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Human-level COVID-19 diagnosis from low-dose CT scans using a two-stage time-distributed capsule network

Author(s): Afshar P; Rafiee MJ; Naderkhani F; Heidarian S; Enshaei N; Oikonomou A; Babaki Fard F; Anconina R; Farahani K; Plataniotis KN; Mohammadi A;

Reverse transcription-polymerase chain reaction is currently the gold standard in COVID-19 diagnosis. It can, however, take days to provide the diagnosis, and false negative rate is relatively high. Imaging, in particular chest computed tomography (CT), can assist with diagnosis and assessment of ...

Article GUID: 35318368


A Versatile Transcription Factor Biosensor System Responsive to Multiple Aromatic and Indole Inducers

Author(s): Nasr MA; Timmins LR; Martin VJJ; Kwan DH;

Allosteric transcription factor (aTF) biosensors are valuable tools for engineering microbes toward a multitude of applications in metabolic engineering, biotechnology, and synthetic biology. One of the challenges toward constructing functional and diverse biosensors in engineered microbes is the limited toolbox of identified and characterized aTFs. To ov ...

Article GUID: 35316041


Global urban environmental change drives adaptation in white clover

Author(s): Santangelo JS; Ness RW; Cohan B; Fitzpatrick CR; Innes SG; Koch S; Miles LS; Munim S; Peres-Neto PR; Prashad C; Tong AT; Aguirre WE; Akinwole PO; Alberti M; Álvarez J; Anderson JT; Anderson JJ; Ando Y; Andrew NR; Angeoletto F; Anstett DN ...

Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense th ...

Article GUID: 35298255


Biallelic variants in TRAPPC10 cause a microcephalic TRAPPopathy disorder in humans and mice

Author(s): Rawlins LE; Almousa H; Khan S; Collins SC; Milev MP; Leslie J; Saint-Dic D; Khan V; Hincapie AM; Day JO; McGavin L; Rowley C; Harlalka GV; Vancollie VE; Ahmad W; Lelliott CJ; Gul A; Yalcin B; Crosby AH; Sacher M; Baple EL;

The highly evolutionarily conserved transport protein particle (TRAPP) complexes (TRAPP II and III) perform fundamental roles in subcellular trafficking pathways. Here we identified biallelic sequence alterations in TRAPPC10, a component of the TRAPP II complex, in individuals with a severe micro ...

Article GUID: 35298461


Social gradients in ADHD by household income and maternal education exposure during early childhood: Findings from birth cohort studies across six countries

Author(s): Nicholas James Spencer

CONCLUSION: Findings indicate that children in families with high household income or maternal education are less likely to have ADHD at age 9-11. Absolute inequality, in combination with relative inequality, provides a more complete account of the socioeconomic status and ADHD relationship in different high-income countries. While the study design preclu ...

Article GUID: 35294456


Comparing microscopy and DNA metabarcoding techniques for identifying cyanobacteria assemblages across hundreds of lakes

Author(s): MacKeigan PW; Garner RE; Monchamp MÈ; Walsh DA; Onana VE; Kraemer SA; Pick FR; Beisner BE; Agbeti MD; da Costa NB; Shapiro BJ; Gregory-Eaves I;

Accurately identifying the species present in an ecosystem is vital to lake managers and successful bioassessment programs. This is particularly important when monitoring cyanobacteria, as numerous taxa produce toxins and can have major negative impacts on aquatic ecosystems. Increasingly, DNA-ba ...

Article GUID: 35287928


Analysis of input set characteristics and variances on k-fold cross validation for a Recurrent Neural Network model on waste disposal rate estimation

Author(s): Vu HL; Ng KTW; Richter A; An C;

The use of machine learning techniques in waste management studies is increasingly popular. Recent literature suggests k-fold cross validation may reduce input dataset partition uncertainties and minimize overfitting issues. The objectives are to quantify the benefits of k-fold cross validation for municipal waste disposal prediction and to identify the r ...

Article GUID: 35287077


Nitrogen and organic load removal from anaerobically digested leachate using a hybrid electro-oxidation and electro-coagulation process

Author(s): Choudhury MR; Rajagopal R; Meertens W; Rahaman MS;

This study evaluated the performance of an integrated electrochemical process, which simultaneously utilizes electro-oxidation (EO) and electro-coagulation (EC) methods while removing organic and nitrogen loads from high-strength leachate obtained from anaerobic digesters. A bipolar arrangement of the aluminum electrode, sandwiched between a monopolar bor ...

Article GUID: 35276557


Incorporation of Optical Density into the Blending Design for a Biocement Solution

Author(s): Fukue M; Lechowicz Z; Fujimori Y; Emori K; Mulligan CN;

The engineering practices for applying the microbial precipitation of carbonates require a design of the blending biocement solution (BCS). The BCS is usually blended with concentrated strains NO-A10, reaction media, such as urea and CaCl2, and a solvent, i.e., water or seawater. To characterize the BCS, the unknown microbial characteristics, such as the ...

Article GUID: 35269187


Extending Effective Dynamic Range of Hyperspectral Line Cameras for Short Wave Infrared Imaging

Author(s): Shaikh MS; Jaferzadeh K; Thörnberg B;

In this work, a multi-exposure method is proposed to increase the dynamic range (DR) of hyperspectral imaging using an InGaAs-based short-wave infrared (SWIR) hyperspectral line camera. Spectral signatures of materials were captured for scenarios in which the DR of a scene was greater than the DR of a line camera. To demonstrate the problem and test the p ...

Article GUID: 35270968


A real-time web tool for monitoring and mitigating indoor airborne COVID-19 transmission risks at city scale

Author(s): Albettar M; Leon Wang L; Katal A;

Airborne transmission of aerosols contributes to a large portion of the SARS-CoV-2 spread indoors. This study develops a real-time interactive web-based platform for the public to compare various strategies to curb indoor airborne transmission of COVID-19 in different archetype buildings at a city scale. Although many countries have started vaccination an ...

Article GUID: 35261876


Changes in Youth Mental Health, Psychological Wellbeing, and Substance Use During the COVID-19 Pandemic: A Rapid Review

Author(s): Zolopa C; Burack JA; O' Connor RM; Corran C; Lai J; Bomfim E; DeGrace S; Dumont J; Larney S; Wendt DC;

Since the onset of the COVID-19 pandemic, researchers around the world have made efforts to assess its impact on youth mental health; however, the breadth of this topic has impeded a clear assessment of pandemic outcomes. This study aimed to address this gap by reviewing changes in youth (age = 2 ...

Article GUID: 35252542


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