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PubMed Publications| Keyword search (4,164 papers available) |  |
"Toxicity" Keyword-tagged Publications:
| Title: | Effects of delayed post-polymerization on physical, chemical, and biological properties of a 3D printing interim resin | ||||
| Authors: | Choi Y, Comeau P, Lim BS, Manso AP, Chung SH | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/41152035/ | ||||
| DOI: | 10.1016/j.dental.2025.10.005 | ||||
| Publication: | Dental materials : official publication of the Academy of Dental Materials | ||||
| Keywords: | 3D printing resin; Additive manufacturing; Color; Cytotoxicity; Degree of conversion; Flexural strength; Inflammatory response; Post-polymerization; Time delay; | ||||
| PMID: | 41152035 | Category: | Date Added: | 2025-10-29 | |
| Dept Affiliation: |
ENCS
1 Department of Dental Biomaterials Science, Dental Research Institute, School of Dentistry, Seoul National University, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea. 2 Department of Oral Health Sciences, Division of Restorative Dentistry, Faculty of Dentistry, The University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC V6T 1Z3, Canada; Advancing Multifunctional Dental Biomaterials Research Excellence Cluster, The University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC V6T 1Z3, Canada; Department of Chemical and Materials Engineering, Gina Cody School of Engineering and Computer Science, Concordia University, 1455 De Maisonneuve Blvd. W., Montreal, QC H3G 1M8, Canada. 3 Department of Oral Health Sciences, Division of Restorative Dentistry, Faculty of Dentistry, The University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC V6T 1Z3, Canada; Advancing Multifunctional Dental Biomaterials Research Excellence Cluster, The University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC V6T 1Z3, Canada. Electronic address: amanso@dentistry.ubc.ca. 4 Department of Dental Biomaterials Science, Dental Research Institute, School of Dentistry, Seoul National University, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea. Electronic address: den533@snu.ac.kr. |
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Description: |
Objectives: This study evaluated the effects of delayed post-polymerization on color, degree of conversion (DC), flexural strength (FS), and cellular response of a 3D-printed dental interim resin. Methods: Specimens were divided into six groups based on delays of 0 h, 2 h, 4 h, 6 h, 8 h, and 10 h before post-polymerization. Color was characterized using a spectrophotometer (n = 10), DC (n = 10) with FTIR-ATR, and FS (n = 10) with a universal testing machine. Cellular response (n = 30) was assessed through cell viability and pro-inflammatory gene expression of the gingival fibroblast cell line (L929) and human monocytic cell line (THP-1). Results: Delayed post-polymerization significantly affected color (L* and b*; both P < 0.001,) and color difference (P = 0.016). L* values at 6 h, 8 h, and 10 h significantly decreased compared to 0 h (P < 0.001), while b* values showed a significant decrease in all groups. (P < 0.001). No significant difference was found in a* (P = 0.417) or translucency (P = 0.394). DC significantly decreased at 8 h and 10 h (P < 0.05). There was no significant difference in FS. Cytotoxicity and pro-inflammatory gene expression (IL-6 and TNF-a) were not significantly affected by time delays. Significance: Within the limitations of this study, a delay of up to 6 h before post-polymerization did not compromise FS, FM, cell viability, or pro-inflammatory gene expression. However, notable changes in DC and color suggest that the appearance and polymerization characteristics may be adversely affected, while mechanical and biological properties remained stable. |
