Keyword search (4,163 papers available)

"enzyme" Keyword-tagged Publications:

Title Authors PubMed ID
1 Fortifying the Rasamsonia emersonii secretome with recombinant cellobiohydrolase (GH7) for efficient biomass saccharification Raheja Y; Singh V; Gaur VK; Sharma G; Tsang A; Chadha BS; 40622460
GENOMICS
2 The enterobactin biosynthetic intermediate 2,3-dihydroxybenzoic acid is a competitive inhibitor of the Escherichia coli isochorismatase EntB Bin X; Pawelek PD; 40400396
CHEMBIOCHEM
3 All-Inclusive Sensing Tablet with Integrated Passive Mixer for Ultraviscous Solutions Safiabadi Tali SH; Al-Kassawneh M; Mansouri M; Sadiq Z; Jahanshahi-Anbuhi S; 40327804
ENCS
4 The degradation of polylactic acid face mask components in different environments Lyu L; Bagchi M; Ng KTW; Markoglou N; Chowdhury R; An C; Chen Z; Yang X; 39378804
ENCS
5 Expansion of Auxiliary Activity Family 5 sequence space via biochemical characterization of six new copper radical oxidases Fong JK; Mathieu Y; Vo MT; Bellemare A; Tsang A; Brumer H; 38953370
CSFG
6 Non-invasive paper-based sensors containing rare-earth-doped nanoparticles for the detection of D-glucose López-Peña G; Ortiz-Mansilla E; Arranz A; Bogdan N; Manso-Silván M; Martín Rodríguez E; 38729020
CHEMBIOCHEM
7 Functional screening pipeline to uncover laccase-like multicopper oxidase enzymes that transform industrial lignins Sharan AA; Bellemare A; DiFalco M; Tsang A; Vuong TV; Edwards EA; Master ER; 38000639
CSFG
8 Identification of a Conserved Transcriptional Activator-Repressor Module Controlling the Expression of Genes Involved in Tannic Acid Degradation and Gallic Acid Utilization in Aspergillus niger Arentshorst M; Falco MD; Moisan MC; Reid ID; Spaapen TOM; van Dam J; Demirci E; Powlowski J; Punt PJ; Tsang A; Ram AFJ; 37744122
CSFG
9 Functional analysis of the protocatechuate branch of the β-ketoadipate pathway in Aspergillus niger Sgro M; Chow N; Olyaei F; Arentshorst M; Geoffrion N; Ram AFJ; Powlowski J; Tsang A; 37399977
BIOLOGY
10 Identification of Genes Involved in the Degradation of Lignocellulose Using Comparative Transcriptomics Gruninger RJ; Tsang A; McAllister TA; 37149538
CSFG
11 Vitamin B5, a Coenzyme A precursor, rescues TANGO2 deficiency disease-associated defects in Drosophila and human cells Asadi P; Milev MP; Saint-Dic D; Gamberi C; Sacher M; 36502486
BIOLOGY
12 Engineering the Enzyme Toolbox to Tailor Glycosylation in Small Molecule Natural Products and Protein Biologics Ouadhi S; López DMV; Mohideen FI; Kwan DH; 36444941
ENCS
13 Evidence for ligninolytic activity of the ascomycete fungus Podospora anserina. van Erven G, Kleijn AF, Patyshakuliyeva A, Di Falco M, Tsang A, de Vries RP, van Berkel WJH, Kabel MA 32322305
CSFG
14 Effect and ameliorative mechanisms of polyoxometalates on the denitrification under sulfonamide antibiotics stress. Guo H, Chen Z, Lu C, Guo J, Li H, Song Y, Han Y, Hou Y 32145698
ENCS
15 Angiotensin-I-Converting Enzyme Inhibitory Activity of Coumarins from Angelica decursiva. Ali MY, Seong SH, Jung HA, Choi JS 31683604
CHEMBIOCHEM
16 Umbelliferone derivatives exert neuroprotective effects by inhibiting monoamine oxidase A, self-amyloidβ aggregation, and lipid peroxidation. Seong SH, Ali MY, Jung HA, Choi JS 31557622
CHEMBIOCHEM
17 Enzymes of early-diverging, zoosporic fungi. Lange L, Barrett K, Pilgaard B, Gleason F, Tsang A 31309267
CSFG
18 Effects of a recombinant fibrolytic enzyme on fiber digestion, ruminal fermentation, nitrogen balance and total tract digestibility of heifers fed a high forage diet. Ran T, Saleem AM, Shen Y, Ribeiro GO, Beauchemin KA, Tsang A, Yang W, McAllister TA 31251799
CSFG
19 Transcriptome and exoproteome analysis of utilization of plant-derived biomass by Myceliophthora thermophila. Kolbusz MA, Di Falco M, Ishmael N, Marqueteau S, Moisan MC, Baptista CDS, Powlowski J, Tsang A 24881579
BIOLOGY
20 Closely related fungi employ diverse enzymatic strategies to degrade plant biomass. Benoit I, Culleton H, Zhou M, DiFalco M, Aguilar-Osorio G, Battaglia E, Bouzid O, Brouwer CPJM, El-Bushari HBO, Coutinho PM, Gruben BS, Hildén KS, Houbraken J, Barboza LAJ, Levasseur A, Majoor E, Mäkelä MR, Narang HM, Trejo-Aguilar B, van den Brink J, vanKuyk PA, Wiebenga A, McKie V, McCleary B, Tsang A, Henrissat B, de Vries RP 26236396
CSFG
21 Identification of Genes Involved in the Degradation of Lignocellulose Using Comparative Transcriptomics. Gruninger RJ, Reid I, Forster RJ, Tsang A, McAllister TA 28417376
CSFG
22 Discovery and characterization of family 39 glycoside hydrolases from rumen anaerobic fungi with polyspecific activity on rare arabinosyl substrates. Jones DR, Uddin MS, Gruninger RJ, Pham TTM, Thomas D, Boraston AB, Briggs J, Pluvinage B, McAllister TA, Forster RJ, Tsang A, Selinger LB, Abbott DW 28588026
CSFG
23 Structure-Guided Directed Evolution of Glycosidases: A Case Study in Engineering a Blood Group Antigen-Cleaving Enzyme. Kwan DH 28935105
CSFG
24 Identification of novel enzymes to enhance the ruminal digestion of barley straw Badhan A; Ribeiro GO; Jones DR; Wang Y; Abbott DW; Di Falco M; Tsang A; McAllister TA; 29621684
CSFG
25 Saccharification efficiencies of multi-enzyme complexes produced by aerobic fungi. Badhan A, Huang J, Wang Y, Abbott DW, Di Falco M, Tsang A, McAllister T 29803771
CSFG
26 New recombinant fibrolytic enzymes for improved in vitro ruminal fiber degradability of barley straw. Ribeiro GO, Badhan A, Huang J, Beauchemin KA, Yang W, Wang Y, Tsang A, McAllister TA 30053012
CSFG
27 Application of Transcriptomics to Compare the Carbohydrate Active Enzymes That Are Expressed by Diverse Genera of Anaerobic Fungi to Degrade Plant Cell Wall Carbohydrates. Gruninger RJ, Nguyen TTM, Reid ID, Yanke JL, Wang P, Abbott DW, Tsang A, McAllister T 30061875
CSFG
28 The obligate alkalophilic soda-lake fungus Sodiomyces alkalinus has shifted to a protein diet. Grum-Grzhimaylo AA, Falkoski DL, van den Heuvel J, Valero-Jiménez CA, Min B, Choi IG, Lipzen A, Daum CG, Aanen DK, Tsang A, Henrissat B, Bilanenko EN, de Vries RP, van Kan JAL, Grigoriev IV, Debets AJM 30368956
CSFG
29 Thermostable xylanases from thermophilic fungi and bacteria: Current perspective. Chadha BS, Kaur B, Basotra N, Tsang A, Pandey A 30679061
CSFG

