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PubMed Publications| Keyword search (4,163 papers available) |  |
"oscillation" Keyword-tagged Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | How vigilance states influence source imaging of physiological brain oscillations: evidence from intracranial EEG | Wei X; Afnan J; Avigdor T; von Ellenrieder N; Delaire É; Royer J; Ho A; Minato E; Schiller K; Jaber K; Wang YL; Moye M; Bernhardt BC; Lina JM; Grova C; Frauscher B; | 41687693 SOH |
| 2 | Climate variability is an important driver of water treatability in a shallow reservoir | Spence DS; Painter KJ; Nazemi A; Venkiteswaran JJ; Baulch HM; | 41166973 ENCS |
| 3 | Neurophysiological effects of targeting sleep spindles with closed-loop auditory stimulation | Jourde HR; Sobral M; Beltrame G; Coffey EBJ; | 40626105 PSYCHOLOGY |
| 4 | Effect of chronic benzodiazepine and benzodiazepine receptor agonist use on sleep architecture and brain oscillations in older adults with chronic insomnia | Barbaux L; Perrault AA; Cross NE; Weiner OM; Es-Sounni M; Pomares FB; Tarelli L; McCarthy M; Maltezos A; Smith D; Gong K; O' Byrne J; Yue V; Desrosiers C; Clerc D; Andriamampionona F; Lussier D; Gilbert S; Tannenbaum C; Gouin JP; Dang-Vu TT; | 40570297 CSBN |
| 5 | Phase-Amplitude Coupling of NREM Sleep Oscillations Shows Between-Night Stability and is Related to Overnight Memory Gains | Cross N; O' Byrne J; Weiner OM; Giraud J; Perrault AA; Dang-Vu TT; | 40214027 PERFORM |
| 6 | Sleep spindles and slow oscillations predict cognition and biomarkers of neurodegeneration in mild to moderate Alzheimer's disease | Páez A; Gillman SO; Dogaheh SB; Carnes A; Dakterzada F; Barbé F; Dang-Vu TT; Ripoll GP; | 39878233 CONCORDIA |
| 7 | Challenges and Approaches in the Study of Neural Entrainment | Duecker K; Doelling KB; Breska A; Coffey EBJ; Sivarao DV; Zoefel B; | 39358026 CONCORDIA |
| 8 | The neurophysiology of closed-loop auditory stimulation in sleep: A magnetoencephalography study | Jourde HR; Merlo R; Brooks M; Rowe M; Coffey EBJ; | 37675803 CONCORDIA |
| 9 | Neurophysiology, Neuropsychology, and Epilepsy, in 2022: Hills We Have Climbed and Hills Ahead. Neurophysiology in epilepsy | Frauscher B; Bénar CG; Engel JJ; Grova C; Jacobs J; Kahane P; Wiebe S; Zjilmans M; Dubeau F; | 37119580 PERFORM |
| 10 | Slow oscillation-spindle cross-frequency coupling predicts overnight declarative memory consolidation in older adults | Oren M Weiner | 37002805 PERFORM |
| 11 | Sigma oscillations protect or reinstate motor memory depending on their temporal coordination with slow waves | Nicolas J; King BR; Levesque D; Lazzouni L; Coffey EBJ; Swinnen S; Doyon J; Carrier J; Albouy G; | 35726850 PSYCHOLOGY |
| 12 | How cerebral cortex protects itself from interictal spikes: The alpha/beta inhibition mechanism | Pellegrino G; Hedrich T; Sziklas V; Lina JM; Grova C; Kobayashi E; | 34002916 PERFORM |
| 13 | Using Models to (Re-)Design Synthetic Circuits. | McCallum G, Potvin-Trottier L | 33405217 BIOLOGY |
| 14 | Cerebellar Cortex 4-12 Hz Oscillations and Unit Phase Relation in the Awake Rat. | Lévesque M; Gao H; Southward C; Langlois JMP; Léna C; Courtemanche R; | 33240052 HKAP |
| 15 | Brain Rhythms During Sleep and Memory Consolidation: Neurobiological Insights. | Marshall L, Cross N, Binder S, Dang-Vu TT | 31799908 PERFORM |
| 16 | State-Dependent Entrainment of Prefrontal Cortex Local Field Potential Activity Following Patterned Stimulation of the Cerebellar Vermis. | Tremblay SA, Chapman CA, Courtemanche R | 31736718 HKAP |
| 17 | Sleep spindles may predict response to cognitive-behavioral therapy for chronic insomnia | Dang-Vu TT; Hatch B; Salimi A; Mograss M; Boucetta S; O' Byrne J; Brandewinder M; Berthomier C; Gouin JP; | 29157588 PERFORM |
| 18 | Cortical reactivations during sleep spindles following declarative learning. | Jegou A, Schabus M, Gosseries O, Dahmen B, Albouy G, Desseilles M, Sterpenich V, Phillips C, Maquet P, Grova C, Dang-Vu TT | 30928690 PERFORM |
| Title: | Sleep spindles and slow oscillations predict cognition and biomarkers of neurodegeneration in mild to moderate Alzheimer's disease | ||||
| Authors: | Páez A, Gillman SO, Dogaheh SB, Carnes A, Dakterzada F, Barbé F, Dang-Vu TT, Ripoll GP | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/39878233/ | ||||
| DOI: | 10.1002/alz.14424 | ||||
| Publication: | Alzheimer s & dementia : the journal of the Alzheimer s Association | ||||
| Keywords: | Alzheimer'; s disease; amyloid beta; biomarkers; cognition; cognitive decline; sleep; sleep spindles; slow oscillations; tau; | ||||
| PMID: | 39878233 | Category: | Date Added: | 2025-01-29 | |
| Dept Affiliation: |
CONCORDIA
1 Sleep, Cognition and Neuroimaging Laboratory, Concordia University, Montreal, Canada. 2 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal (Québec), Canada. 3 Nuffield Department for Primary Care Health Sciences, University of Oxford, Oxford, UK. 4 Unitat de Trastorns Cognitius, Cognition and Behavior Study Group, Hospital Universitari Santa Maria Universitat de Lleida, Lleida, Spain. 5 Translational Research in Respiratory Medicine (TRRM), Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Lleida, Spain. 6 Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic - Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. |
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Description: |
Introduction: Changes in sleep physiology can predate cognitive symptoms by decades in persons with Alzheimer's disease (AD), but it remains unclear which sleep characteristics predict cognitive and neurodegenerative changes after AD onset. Methods: Using data from a prospective cohort of mild to moderate AD (n = 60), we analyzed non-rapid eye movement sleep spindles and slow oscillations (SOs) at baseline and their associations with baseline amyloid beta (Aß) and tau and with cognition from baseline to 3-year follow-up. Results: Higher spindle and SO activity predicted significant changes in Aß and tau at baseline, lower Alzheimer's Disease Assessment Scale Cognitive Subscale (better cognitive performance) score, and higher Mini-Mental State Examination score from baseline to 36 months. Spindles and SOs mediated the effect of phosphorylated tau 181 (pTau181)/Aß42 on cognition, while pTau181/aß42 moderated the effect of spindles and SOs on cognition. Discussion: Our findings demonstrate that spindle and SO activity during sleep constitute predictive and non-invasive biomarkers of neurodegeneration and cognition in AD patients. Highlights: Sleep spindles predict long-term cognitive performance in AD. Sleep spindle and SOs can be predictive, non-invasive biomarkers for AD. Sleep may be one of the most important modifiable risk factors for AD progression. Sleep microarchitecture is a novel therapeutic target for preserving brain heath. Sleep physiology can provide novel therapeutic targets to slow AD progression. |
