Keyword search (4,163 papers available)

"multivariate" Keyword-tagged Publications:

Title Authors PubMed ID
1 A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Yeo BTT; 38659875
HKAP
2 A multidimensional investigation of sleep and biopsychosocialprofiles with associated neural signatures Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Thomas Yeo BT; 38559143
HKAP
3 MVComp toolbox: MultiVariate Comparisons of brain MRI features accounting for common information across metrics Tremblay SA; Alasmar Z; Pirhadi A; Carbonell F; Iturria-Medina Y; Gauthier CJ; Steele CJ; 38463982
SOH
4 Data-Weighted Multivariate Generalized Gaussian Mixture Model: Application to Point Cloud Robust Registration Ge B; Najar F; Bouguila N; 37754943
ENCS
5 Consolidation alters motor sequence-specific distributed representations. Pinsard B, Boutin A, Gabitov E, Lungu O, Benali H, Doyon J 30882348
PERFORM

 

Title:Consolidation alters motor sequence-specific distributed representations.
Authors:Pinsard BBoutin AGabitov ELungu OBenali HDoyon J
Link:https://www.ncbi.nlm.nih.gov/pubmed/30882348?dopt=Abstract
DOI:10.7554/eLife.39324
Publication:eLife
Keywords:functional MRIhumanmemory consolidationmotor sequence learningmultivariate pattern analysisneuroscience
PMID:30882348 Category:Elife Date Added:2019-04-15
Dept Affiliation: PERFORM
1 Laboratoire d'Imagerie Biomédicale, Sorbonne Université, CNRS, INSERM, Paris, France.
2 Functional Neuroimaging Unit, Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, Canada.
3 McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Canada.
4 PERFORM Centre, Concordia University, Montreal, Canada.
5 Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Canada.

Description:

Consolidation alters motor sequence-specific distributed representations.

Elife. 2019 Mar 18;8:

Authors: Pinsard B, Boutin A, Gabitov E, Lungu O, Benali H, Doyon J

Abstract

Functional magnetic resonance imaging (fMRI) studies investigating the acquisition of sequential motor skills in humans have revealed learning-related functional reorganizations of the cortico-striatal and cortico-cerebellar motor systems accompanied with an initial hippocampal contribution. Yet, the functional significance of these activity-level changes remains ambiguous as they convey the evolution of both sequence-specific knowledge and unspecific task ability. Moreover, these changes do not specifically assess the occurrence of learning-related plasticity. To address these issues, we investigated local circuits tuning to sequence-specific information using multivariate distances between patterns evoked by consolidated or newly acquired motor sequences production. The results reveal that representations in dorsolateral striatum, prefrontal and secondary motor cortices are greater when executing consolidated sequences than untrained ones. By contrast, sequence representations in the hippocampus and dorsomedial striatum becomes less engaged. Our findings show, for the first time in humans, that complementary sequence-specific motor representations evolve distinctively during critical phases of skill acquisition and consolidation.

PMID: 30882348 [PubMed - in process]





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