Keyword search (4,163 papers available)

"dipole" Keyword-tagged Publications:

Title Authors PubMed ID
1 Wideband Dual-Polarized PRGW Antenna Array with High Isolation for Millimeter-Wave IoT Applications Mousavirazi Z; Ali MMM; Sebak AR; Denidni TA; 40968922
ENCS
2 Electric Field-Induced Nano-Assembly Formation: First Evidence of Silicon Superclusters with a Giant Permanent Dipole Moment Jardali F; Tran J; Liège F; Florea I; Leulmi ME; Vach H; 37570492
CERMM
3 Design and Development of a Wideband Planar Yagi Antenna Using Tightly Coupled Directive Element. Ashraf MA; Jamil K; Telba A; Alzabidi MA; Sebak AR; 33143035
ENCS
4 Influence of Head Tissue Conductivity Uncertainties on EEG Dipole Reconstruction. Vorwerk J, Aydin Ü, Wolters CH, Butson CR 31231178
PERFORM
5 Clinical yield of magnetoencephalography distributed source imaging in epilepsy: A comparison with equivalent current dipole method. Pellegrino G, Hedrich T, Chowdhury RA, Hall JA, Dubeau F, Lina JM, Kobayashi E, Grova C 29024165
PERFORM

 

Title:Clinical yield of magnetoencephalography distributed source imaging in epilepsy: A comparison with equivalent current dipole method.
Authors:Pellegrino G,  Hedrich T,  Chowdhury RA,  Hall JA,  Dubeau F,  Lina JM,  Kobayashi E,  Grova C
Link:https://www.ncbi.nlm.nih.gov/pubmed/29024165?dopt=Abstract
DOI:10.1002/hbm.23837
Publication:Human brain mapping
Keywords:MEG;  dipole;  distributed source;  interictal epileptiform discharges;  magnetic source imaging;  presurgical evaluation;  source localization;  spike;  surgery; 
PMID:29024165 Category:Hum Brain Mapp Date Added:2019-06-04
Dept Affiliation: PERFORM
1 Multimodal Functional Imaging Lab, Biomedical Engineering Department, McGill University, Montreal, Quebec, Canada.
2 Neurology and Neurosurgery Department, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
3 IRCCS Fondazione San Camillo Hospital, Venice, Italy.
4 Departement de Génie Electrique, Ecole de Technologie Supérieure, Montreal, Quebec, Canada.
5 Centre De Recherches En Mathématiques, Montreal, Quebec, Canada.
6 Centre D'études Avancées En Médecine Du Sommeil, Centre De Recherche De L'hôpital Sacré-Coeur De Montréal, Montreal, Quebec, Canada.
7 Physics Department and PERFORM Centre, Concordia University, Montreal, Quebec, Canada.

Description:

Clinical yield of magnetoencephalography distributed source imaging in epilepsy: A comparison with equivalent current dipole method.

Hum Brain Mapp. 2018 01;39(1):218-231

Authors: Pellegrino G, Hedrich T, Chowdhury RA, Hall JA, Dubeau F, Lina JM, Kobayashi E, Grova C

Abstract

OBJECTIVE: Source localization of interictal epileptic discharges (IEDs) is clinically useful in the presurgical workup of epilepsy patients. It is usually obtained by equivalent current dipole (ECD) which localizes a point source and is the only inverse solution approved by clinical guidelines. In contrast, magnetic source imaging using distributed methods (dMSI) provides maps of the location and the extent of the generators, but its yield has not been clinically validated. We systematically compared ECD versus dMSI performed using coherent Maximum Entropy on the Mean (cMEM), a method sensitive to the spatial extent of the generators.

METHODS: 340 source localizations of IEDs derived from 49 focal epilepsy patients with foci well-defined through intracranial EEG, MRI lesions, and surgery were analyzed. The comparison was based on the assessment of the sublobar concordance with the focus and of the distance between the source and the focus.

RESULTS: dMSI sublobar concordance was significantly higher than ECD (81% vs 69%, P?<?0.001), especially for extratemporal lobe sources (dMSI?=?84%; ECD?=?67%, P?<?0.001) and for seizure free patients (dMSI?=?83%; ECD?=?70%, P?<?0.001). The median distance from the focus was 4.88 mm for ECD and 3.44 mm for dMSI (P?<?0.001). ECD dipoles were often wrongly localized in deep brain regions.

CONCLUSIONS: dMSI using cMEM exhibited better accuracy. dMSI also offered the advantage of recovering more realistic maps of the generator, which could be exploited for neuronavigation aimed at targeting invasive EEG and surgical resection. Therefore, dMSI may be preferred to ECD in clinical practice. Hum Brain Mapp 39:218-231, 2018. © 2017 Wiley Periodicals, Inc.

PMID: 29024165 [PubMed - indexed for MEDLINE]




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