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Towards user-centered interactive medical image segmentation in VR with an assistive AI agent

Author(s): Spiegler P; Harirpoush A; Xiao Y;

Crucial in disease analysis and surgical planning, manual segmentation of volumetric medical scans (e.g. MRI, CT) is laborious, error-prone, and challenging to master, while fully automatic algorithms can benefit from user feedback. Therefore, with the complementary power of the latest radiological AI foundation models and virtual reality (VR)'s intui ...

Article GUID: 41509996


The Role of the Posterior Paraventricular Nucleus of the Thalamus in Food Deprivation-Induced Heroin-Seeking Relapse, in Male and Female Rats

Author(s): Borges C; Darecka A; Mainville-Berthiaume A; Ah-Yen E; Darvishmolla M; Courtemanche R; Shalev U;

Abstinence from drug use is often the result of the associated negative consequences. However, relapse occurs in a large proportion of abstinent users, and the underlying brain mechanisms are not clear. An arguably relevant brain area is the posterior paraventricular nucleus of the thalamus (pPVT ...

Article GUID: 41506524


The ELEVATE-LBP consortium: exercise &amp, evidence to lead effective vital action in translating excellence for low back pain prevention

Author(s): Sheeran L; McIlroy S; Wong AYL; Anderson DB; Samartzis D; Bogaert L; Domokos B; Spang C; Fortin M; Hodges PW; Bizzini M; Dvorák J;

Article GUID: 41507623


Preexisting Mental Health Disorders Are Associated With Acute Clinical Presentation and Longitudinal Recovery Trajectories in Adolescents With Concussion

Author(s): Iuliano SG; Gagnon IJ; Iverson GL; Cook NE; Zemek R; Teel EF;

This secondary analysis examined the association between preexisting mental health conditions and clinical recovery trajectories in adolescents with concussion. Adolescents (13-17; n = 1238) completed clinical assessments (Post-Concussion Symptom Inventory [PCSI] =48 hours postinjury; PCSI/ Pediatric Quality of Life [PedsQL] for 3 months) and were categor ...

Article GUID: 41505351


Cross-species evaluation of TANGO2 homologs, including HRG-9 and HRG-10 in em Caenorhabditis elegans, /em challenges a proposed role in heme trafficking

Author(s): Sandkuhler SE; Youngs KS; Gottipalli O; Owlett LD; Bandora MB; Naaz A; Kim E; Wang L; Wojtovich A; Gupta V; Sacher M; Mackenzie SJ;

Mutations in the TANGO2 gene are associated with a severe neurometabolic disorder in humans, often presenting with life-threatening metabolic crisis. However, the function of TANGO2 protein remains unknown. It has recently been proposed that TANGO2 transports heme within and between cells, from a ...

Article GUID: 41504601


Lignin phenol abundances and ratios are modulated by their interactions with iron hydroxides in sediments

Author(s): Moritz A; Ezzati M; Gélinas Y;

Iron hydroxides play a key role in the preservation of organic matter in soils and sediments, yet the specificity and extent of their interactions with lignin-derived phenols-important source indicators for terrestrial organic matter-remain poorly understood in aquatic systems. In this study, we analyzed surface and downcore sediments along the terrestria ...

Article GUID: 41500137


Proximal sound printing: direct 3D printing of microstructures on polymers

Author(s): Foroughi S; Habibi M; Packirisamy M;

Proximal Sound Printing (PSP) is a new class of additive manufacturing (AM) processes where on-demand polymerization occurs through ultrasound waves interacting with printing material right at the proximity of the acoustic aperture by inducing cavitation. Despite recent developments in sound-based AM techniques, inherent practical limitations still remain ...

Article GUID: 41500993


Biomarkers

Author(s): Zhou J; Wearn A; Huck J; Hughes CS; Baracchini G; Sylvain E; Tremblay-Mercier J; Poirier J; Breitner JCSCS; Villeneuve S; Chakravarty MM; Tardif CL; Gauthier CJ; Daugherty AM; Turner GR; Spreng RN;

Background: Elevated brain iron deposition is recognized as a characteristic of normal aging and neurodegenerative diseases, particularly Alzheimer's disease (AD), where it correlated with amyloid-ß plaques and neurofibrillary tangles. Our study aimed to investigate the relationship between l ...

Article GUID: 41499788


Statistical shape model-based estimation of registration error in computer-assisted total knee arthroplasty

Author(s): Gheflati B; Mirzaei M; Zuhars J; Rottoo S; Rivaz H;

Purpose: Computer-assisted surgical navigation systems have been developed to improve the precision of total knee arthroplasty (TKA) by providing real-time guidance on implant alignment relative to patient anatomy. However, surface registration remains a key source of error that can propagate through the surgical workflow. This study investigates how pati ...

Article GUID: 41495592


Metaphors in context and in isolation: Familiarity, aptness, concreteness, metaphoricity, and structure norms for 300 two-word expressions

Author(s): Pissani L; de Almeida RG;

Familiarity, aptness, concreteness, metaphoricity, and structural norms for 300 two-word English metaphorical expressions (e.g., broken heart, early bird), presented in sentence context and in isolation, were obtained from 164 participants. Familiarity was conceived as the extent to which participants had previously heard or read that expression. Aptness ...

Article GUID: 41491452


Towards smart PFAS management: Integrating artificial intelligence in water and wastewater systems

Author(s): Yaghoobian S; An J; Jeong DW; Hwang JH;

Artificial intelligence (AI) and machine learning (ML) are increasingly integrated into Per- and polyfluoroalkyl substances (PFAS) research; however, the field remains fragmented with substantial variation in modeling objectives. This review provides one of the most comprehensive and detailed syntheses to date of AI/ML methods across the PFAS contaminatio ...

Article GUID: 41483514


Adaptive sliding mode fault-tolerant control of an over-actuated hybrid VTOL fixed-wing UAV under transition flight

Author(s): Wang B; Zhao H; Hu X; Shen Y; Li N;

In this study, an innovative adaptive sliding mode fault-tolerant control approach is developed for an over-actuated vertical takeoff and landing (VTOL) fixed-wing unmanned aerial vehicle (UAV) with the capability to suppress overestimation of adaptive parameters. This method is designed to effectively address model uncertainties and actuator faults witho ...

Article GUID: 41475926


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