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PubMed Publications| Keyword search (4,163 papers available) |  |
"Self-administration" Keyword-tagged Publications:
| Title: | Modulation of cue value and the augmentation of heroin seeking in chronically food-restricted male rats under withdrawal | ||||
| Authors: | Firas Sedki | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/37714221/ | ||||
| DOI: | 10.1016/j.pbb.2023.173636 | ||||
| Publication: | Pharmacology, biochemistry, and behavior | ||||
| Keywords: | Drug-associated cues; Food restriction; Heroin; Incentive value; Reward; Self-administration; | ||||
| PMID: | 37714221 | Category: | Date Added: | 2023-09-16 | |
| Dept Affiliation: | CSBN | ||||
Description: |
Food restriction augments drug seeking in abstinent rats. The underlying motivational mechanisms, however, remain unclear. We hypothesized that caloric restriction enhances the incentive value attributed to drug-associated cues and, in turn, augments drug seeking. Male rats were trained to lever-press for heroin, and then moved to the animal colony for a forced-abstinence period. Rats were maintained on free access to food (Sated) or subjected to 14 days of food restriction (FDR). In a series of... |
