Keyword search (4,164 papers available)

"Sexual behavior" Keyword-tagged Publications:

Title Authors PubMed ID
1 Disruptive effects of d-amphetamine on conditioned sexual inhibition in the male rat Germé K; Persad D; Petit-Robinson J; Amir S; Pfaus JG; 40232387
PSYCHOLOGY
2 Non-Reproductive Sexual Behavior in Wild White-Thighed Colobus Monkeys (Colobus vellerosus) Teichroeb JA; Fox SA; Samartino S; Wikberg EC; Sicotte P; 36849676
BIOLOGY
3 Reciprocal effects of single or repeated exposure to methylphenidate or sex in adult male rats Pallikaras V; Mac Cionnaith CE; Rosales VCF; Arvanitogiannis A; Pfaus JG; 36544054
PSYCHOLOGY
4 Fos expression is increased in oxytocin neurons of female rats with a sexually conditioned mate preference for an individual male rat. Mac Cionnaith CE, Lemay A, Gomez-Perales EL, Robert G, Cernik R, Brake W, Pfaus JG 31647923
PSYCHOLOGY
5 Explaining mental health disparities for non-monosexual women: abuse history and risky sex, or the burdens of non-disclosure? Persson TJ; Pfaus JG; Ryder AG; 25223831
PSYCHOLOGY

 

Title:Reciprocal effects of single or repeated exposure to methylphenidate or sex in adult male rats
Authors:Pallikaras VMac Cionnaith CERosales VCFArvanitogiannis APfaus JG
Link:https://pubmed.ncbi.nlm.nih.gov/36544054/
DOI:10.1007/s00213-022-06300-8
Publication:Psychopharmacology
Keywords:CopulationCross-sensitizationLocomotionMethylphenidateRewardSensitizationSexual behaviorStimulant
PMID:36544054 Category: Date Added:2022-12-22
Dept Affiliation: PSYCHOLOGY
1 Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montréal, QC, Canada. vasilios.pallikaras@concordia.ca.
2 Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montréal, QC, Canada.
3 Department of Psychology and Life Sciences, Faculty of Humanities, Charles University, Prague, Czech Republic.
4 Division of Sexual Neuroscience, Center for Sexual Health and Intervention, Czech National Institute of Mental Health, Klecany, Czech Republic.

Description:

Rationale: Exposure to rewards can alter behavioral reactivity to them. For example, stimulants sensitize locomotor activation, whereas sexual experience sensitizes copulatory behaviors. Moreover, rewards can cross-sensitize one another. Although stimulants are known to cross-sensitize locomotor effects, the evidence for cross-sensitization between stimulants and sex is less clear.

Objectives: This study determined the effects of single and repeated pre-exposure to methylphenidate (MPH) or sex on one another in adult male rats.

Methods: Cross-sensitization between MPH (5 mg/kg) and sex (30 min with sexually experienced female) was examined. Adult male rats were pre-exposed to 0, 1, or 10 trials of either sex or MPH before being exposed to the other reward. Locomotor chambers were used in MPH trials. Bilevel chambers were used in sexual trials, and sexual behaviors were video scored.

Results: The amount of prior sexual experience differentially influenced the ceiling of MPH-dependent sensitization; in the last drug trial, locomotion was highest in males given 1 previous sexual trial compared with 0 or 10. Compared with MPH-naive males, pre-exposure to MPH (1 and 10 trials) reduced the number of ejaculations without impacting sexual performance (intromission/mount latency and frequency).

Conclusions: These findings indicate that the degree of pre-exposure to a reward can differentially affect reactivity to novel rewards. The results showed that previous findings of cross-sensitization between amphetamine and sex do not extend to MPH. However, exposure to MPH prior to sexual experience can increase the amount of sexual stimulation needed to achieve ejaculation.





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