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PubMed Publications| Keyword search (4,163 papers available) |  |
"Systems biology" Keyword-tagged Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Exploiting fluctuations in gene expression to detect causal interactions between genes | Joly-Smith E; Talpur MM; Allard P; Papazotos F; Potvin-Trottier L; Hilfinger A; | 41401079 BIOLOGY |
| 2 | Protocol for evaluating neuronal activity and neurotransmitter release following amyloid-beta oligomer injections into the rat hippocampus | Hervé V; Bonenfant L; Amyot M; Balafrej R; Ali OBK; Benali H; Brouillette J; | 40131934 ENCS |
| 3 | Candida albicans exhibits heterogeneous and adaptive cytoprotective responses to anti-fungal compounds | Dumeaux V; Massahi S; Bettauer V; Mottola A; Dukovny A; Khurdia SS; Costa ACBP; Omran RP; Simpson S; Xie JL; Whiteway M; Berman J; Hallett MT; | 37888959 BIOLOGY |
| 4 | Sex differences in developmental patterns of neocortical astroglia: A mouse translatome database | Rurak GM; Simard S; Freitas-Andrade M; Lacoste B; Charih F; Van Geel A; Stead J; Woodside B; Green JR; Coppola G; Salmaso N; | 35108542 ENCS |
| 5 | Discovery of new vascular disrupting agents based on evolutionarily conserved drug action, pesticide resistance mutations, and humanized yeast | Garge RK; Cha HJ; Lee C; Gollihar JD; Kachroo AH; Wallingford JB; Marcotte EM; | 34849907 BIOLOGY |
| Title: | Protocol for evaluating neuronal activity and neurotransmitter release following amyloid-beta oligomer injections into the rat hippocampus | ||||
| Authors: | Hervé V, Bonenfant L, Amyot M, Balafrej R, Ali OBK, Benali H, Brouillette J | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/40131934/ | ||||
| DOI: | 10.1016/j.xpro.2025.103712 | ||||
| Publication: | STAR protocols | ||||
| Keywords: | Mass spectrometry; Neuroscience; Systems biology; | ||||
| PMID: | 40131934 | Category: | Date Added: | 2025-03-25 | |
| Dept Affiliation: |
ENCS
1 Department of Pharmacology and Physiology, Université de Montréal, Montréal, QC, Canada. Electronic address: vincent.herve@umontreal.ca. 2 Department of Pharmacology and Physiology, Université de Montréal, Montréal, QC, Canada. 3 Department of Electrical and Computer Engineering, Concordia University, Montréal, QC, Canada. 4 Department of Pharmacology and Physiology, Université de Montréal, Montréal, QC, Canada. Electronic address: jonathan.brouillette@umontreal.ca. |
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Description: |
In Alzheimer's disease, there is an imbalance in neurotransmitter release and altered neuronal activation. Here, we present a protocol approach to analyze neuronal activity by combining local field potential (LFP) recording with microdialysis within the same animal. We describe steps for measuring glutamate and GABA levels following hippocampal amyloid-beta oligomer (Aßo) injections in rats. We then detail procedures for assembling the electrode and cannula, surgical implantation and simultaneous in vivo LFP recording, interstitial fluid collection, and Aßo injections. |
