Keyword search (4,163 papers available)

"dopamine" Keyword-tagged Publications:

Title Authors PubMed ID
1 Dopamine inhibits excitatory synaptic responses in layer I of the rat parasubiculum Carter F; Hobishi H; Chapman CA; 40818632
PSYCHOLOGY
2 Insights into dietary phytochemicals targeting Parkinson's disease key genes and pathways: A network pharmacology approach Sasikumar DSN; Thiruselvam P; Sundararajan V; Ravindran R; Gunasekaran S; Madathil D; Kaliamurthi S; Peslherbe GH; Selvaraj G; Sudhakaran SL; 38460310
CHEMBIOCHEM
3 Dopamine dysregulation in Parkinson's disease flattens the pleasurable urge to move to musical rhythms Pando-Naude V; Matthews TE; Højlund A; Jakobsen S; Østergaard K; Johnsen E; Garza-Villarreal EA; Witek MAG; Penhune V; Vuust P; 37724707
PSYCHOLOGY
4 Behavioral, Neural, and Molecular Mechanisms of Conditioned Mate Preference: The Role of Opioids and First Experiences of Sexual Reward Gonzalo R Quintana 36012194
PSYCHOLOGY
5 The Convergence Model of Brain Reward Circuitry: Implications for Relief of Treatment-Resistant Depression by Deep-Brain Stimulation of the Medial Forebrain Bundle Pallikaras V; Shizgal P; 35431828
PSYCHOLOGY
6 The rodent medial prefrontal cortex and associated circuits in orchestrating adaptive behavior under variable demands Howland JG; Ito R; Lapish CC; Villaruel FR; 35131398
PSYCHOLOGY
7 The trade-off between pulse duration and power in optical excitation of midbrain dopamine neurons approximates Bloch's law Pallikaras V; Carter F; Velazquez-Martinez DN; Arvanitogiannis A; Shizgal P; 34864162
PSYCHOLOGY
8 Anxiety-like behavior in female mice is modulated by STAT3 signaling in midbrain dopamine neurons Fernandes MF; Lau D; Sharma S; Fulton S; 33872705
CSBN
9 Neural substrates of appetitive and aversive prediction error. Iordanova MD, Yau JO, McDannald MA, Corbit LH 33453307
CSBN
10 Cue-Evoked Dopamine Neuron Activity Helps Maintain but Does Not Encode Expected Value. Mendoza JA, Lafferty CK, Yang AK, Britt JP 31693885
CSBN
11 High estrogen and chronic haloperidol lead to greater amphetamine-induced BOLD activation in awake, amphetamine-sensitized female rats. Madularu D, Kulkarni P, Yee JR, Kenkel WM, Shams WM, Ferris CF, Brake WG 27154458
CSBN
12 Ventral Midbrain NMDA Receptor Blockade: From Enhanced Reward and Dopamine Inactivation. Hernandez G, Cossette MP, Shizgal P, Rompré PP 27616984
PSYCHOLOGY
13 Neurotensin in the nucleus accumbens reverses dopamine supersensitivity evoked by antipsychotic treatment. Servonnet A, Minogianis EA, Bouchard C, Bédard AM, Lévesque D, Rompré PP, Samaha AN 28522313
CSBN
14 Microbial Factories for the Production of Benzylisoquinoline Alkaloids. Narcross L, Fossati E, Bourgeois L, Dueber JE, Martin VJJ 26775900
BIOLOGY
15 Posterior dopamine D2/3 receptors and brain network functional connectivity. Nagano-Saito A, Lissemore JI, Gravel P, Leyton M, Carbonell F, Benkelfat C 28700819
PERFORM

 

Title:Microbial Factories for the Production of Benzylisoquinoline Alkaloids.
Authors:Narcross LFossati EBourgeois LDueber JEMartin VJJ
Link:https://www.ncbi.nlm.nih.gov/pubmed/26775900?dopt=Abstract
DOI:10.1016/j.tibtech.2015.12.005
Publication:Trends in biotechnology
Keywords:aromatic amino acidsbenzylisoquinoline alkaloidsbiosecuritydopaminemicrobial synthesismorphinans
PMID:26775900 Category:Trends Biotechnol Date Added:2019-06-07
Dept Affiliation: BIOLOGY
1 Department of Biology, Concordia University, Montréal, Québec H4B 1R6, Canada; Centre for Structural and Functional Genomics, Concordia University, Montréal, Québec H4B 1R6, Canada.
2 Department of Bioengineering, University of California, Berkeley, Berkeley, CA 94704, USA.
3 Department of Biology, Concordia University, Montréal, Québec H4B 1R6, Canada; Centre for Structural and Functional Genomics, Concordia University, Montréal, Québec H4B 1R6, Canada. Electronic address: vincent.martin@concordia.ca.

Description:

Microbial Factories for the Production of Benzylisoquinoline Alkaloids.

Trends Biotechnol. 2016 Mar;34(3):228-241

Authors: Narcross L, Fossati E, Bourgeois L, Dueber JE, Martin VJJ

Abstract

Benzylisoquinoline alkaloids (BIAs) are a family of ~2500 alkaloids with both potential and realized pharmaceutical value, including most notably the opiates such as codeine and morphine. Only a few BIAs accumulate readily in plants, which limits the pharmaceutical potential of the family. Shifting BIA production to microbial sources could provide a scalable and flexible source of these compounds in the future. This review details the current status of microbial BIA synthesis and derivatization, including rapid developments in the past 6 months culminating in the synthesis of opioids from glucose in a microbial host.

PMID: 26775900 [PubMed - indexed for MEDLINE]





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