 

Title:Angiotensin-I-Converting Enzyme Inhibitory Activity of Coumarins from Angelica decursiva.
Authors:Ali MYSeong SHJung HAChoi JS
Link:https://www.ncbi.nlm.nih.gov/pubmed/31683604?dopt=Abstract
DOI:10.3390/molecules24213937
Publication:Molecules (Basel, Switzerland)
Keywords:Angelica decursivaangiotensin-I-converting enzymeantihypertensioncoumarinsmolecular docking
PMID:31683604 Category:Molecules Date Added:2019-11-07
Dept Affiliation: CHEMBIOCHEM
1 Department of Food and Life Science, Pukyong National University, Busan 48513, Korea. yousufbge@gmail.com.
2 Department of Chemistry and Biochemistry, Concordia University, Montreal, QC H4B 1R6, Canada. yousufbge@gmail.com.
3 Department of Biology, Faculty of Arts and Science, Concordia University, 7141 Sherbrooke St. W., Montreal, QC H4B 1R6, Canada. yousufbge@gmail.com.
4 Centre for Structural and Functional Genomic, Department of Biology, Faculty of Arts and Science, Concordia University, 7141 Sherbrooke St. W., Montreal, QC H4B 1R6, Canada. yousufbge@gmail.com.
5 Department of Food and Life Science, Pukyong National University, Busan 48513, Korea. seongsuhui@naver.com.
6 Department of Food Science and Human Nutrition, Jeonbuk National University, Jeonju 54896, Korea. jungha@jbnu.ac.kr.
7 Department of Food and Life Science, Pukyong National University, Busan 48513, Korea. choijs@pknu.ac.kr.

Description:

Angiotensin-I-Converting Enzyme Inhibitory Activity of Coumarins from Angelica decursiva.

Molecules. 2019 Oct 31;24(21):

Authors: Ali MY, Seong SH, Jung HA, Choi JS

Abstract

The bioactivity of ten traditional Korean Angelica species were screened by angiotensin-converting enzyme (ACE) assay in vitro. Among the crude extracts, the methanol extract of Angelica decursiva whole plants exhibited potent inhibitory effects against ACE. In addition, the ACE inhibitory activity of coumarins 1-5, 8-18 was evaluated, along with two phenolic acids (6, 7) obtained from A. decursiva. Among profound coumarins, 11-18 were determined to manifest marked inhibitory activity against ACE with IC50 values of 4.68-20.04 µM. Compounds 12, 13, and 15 displayed competitive inhibition against ACE. Molecular docking studies confirmed that coumarins inhibited ACE via many hydrogen bond and hydrophobic interactions with catalytic residues and zinc ion of C- and N-domain ACE that blocked the catalytic activity of ACE. The results derived from these computational and in vitro experiments give additional scientific support to the anecdotal use of A. decursiva in traditional medicine to treat cardiovascular diseases such as hypertension.

PMID: 31683604 [PubMed - in process]





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