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PubMed Publications| Keyword search (4,164 papers available) |  |
"insulin sensitivity" Keyword-tagged Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Natural history and determinants of dysglycemia in Canadian children with parental obesity from ages 8-10 to 15-17 years: The QUALITY cohort | Soren Harnois-Leblanc | 35023257 PERFORM |
| 2 | Body Mass Index Z Score vs Weight-for-Length Z Score in Infancy and Cardiometabolic Outcomes at Age 8-10 Years | Roberge JB; Harnois-Leblanc S; McNealis V; van Hulst A; Barnett TA; Kakinami L; Paradis G; Henderson M; | 34302856 PERFORM |
| Title: | Body Mass Index Z Score vs Weight-for-Length Z Score in Infancy and Cardiometabolic Outcomes at Age 8-10 Years | ||||
| Authors: | Roberge JB, Harnois-Leblanc S, McNealis V, van Hulst A, Barnett TA, Kakinami L, Paradis G, Henderson M | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/34302856/ | ||||
| DOI: | 10.1016/j.jpeds.2021.07.046 | ||||
| Publication: | The Journal of pediatrics | ||||
| Keywords: | adiposity; android-to-gynoid ratio; blood pressure; cardiometabolic health; childhood obesity; childhood overweight; insulin secretion; insulin sensitivity; lipid profile; waist circumference; whole body fat; | ||||
| PMID: | 34302856 | Category: | Date Added: | 2021-07-25 | |
| Dept Affiliation: |
PERFORM
1 CHU Sainte-Justine Research Centre, University of Montréal, Montréal, Canada; Department of Pediatrics, Faculty of Medicine, University of Montréal, Montréal, Canada. 2 CHU Sainte-Justine Research Centre, University of Montréal, Montréal, Canada; School of Public Health, University of Montréal, Montréal, Canada. 3 CHU Sainte-Justine Research Centre, University of Montréal, Montréal, Canada. 4 Ingram School of Nursing, McGill University, Montréal, Canada. 5 CHU Sainte-Justine Research Centre, University of Montréal, Montréal, Canada; Department of Family Medicine, McGill University, Montréal, Canada. 6 Department of Mathematics and Statistics, McGill University, Montréal, Canada; PERFORM Centre, Concordia University, Montréal, Canada. 7 Department of Epidemiology, Biostatistics and Occupational Health, Montréal, Canada. 8 CHU Sainte-Justine Research Centre, University of Montréal, Montréal, Canada; Department of Pediatrics, Faculty of Medicine, University of Montréal, Montréal, Canada; School of Public Health, University of Montréal, Montréal, Canada. Electronic address: melanie.henderson.hsj@gmail.com. |
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Description: |
Objectives: To confirm that World Health Organization weight-for-length z scores (zWFL) and World Health Organization body mass index z scores (zBMI) in infancy are associated with adiposity and cardiometabolic measures at 8-10 years old and to compare the predictive ability of the 2 methods. Study design: zWFL and zBMI at 6, 12, and 18 months of age were computed using data extracted from health booklets, among participants in the Québec Adipose and Lifestyle InvesTigation in Youth prospective cohort (n = 464). Outcome measures at 8-10 years included adiposity, lipid profile, blood pressure, and insulin dynamics. The relationships between zWFL, zBMI, and each outcome were estimated using multivariable linear regression models. Outcome prediction at 8-10 years was compared between the 2 methods using eta-squared and the Lin concordance correlation coefficient. Results: zWFL and zBMI were associated with all measures of adiposity at 8-10 years. Associations with other cardiometabolic measures were less consistent. For both zWFL and zBMI across infancy, eta-squared were highly similar and the Lin coefficients were markedly high (=0.991) for all outcomes. Conclusions: There was no evidence that zBMI and zWFL in infancy differed in their ability to predict adiposity and cardiometabolic measures in childhood. This lends support to the sole use of zBMI for growth monitoring and screening of overweight and obesity from birth to 18 years. Trial registration: ClinicalTrials.gov: NCT03356262. |
