to fit time-series data to a linear dynamical system. In doing so, DMD decomposes dynamic data into spatially coherent modes that evolve in time according to exponential growth/decay or with a fixed frequency of oscillation. A widespread application of DMD has been to video, where one inter ...

Article GUID: 40421310

Author(s): Raheja Y; Singh V; Gaur VK; Tsang A; Chadha BS;

In this study, two thermostable endoglucanases (Rem_GH5EG and Rem_GH7EG) from Rasamsonia emersonii were heterologously expressed in Pichia pastoris and characterized to evaluate their potential for industrial biomass saccharification. Rem_GH5EG demonstrated markedly superior catalytic efficiency toward barley ß-glucan (kcat/Km = 6.3 × 10-3/mg mL/min), whi ...

Article GUID: 40418313

Author(s): Gagné N; Greenlaw KM; Coffey EBJ;

Hearing-in-noise (HIN) is a challenging task that is essential to human functioning in social, vocational, and educational contexts. Successful speech perception in noisy settings is thought to rely in part on the brain's ability to enhance neural representations of attended speech. In everyday HIN situations, important features of speech (i.e., pitch ...

Article GUID: 40412301

Author(s): Gholizadeh F; Hajiaghayi M; Choi JS; Little SR; Rahbari N; Kargar M; Brotto K; Han E; Shih SCC; Darlington PJ;

Memory T helper (Th) cells, generated in response to immunogenic challenges, are crucial in orchestrating adaptive immune responses. Acetylcholine (ACh), a key neurotransmitter of the parasympathetic nervous system, modulates immune function via muscarinic ACh receptors (mAChRs). This study inves ...

Article GUID: 40405417

Author(s): Jones Z; Drouin S; Kersten-Oertel M;

Purpose: Virtual reality (VR) can offer immersive platforms for segmenting complex medical images to facilitate a better understanding of anatomical structures for training, diagnosis, surgical planning, and treatment evaluation. These applications rely on user interaction within the VR environment to manipulate and interpret medical data. However, the op ...

Article GUID: 40402355

Author(s): Bin X; Pawelek PD;

The Escherichia coli enterobactin biosynthetic protein EntB is a bifunctional enzyme that catalyzes hydrolysis of isochorismate via its N-terminal isochorismatase (IC) domain, and then transfers phosphopantetheinylated 2,3-DHB to EntF via the EntB C-terminal aryl carrier protein (ArCP) domain. Here we used a fluorescence anisotropy binding assay to invest ...

Article GUID: 40400396

Author(s): Avigdor T; Peter-Derex L; Ho A; Schiller K; Wang Y; Abdallah C; Delaire E; Jaber K; Travnicek V; Grova C; Frauscher B;

Although rapid eye movement (REM) sleep is often thought of as a singular state, it consists of two substates, phasic and tonic REM, defined by the presence (respectively absence) of bursts of rapid eye movements. These two substates have distinct EEG signatures and functional properties. However ...

Article GUID: 40394955

Author(s): Schebb NH; Kampschulte N; Hagn G; Plitzko K; Meckelmann SW; Ghosh S; Joshi R; Kuligowski J; Vuckovic D; Botana MT; Sánchez-Illana Á; Zandkarimi F; Das A; Yang J; Schmidt L; Checa A; Roche HM; Armando AM; Edin ML; Lih FB; Aristizabal-Hena ...

Several oxylipins are potent lipid mediators that regulate diverse aspects of health and disease and whose quantitative analysis by liquid chromatography-mass spectrometry (LC-MS) presents substantial technical challenges. As members of the lipidomics community, we developed technical recommendat ...

Article GUID: 40392938

Author(s): Gumuchian ST; Boyle A; Kennedy G; Wong SF; Ellenbogen MA;

Despite high recurrence rates in major depressive disorder (MDD), little is known about the factors influencing recurrence. Understanding the changes that occur between major depressive episodes (MDEs) is imperative. It is possible that being fearful of experiencing another MDE may lead to cognitive and behavioural changes that increase MDD recurrence ris ...

Article GUID: 40391691