Keyword search (4,163 papers available)

"cerebellum" Keyword-tagged Publications:

Title Authors PubMed ID
1 Pontine Functional Connectivity Gradients Rousseau PN; Bazin PL; Steele CJ; 41420671
SOH
2 Multiscale gradients of corticopontine structural connectivity Rousseau PN; Bazin PL; Steele CJ; 40355513
SOH
3 Patterns of Cerebellar-Cortical Structural Covariance Mirror Anatomical Connectivity of Sensorimotor and Cognitive Networks Alasmar Z; Chakravarty MM; Penhune VB; Steele CJ; 39791308
SOH
4 Intrinsic structural covariation links cerebellum subregions to the cerebral cortex Wang Z; Diedrichsen J; Saltoun K; Steele C; Arnold-Anteraper SR; Yeo BTT; Schmahmann JD; Bzdok D; 39052236
PSYCHOLOGY
5 Mapping pontocerebellar connectivity with diffusion MRI Rousseau PN; Chakravarty MM; Steele CJ; 36252913
PERFORM
6 White matter correlates of sensorimotor synchronization in persistent developmental stuttering Jossinger S; Sares A; Zislis A; Sury D; Gracco V; Ben-Shachar M; 34856426
PSYCHOLOGY
7 Early musical training shapes cortico-cerebellar structural covariation Shenker JJ; Steele CJ; Chakravarty MM; Zatorre RJ; Penhune VB; 34657166
PSYCHOLOGY
8 TRAPPC11-related muscular dystrophy with hypoglycosylation of alpha-dystroglycan in skeletal muscle and brain Munot P; McCrea N; Torelli S; Manzur A; Sewry C; Chambers D; Feng L; Ala P; Zaharieva I; Ragge N; Roper H; Marton T; Cox P; Milev MP; Liang WC; Maruyama S; Nishino I; Sacher M; Phadke R; Muntoni F; 34648194
BIOLOGY
9 Cerebellar Cortex 4-12 Hz Oscillations and Unit Phase Relation in the Awake Rat. Lévesque M; Gao H; Southward C; Langlois JMP; Léna C; Courtemanche R; 33240052
HKAP
10 Inhibitory potentials of Cymbopogon citratus oil against aluminium-induced behavioral deficits and neuropathology in rats. Temitayo GI, Olawande B, Emmanuel YO, Timothy AT, Kehinde O, Susan LF, Ezra L, Joseph OO 32839358
PSYCHOLOGY
11 State-Dependent Entrainment of Prefrontal Cortex Local Field Potential Activity Following Patterned Stimulation of the Cerebellar Vermis. Tremblay SA, Chapman CA, Courtemanche R 31736718
HKAP

 

Title:Inhibitory potentials of Cymbopogon citratus oil against aluminium-induced behavioral deficits and neuropathology in rats.
Authors:Temitayo GI,  Olawande B,  Emmanuel YO,  Timothy AT,  Kehinde O,  Susan LF,  Ezra L,  Joseph OO
Link:https://www.ncbi.nlm.nih.gov/pubmed/32839358
DOI:10.5115/acb.20.099
Publication:Anatomy & cell biology
Keywords:Cerebellum;  Cymbopogon;  Inflammation;  Oxidative stress; 
PMID:32839358 Category:Anat Cell Biol Date Added:2020-08-26
Dept Affiliation: PSYCHOLOGY
1 Division of Neurobiology, Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.
2 Division of Neurobiology, Department of Anatomy, Faculty of Basic Medical Sciences, Adeleke University, Ede, Nigeria.
3 Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University Montreal, Montreal, Quebec, Canada.

Description:

Inhibitory potentials of Cymbopogon citratus oil against aluminium-induced behavioral deficits and neuropathology in rats.

Anat Cell Biol. 2020 Aug 25; :

Authors: Temitayo GI, Olawande B, Emmanuel YO, Timothy AT, Kehinde O, Susan LF, Ezra L, Joseph OO

Abstract

Cymbopogon citratus is a tropical phytomedicinal plant that is widely known for its hypoglycemic, hypolipidemic, anxiolytic, sedative, antioxidative and anti-inflammatory properties. In this study, we have examined the neuroprotective effects of the essential oil (ESO) of Cymbopogon citratus, following aluminum chloride (AlCl3)-induced neurotoxicity within the cerebellum of Wistar rats. A total of 40 adult male Wistar rats were assigned into five groups and treated orally as follows: A-phosphate-buffered saline (1 ml daily for 15 days); B-ESO (50 mg/kg daily for 15 days); C-AlCl3 (100 mg/kg daily for 15 days); D-AlCl3 then ESO (100 mg/kg AlCl3 daily for 15 days followed by 50 mg/kg ESO daily for subsequent 15 days); E-ESO then AlCl3 (50 mg/kg ESO daily for 15 days followed by 100 mg/kg AlCl3 daily for following 15 days). To address our questions, we observed the locomotion and exploratory behavior of the rats in the open field apparatus and subsequently evaluated cerebellar oxidative redox parameters, neural bioenergetics, acetylcholinesterase levels, transferrin receptor protein, and total protein profiles by biochemical assays. Furthermore, we investigated cerebellar histomorphology and Nissl profile by H& E and Cresyl violet Nissl staining procedures. ESO treatment markedly attenuated deficits in exploratory activities and rearing behavior following AlCl3 toxicity, indicating its anxiolytic potentials. Additionally, AlCl3 evokedincrease in malondialdehyde and nitric oxide levels, as well as repressed cerebellar catalase, glutathione peroxidase, and superoxide dismutase profiles were normalised to baseline levels by ESO treatment. Treatment with ESO, ergo, exhibits substantial neuroprotective and modulatory potentials in response to AlCl3 toxicity.

PMID: 32839358 [PubMed - as supplied by publisher]




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