Keyword search (4,163 papers available)

"systemic" Keyword-tagged Publications:

Title Authors PubMed ID
1 Understanding COVID-19 vaccination disparity among Black adults in North America: A two-study motivational approach Fang X; Holding AC; Audet ÉC; Thai H; Koestner R; 41043306
PSYCHOLOGY
2 Comparative Analysis of the Functions Work Groups and Informal Subgroups Carry out in Relation to their Members: The Essence, Conditions of Implementation, Effects, and Dysfunctions Sidorenkov AV; Borokhovski EF; 38492193
CONCORDIA
3 Candidiasis: from cutaneous to systemic, new perspectives of potential targets and therapeutic strategies Lu H; Hong T; Jiang Y; Whiteway M; Zhang S; 37307922
BIOLOGY
4 Survey of Cooperative Advanced Driver Assistance Systems: From a Holistic and Systemic Vision González-Saavedra JF; Figueroa M; Céspedes S; Montejo-Sánchez S; 35459025
ENCS
5 Protocol for a partially nested randomised controlled trial to evaluate the effectiveness of the scleroderma patient-centered intervention network COVID-19 home-isolation activities together (SPIN-CHAT) program to reduce anxiety among at-risk scleroderma patients. Thombs BD, Kwakkenbos L, Carrier ME, Bourgeault A, Tao L, Harb S, Gagarine M, Rice D, Bustamante L, Ellis K, Duchek D, Wu Y, Bhandari PM, Neupane D, Carboni-Jiménez A, Henry RS, Krishnan A, Sun Y, Levis B, He C, Turner KA, Benedetti A, Culos-Reed N, El-Baalbaki G, Hebblethwaite S, Bartlett SJ, Dyas L, Patten S, Varga J, Scleroderma Patient-centered Intervention Network (SPIN) COVID-19 Patient Advisory Team, SPIN Investigators 32521358
PSYCHOLOGY
6 Protocol for a partially nested randomised controlled trial to evaluate the effectiveness of the scleroderma patient-centered intervention network COVID-19 home-isolation activities together (SPIN-CHAT) program to reduce anxiety among at-risk scleroderma patients. Fortuné C, Gietzen A, Guillot G, Lewis N, Nielsen K, Richard M, Sauvé M, Welling J, SPIN Investigators, Baron M, Furst DE, Gottesman K, Malcarne V, Mayes MD, Mouthon L, Nielson WR, Riggs R, Wigley F, Assassi S, Boutron I, Ells C, van den Ende C, Fligelstone K, Frech T, Godard D, Harel D, Hinchcliff M, Hudson M, Johnson SR, Larche M, Leite C, Nguyen C, Pope J, Portales A, Rannou F, Reyna TSR, Schouffoer AA, Suarez-Almazor ME, Agard C, Albert A, André M, Arsenault G, Benzidia I, Bernstein EJ, Berthier S, Biss 32419703
PSYCHOLOGY

 

Title:Candidiasis: from cutaneous to systemic, new perspectives of potential targets and therapeutic strategies
Authors:Lu HHong TJiang YWhiteway MZhang S
Link:https://pubmed.ncbi.nlm.nih.gov/37307922/
DOI:10.1016/j.addr.2023.114960
Publication:Advanced drug delivery reviews
Keywords:Antifungal drugsAntifungal immunotherapyAntifungal targetsCandidiasisCutaneous infectionSystemic infection
PMID:37307922 Category: Date Added:2023-06-13
Dept Affiliation: BIOLOGY

Description:

Candidiasis is an infection caused by fungi from a Candida species, most commonly Candida albicans. C. albicans is an opportunistic fungal pathogen typically residing on human skin and mucous membranes of the mouth, intestines or vagina. It can cause a wide variety of mucocutaneous barrier and systemic infections; and becomes a severe health problem in HIV/AIDS patients and in individuals who are immunocompromised following chemotherapy, treatment with immunosuppressive agents or after antibiotic-induced dysbiosis. However, the immune mechanism of host resistance to C. albicans infection is not fully understood, there are a limited number of therapeutic antifungal drugs for candidiasis, and these have disadvantages that limit their clinical application. Therefore, it is urgent to uncover the immune mechanisms of the host protecting against candidiasis and to develop new antifungal strategies. This review synthesizes current knowledge of host immune defense mechanisms from cutaneous candidiasis to invasive C. albicans infection and documents promising insights for treating candidiasis through inhibitors of potential antifungal target proteins.





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