Keyword search (4,163 papers available)

"Tobacco" Keyword-tagged Publications:

Title Authors PubMed ID
1 Considering Drug-Associated Contexts in Substance Use Disorders and Treatment Development. LeCocq MR, Randall PA, Besheer J, Chaudhri N 31898285
CSBN
2 Vaping among youth and young adults: a "red alert" state. Al-Hamdani M, Hopkins DB, Park T 31664162
PSYCHOLOGY
3 Adolescent media use and its association to wellbeing in a Canadian national sample. Fitzpatrick C, Burkhalter R, Asbridge M 31024788
PERFORM
4 Predictors of Cigarette Smoking Initiation in Early, Middle, and Late Adolescence. O'Loughlin J, O'Loughlin EK, Wellman RJ, Sylvestre MP, Dugas EN, Chagnon M, Dutczak H, Laguë J, McGrath JJ 28318910
PERFORM

 

Title:Considering Drug-Associated Contexts in Substance Use Disorders and Treatment Development.
Authors:LeCocq MR,  Randall PA,  Besheer J,  Chaudhri N
Link:https://www.ncbi.nlm.nih.gov/pubmed/31898285?dopt=Abstract
DOI:10.1007/s13311-019-00824-2
Publication:Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Keywords:Alcohol;  Cue;  Relapse;  Tobacco;  Treatment; 
PMID:31898285 Category:Neurotherapeutics Date Added:2020-01-04
Dept Affiliation: CSBN
1 Department of Psychology, Center for Studies in Behavioural Neurobiology, Concordia University, 7141 Sherbrooke Street West, Room SP 244, Montreal, Quebec, H4B-1R6, Canada.
2 Department of Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Hershey, Pennsylvania, USA.
3 Department of Psychiatry, Bowles Center for Alcohol Studies, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
4 Department of Psychology, Center for Studies in Behavioural Neurobiology, Concordia University, 7141 Sherbrooke Street West, Room SP 244, Montreal, Quebec, H4B-1R6, Canada. nadia.chaudhri@concordia.ca.

Description:

Considering Drug-Associated Contexts in Substance Use Disorders and Treatment Development.

Neurotherapeutics. 2020 Jan 02;:

Authors: LeCocq MR, Randall PA, Besheer J, Chaudhri N

Abstract

Environmental contexts that are reliably associated with the use of pharmacologically active substances are hypothesized to contribute to substance use disorders. In this review, we provide an updated summary of parallel preclinical and human studies that support this hypothesis. Research conducted in rats shows that environmental contexts that are reliably paired with drug use can renew extinguished drug-seeking behavior and amplify responding elicited by discrete, drug-predictive cues. Akin to drug-associated contexts, interoceptive drug stimuli produced by the psychopharmacological effects of drugs can also influence learning and memory processes that play a role in substance use disorders. Findings from human laboratory studies show that drug-associated contexts, including social stimuli, can have profound effects on cue reactivity, drug use, and drug-related cognitive expectancies. This translationally relevant research supports the idea that treatments for substance use disorders could be improved by considering drug-associated contexts as a factor in treatment interventions. We conclude this review with ideas for how to integrate drug-associated contexts into treatment-oriented research based on 4 approaches: pharmacology, brain stimulation, mindfulness-based relapse prevention, and cognitive behavioral group therapy. Throughout, we focus on alcohol- and tobacco-related research, which are two of the most prevalent and commonly misused drugs worldwide for which there are known treatments.

PMID: 31898285 [PubMed - as supplied by publisher]




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