PERFORM Publications

Keyword search (4,164 papers available)

Title		Authors	PubMed ID
1	Recruitment dynamics of juvenile salmonids: Comparisons among populations and with classic case studies	Matte JO; Fraser DJ; Grant JWA;	38599588 BIOLOGY
2	Discovery of an adjuvant that resensitizes polymyxin B-resistant bacteria	Mahdavi M; Findlay BL;	38096681 BIOLOGY
3	Understanding Fluconazole Tolerance in Candida albicans: Implications for Effective Treatment of Candidiasis and Combating Invasive Fungal Infections	Feng Y; Lu H; Whiteway M; Jiang Y;	37918789 BIOLOGY
4	Cross-collection latent Beta-Liouville allocation model training with privacy protection and applications	Luo Z; Amayri M; Fan W; Bouguila N;	36685642 ENCS
5	Stable Cavitation-Mediated Delivery of miR-126 to Endothelial Cells	He S; Singh D; Yusefi H; Helfield B;	36559150 BIOLOGY
6	A Small Molecule Inhibitor of Erg251 Makes Fluconazole Fungicidal by Inhibiting the Synthesis of the 14α-Methylsterols	Lu H; Li W; Whiteway M; Wang H; Zhu S; Ji Z; Feng Y; Yan L; Fang T; Li L; Ni T; Zhang X; Lv Q; Ding Z; Qiu L; Zhang D; Jiang Y;	36475771 BIOLOGY
7	Pattern and Visual Prognostic Factors of Behcet's Uveitis in Northwest Iran	Alizadeh Ghavidel L; Bagheri M; Mousavi F; Rezaei L; Hazeri S; Hashemi HS;	35765637 BIOLOGY
8	Removal of SARS-CoV-2 using UV+Filter in built environment: simulation/evaluation by utilizing validated numerical method	Feng Z; Cao SJ; Haghighat F;	34367884 ENCS
9	Drug discovery and chemical probing in Drosophila.	Millet-Boureima C, Selber-Hnatiw S, Gamberi C	32551911 BIOLOGY
10	Early Life History of Coreoperca herzi in Han River, Korea.	Park JM, Jeon HB, Suk HY, Cho SJ, Han KH	32411919 BIOLOGY
11	Population variation in density-dependent growth, mortality and their trade-off in a stream fish.	Matte JM, Fraser DJ, Grant JWA	31642512 BIOLOGY

Title:	Drug discovery and chemical probing in Drosophila.
Authors:	Millet-Boureima C, Selber-Hnatiw S, Gamberi C
Link:	https://www.ncbi.nlm.nih.gov/pubmed/32551911?dopt=Abstract
DOI:	10.1139/gen-2020-0037
Publication:	Genome
Keywords:	Drosophila; criblage de composé; s; drug discovery; drug screens; dé; couverte de mé; dicaments; maladies orphelines; modè; les animaux; orphan disease; pathway probing; polycystic kidney disease; polykystose ré; nale; sondage des sentiers; whole-animal models;
PMID:	32551911	Category:	Genome	Date Added:	2020-06-20
Dept Affiliation:	BIOLOGY 1 Biology Department, Concordia University, Montreal, QC H4B 1R6, Canada.

Description:

Drug discovery and chemical probing in Drosophila.

Genome. 2020 Jun 18;:

Authors: Millet-Boureima C, Selber-Hnatiw S, Gamberi C

Abstract

Flies are increasingly utilized in drug discovery and chemical probing in vivo, which are novel technologies complementary to genetic probing in fundamental biological studies. Excellent genetic conservation, small size, short generation time and over one hundred years of genetics make Drosophila an attractive model for rapid assay readout and use of analytical amounts of compound, enabling the experimental iterations needed in early drug development at a fraction of time and costs. Here, we describe an effective drug-testing pipeline using adult flies that can be easily implemented to study several disease models and different genotypes to discover novel molecular insight, probes, quality lead compounds, and develop novel prototype drugs.

PMID: 32551911 [PubMed - as supplied by publisher]

BookR: School of Health Core Facilities Booking

"UV" Keyword-tagged Publications:

Search Publications

No results